WormBase Tree Display for Gene: WBGene00017500

WBGene00017500 SMap: S_parent: Sequence: F15E11
  Identity: Version: 2
    Name: CGC_name: pud-2.2 Person_evidence: WBPerson143
      Sequence_name: F15E11.14
      Molecular_name: F15E11.14
        F15E11.14.1
        CE16999
      Other_name: F15E11.f Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        CELE_F15E11.14 Accession_evidence: NDB BX284605
      Public_name: pud-2.2
    DB_info: Database: AceView gene 5C801
        WormQTL gene WBGene00017500
        WormFlux gene WBGene00017500
        NDB locus_tag CELE_F15E11.14
        NCBI gene 178710
        RefSeq protein NM_071237.1
        TREEFAM TREEFAM_ID TF319694
        TrEMBL UniProtAcc G5EBF3
        UniProt_GCRP UniProtAcc G5EBF3
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:58 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 20 Dec 2012 13:04:39 WBPerson2970 Name_change: CGC_name: pud-2.2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pud
    Allele (19)
    RNASeq_FPKM (74)
    Ortholog (16)
    Paralog: WBGene00017490 Caenorhabditis elegans From_analysis: TreeFam
            WormBase-Compara
      WBGene00017498 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00017499 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00017501 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00044489 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00044490 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00021236 Caenorhabditis elegans From_analysis: TreeFam
    Structured_description: Concise_description: pud-2.2, along with pud-2.1, encodes a 17.4 kDa protein (CE16999) with unknown function that is seven-fold more abundant in glp-1 mutant hermaphrodites (which lack a germline) than in normal hermaphrodites; in addition, the protein products of PUD-2.2/PUD-2.1 are more abundant in daf-2 mutant vs. wild-type adults during a temperature shift from 15 to 25 degrees C; pud-2.2(RNAi) animals have no obvious mutant phenotype (i.e., they have no obvious defect in fertility or germline maintenance); the PUD-2.2/PUD-2.1 proteins belong to a nematode-specific family including the paralogs PUD-1.1, PUD-1.2, PUD-3, and PUD-4. Paper_evidence: WBPaper00006020
            WBPaper00030894
          Curator_confirmed: WBPerson1843
          Date_last_updated: 12 Jun 2015 00:00:00
      Automated_description: Expressed in hypodermis. Is predicted to encode a protein with the following domains: Up-Regulated in long-lived daf-2 and Up-regulated in Daf-2. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F15E11.14
    Corresponding_transcript: F15E11.14.1
    Associated_feature: WBsf999496
      WBsf1019289
      WBsf231502
  Experimental_info: RNAi_result: WBRNAi00070096 Inferred_automatically: RNAi_primary
      WBRNAi00044734 Inferred_automatically: RNAi_primary
      WBRNAi00044722 Inferred_automatically: RNAi_primary
      WBRNAi00013371 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr11081
      Expr1148700
      Expr2015180
    Drives_construct: WBCnstr00017878
      WBCnstr00017881
      WBCnstr00018112
      WBCnstr00027252
    Construct_product: WBCnstr00017876
      WBCnstr00017878
      WBCnstr00017881
      WBCnstr00018112
      WBCnstr00027252
    Antibody: WBAntibody00001279
    Microarray_results (19)
    Expression_cluster: WBPaper00024704:Soluble_protein
      WBPaper00026640:Development_Group_O
      WBPaper00026640:embryo-to-L1_upregulated
      WBPaper00030894:daf-2(e1370ts)_upregulated
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00038104:DATS_upregulated
      WBPaper00038118:aak-2(gt33)_downregulated
      WBPaper00038168:lin-35_downregulated
      WBPaper00038438:P.lumniescens_24hr_downregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040209:B.thuringiensis_downregulated_MY15
      WBPaper00040209:B.thuringiensis_downregulated_MY18
      WBPaper00040209:B.thuringiensis_downregulated_N2
      WBPaper00040990:PA14_downregulated
      WBPaper00041954:ethanol_upregulated
      WBPaper00042215:wdr-23(tm1817)_downregulated
      WBPaper00042477:prp-8(RNAi)_downregulated_RNAseq
      WBPaper00044246:pgrn-1_ced-3_downregulated
      WBPaper00044760:somatic_specific
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00044857:BAR-1_upregulated
      WBPaper00045017:blmp-1(tm548)_downregulated
      WBPaper00045050:csr-1(hypomorph)_downregulated
      WBPaper00045257:bar-1(ga80)_downregulated
      WBPaper00045303:ZK1236.1(tm4178)_upregulated
      WBPaper00045401:N.parisii_30h_downregulated
      WBPaper00045401:N.parisii_40h_downregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045486:starvation_downregulated
      WBPaper00045521:Spermatogenic
      WBPaper00046217:clk-1(qm30)_upregulated
      WBPaper00046337:monosomal_N2_vs_daf-2_upregulated
      WBPaper00046496:Rifampicin_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00048971:daf-16(mgDf50)_downregulated_L1
      WBPaper00048980:aging_downregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049083:post-dauer-development_upregulated
      WBPaper00049098:heat-induced_hrde-1(tm1200)
      WBPaper00049217:TCER-1_upregulated
      WBPaper00049334:CE_intestine_enriched
      WBPaper00049368:daf-2(e1370)_downregulated
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049905:Age_variant_expression
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050412:cco-1(RNAi)_downregulated_N2
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:mir-34(OverExpression)_vs_N2_regulated_adult_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:ash-2(RNAi)_regulated_intestine
      WBPaper00051039:intestine_enriched
      WBPaper00053020:sid-3(ok973)_downregulated
      WBPaper00053258:Cry6Aa2-toxin_downregulated
      WBPaper00053295:lin-22(ot267)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053664:ins-11(tm1053)_upregulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053792:Ochrobactrum_upregulated
      WBPaper00053888:drh-3(rrr2)_upregulated
      WBPaper00054189:aging_regulated_protein
      WBPaper00054493:hpl-2(tm1489)_upregulated
      WBPaper00054872:egl-9(sa307)_downregulated
      WBPaper00054996:activated_sperm_CE
      WBPaper00054996:membranous_oraganelle_CE
      WBPaper00054996:unactivated_spermatid_CE
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055386:daf-2(e1370)_downregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00055827:daf-2(e1370)_downregulated
      WBPaper00055827:pfd-6(gk493446)_upregulated
      WBPaper00055941:hif-1(ia4)_upregulated
      WBPaper00055944:C.butyricum_vs_OP50_downregulated
      WBPaper00055971:nhl-2(ok818)_20C_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056034:pals-25(jy9)_downregulated
      WBPaper00056139:gut-microbiota_upregulated
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056443:DietaryRestriction_upregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059328:mrps-5(RNAi)_upregulated_protein
      WBPaper00059373:stt-3(RNAi)_downregulated
      WBPaper00059604:fluvastatin_upregulated_dlk-1(km12)
      WBPaper00059604:fluvastatin_upregulated_N2
      WBPaper00059605:simr-1(cmp36)_upregulated
      WBPaper00059739:hira-1(gk835598)_downregulated_adult
      WBPaper00059739:hira-1(gk835598)_downregulated_L1
      WBPaper00059739:hira-1(gk835598)_downregulated_L4
      WBPaper00059895:wounding_downregulated
      WBPaper00059987:Wounding_downregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060224:atf-6(ok551)_downregulated
      WBPaper00060273:isp-1(qm150)_downregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060634:fhod-1(tm2363)_upregulated
      WBPaper00060871:M.humicola-infection_24h_regulated
      WBPaper00060908:TEBP-2_interacting
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:M.braciatum_upregulated
      WBPaper00061040:eat-2(ad1116)_upregulated
      WBPaper00061340:M4_parent
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061530:nhr-49(e2144)_upregulated
      WBPaper00061613:human-amyloid-beta_downregulated
      WBPaper00061653:alh-4(hj221)_downregulated
      WBPaper00061853:tunicamycin_upregulated_N2
      WBPaper00062002:Day4-adult_secretome
      WBPaper00062056:lin-15B(we23)_downregulated
      WBPaper00062056:lin-35(n745)_downregulated
      WBPaper00062056:lin-37(n758)_downregulated
      WBPaper00062078:NMR-HspB1_regulated
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062293:clk-1(qm30)_downregulated
      WBPaper00062293:isp-1(qm150)_downregulated
      WBPaper00062345:bortezomib_4h_downregulated_N2
      WBPaper00062345:bortezomib_4h_downregulated_zip-1(jy13)
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00062497:xpf-1(tm2842)_upregulated
      WBPaper00062585:hlh-26(ok1453)_downregulated_E.faecium
      WBPaper00062590:Aging_downregulated_body-wall-muscle
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
      WBPaper00064071:NHR-49_interacting
      WBPaper00064130:Beta-Amyloid_8h_downregulated_mRNA
      WBPaper00064130:Beta-Amyloid_24h_downregulated_mRNA
      WBPaper00064502:spe-44(fx110)_downregulated
      WBPaper00064532:pals-22(jy3)_downregulated
      WBPaper00064532:pals-25(icb98)_downregulated
      WBPaper00064721:fasn-1(g14)_upregulated_starved
      WBPaper00064750:0.1mg-nanoplastics_upregulated_protein
      WBPaper00064750:1mg-nanoplastics_upregulated_protein
      WBPaper00064750:10mg-nanoplastics_upregulated_protein
      WBPaper00064769:him-17(me24)_downregulated
      WBPaper00064871:hypoxia_upregulated_F2
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00064952:Day10_vs_Day1_downregulated_25C
      WBPaper00064952:Day10_vs_Day5_downregulated_25C
      WBPaper00064952:Day10_vs_L4_downregulated_25C
      WBPaper00065005:sams-3(RNAi)_upregulated
      WBPaper00065005:sams-5(RNAi)_downregulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065086:JU1400_N.ironsii_regulated
      WBPaper00065315:mating_upregulated_Day2-7
      WBPaper00065315:mating_upregulated_Day6-7
      WBPaper00065392:Lb.delbrueckii_downregulated
      WBPaper00065392:Lb.gasseri_downregulated
      WBPaper00065392:Lb.plantarum_downregulated
      WBPaper00065392:Lb.reuteri_downregulated
      WBPaper00065392:Lb.rhamnosus_downregulated
      WBPaper00065392:P.pentosaceus_downregulated
      WBPaper00065578:gcn-1(nc40)_downregulated
      WBPaper00065581:hpk-1(pk1393)_downregulated
      WBPaper00065734:unc-25(e156)_downregulated
      WBPaper00065749:Heat-Shock_upregulated_N2
      WBPaper00065835:Day5_vs_Day1_upregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_downregulated_Day5
      WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00066038:mip-1(how5)_upregulated
      WBPaper00066110:Cisplatin_downregulated_diploid
      WBPaper00066110:Doxorubicin_downregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066232:ash-2(RNAi)_upregulated_WT
      WBPaper00066232:hsf-1(RNAi)_downregulated_WT
      cgc4489_group_3
      WBPaper00005124:progesterone_10-7M_regulated
      WBPaper00025141:unc-4::GFP_Enriched_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026980:intestine_enriched
      WBPaper00028789:PA14_vs_gacA_downregulated_8hr
      WBPaper00030839:Embryo_A_Class
      WBPaper00030985:Enterococcus_faecalis_downregulated
      WBPaper00030985:Photorhabdus_luminescens_downregulated
      WBPaper00031003:hlh_1_enriched
      WBPaper00031850:mdt-15(RNAi)_downregulated
      WBPaper00032062:age_regulated_genes
      WBPaper00035479:daf-16(RNAi)_downregulated
      WBPaper00035504:daf-2(e1370)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00035873:osmotically_regulated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_I
      WBPaper00037113:CPF_16C_down-regulated
      WBPaper00037113:CPF_DZN_16C_down-regulated
      WBPaper00037113:DZN_16C_down-regulated
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00038172:crh-1null_down_regulated
      WBPaper00038172:tax-6null_down_regulated
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00038231:Cry5B_2-fold_downregulated
      WBPaper00038427:lin-54_embryo_changed
      WBPaper00038462:aging_downregulated
      WBPaper00039866:ClassComp_daf-19_downregulated
      WBPaper00039866:SAM_daf-19_downregulated
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040426:CYD-1_CDK-4_downregulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.5
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040963:Q100_down
      WBPaper00040963:Q200_down
      WBPaper00040998:nhr-80_regulated
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HF_11d_0.2mM_Up
      WBPaper00041002:HF_11d_2.0mM_Up
      WBPaper00041211:RPW-24_Down
      WBPaper00041267:SpaceFlight_Downregulated
      WBPaper00041609:hpl-1_hpl-2_downregulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042128:gei-8(ok1671)_downregulated
      WBPaper00044091:Bpseudomallei_repressed_4h
      WBPaper00044091:Bpseudomallei_repressed_8h
      WBPaper00044091:Bpseudomallei_repressed_12h
      WBPaper00045015:acs-3(ft5)_downregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00045865:biofilm_upregulated_A
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_upregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00048624:hlh-25(ok1710)_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00049311:Ag-MNP_regulated
      WBPaper00049311:AgNO3_regulated
      WBPaper00050515:nipi-3(fr4)_downregulated
      WBPaper00050515:pmk-1(km25)_downregulated
      WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo
      WBPaper00053550:daf-19(m86)_upregulated_L1
      WBPaper00055435:AuNPs_upregulated
      WBPaper00055435:MUA-AuNP-0.5_upregulated
      WBPaper00056330:mrps-5(RNAi)_downregulated
      [cgc5976]:class_2
      [cgc6390]:mixed_spermatogenesis-somatic
    Interaction: WBInteraction000520383
      WBInteraction000554693
      WBInteraction000554695
      WBInteraction000556766
      WBInteraction000556768
      WBInteraction000581022
      WBInteraction000583424
  Map_info: Map: V Position: -14.8758
    Positive: Positive_clone: F15E11 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00024325
    WBPaper00027024
    WBPaper00030894
    WBPaper00037428
    WBPaper00046929
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene