This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eighteen chemicals including methylmercury hydroxide; methylmercuric chloride; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: F-box domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; FTH domain; and F-box A protein FB224.