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WormBase Tree Display for Gene: WBGene00002021

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Name Class

WBGene00002021SMapS_parentSequenceF52E1
IdentityVersion1
NameCGC_namehsp-17Person_evidenceWBPerson36
Sequence_nameF52E1.7
Molecular_nameF52E1.7a
F52E1.7a.1
CE04635
F52E1.7b
CE35323
F52E1.7b.1
Other_nameCELE_F52E1.7Accession_evidenceNDBBX284605
Public_namehsp-17
DB_infoDatabaseAceViewgene5I862
WormQTLgeneWBGene00002021
WormFluxgeneWBGene00002021
NDBlocus_tagCELE_F52E1.7
PanthergeneCAEEL|WormBase=WBGene00002021|UniProtKB=Q20660
familyPTHR45640
NCBIgene186113
RefSeqproteinNM_001028786.8
NM_001028787.7
TrEMBLUniProtAccQ7JP52
Q20660
UniProt_GCRPUniProtAccQ20660
OMIMgene123580
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:26WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classhsp
Allele (19)
StrainWBStrain00034982
WBStrain00034983
RNASeq_FPKM (74)
GO_annotation00068721
00068722
00068723
00068724
00068725
Ortholog (51)
ParalogWBGene00002011Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00002012Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00002013Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00002015Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00002016Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00002017Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
WBGene00002018Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00002019Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00002020Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
WBGene00002023Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00011906Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004798Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00008591Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00008592Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00002024Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00021943Caenorhabditis elegansFrom_analysisTreeFam
Panther
WBGene00014233Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
Structured_descriptionConcise_descriptionhsp-17 encodes a heat shock protein that is a member of the hsp16/hsp20/alpha-crystallin family of heat shock proteins; by homology, HSP-17 is predicted to function as a molecular chaperone that protects cells from heat-induced protein aggregation and denaturation.Curator_confirmedWBPerson1843
Date_last_updated25 Mar 2014 00:00:00
Automated_descriptionPredicted to enable unfolded protein binding activity. Predicted to be involved in protein refolding and response to heat. Predicted to be located in cytoplasm and nucleus. Expressed in excretory cell. Human ortholog(s) of this gene implicated in cataract 9 multiple types. Is an ortholog of human CRYAA (crystallin alpha A).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110266Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2388)
Molecular_infoCorresponding_CDSF52E1.7a
F52E1.7b
Corresponding_transcriptF52E1.7a.1
F52E1.7b.1
Other_sequence (51)
Associated_featureWBsf234078
Experimental_infoRNAi_resultWBRNAi00032621Inferred_automaticallyRNAi_primary
WBRNAi00113308Inferred_automaticallyRNAi_primary
WBRNAi00106386Inferred_automaticallyRNAi_primary
WBRNAi00047988Inferred_automaticallyRNAi_primary
WBRNAi00113079Inferred_automaticallyRNAi_primary
Expr_patternExpr15509
Expr1021825
Expr1151803
Expr1200266
Expr1200267
Expr2012622
Expr2030858
Drives_constructWBCnstr00036515
WBCnstr00042200
Construct_productWBCnstr00036515
WBCnstr00042200
AntibodyWBAntibody00002863
WBAntibody00002889
Microarray_results (22)
Expression_clusterWBPaper00032425:up_in_zfp-1
WBPaper00032528:L3_enriched
WBPaper00035269:cde-1_regulated
WBPaper00037047:aging_accelerated_insoluble_protein
WBPaper00037047:insoluble_protein
WBPaper00037682:sma-2_downregulated
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00037950:PVD-OLL-neurons_larva_enriched
WBPaper00037950:PVD-OLL-neurons_larva_SelectivelyEnriched
WBPaper00038168:lin-15B(n744)_upregulated
WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
WBPaper00040420:FLP_enriched
WBPaper00041075:hcf-1(-)_skn-1(+)_upregulated
WBPaper00042036:gpIs1(longevity)_regulated
WBPaper00042215:wdr-23(tm1817)_upregulated
WBPaper00042561:smgl-1(RNAi)_upregulated
WBPaper00044316:CH3HgCl_7.5uM_upregulated
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044638:daf-2(e1370)rsks-1(ok1255)_regulated
WBPaper00044656:tatn-1(qd182)_upregulated
WBPaper00044736:oscillating_dev_expression
WBPaper00044743:wdr-23_neuron_upregulated
WBPaper00045390:tunicamycin_upregulated
WBPaper00045390:ubc-9(RNAi)_upregulated
WBPaper00045401:N.parisii_30h_upregulated
WBPaper00045521:Gender_Neutral
WBPaper00045774:clk-1_downregulated
WBPaper00045934:wrn-1(gk99)_upregulated
WBPaper00046303:P.aeruginosa_downregulated_protein
WBPaper00046509:htz-1(ok3099)_downregulated
WBPaper00047132:glp-1(ts)-25C_upregulated
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_expressed
WBPaper00049217:DAF-16_downregulated
WBPaper00049290:rsks-1(sv31)_upregulated
WBPaper00049368:daf-2(e1370)_downregulated
WBPaper00049495:starvation-refeeding_regulated
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
WBPaper00049635:dop-1(vs100)_upregulated
WBPaper00049942:hsf-1(RNAi)_upregulated
WBPaper00050096:P.aeruginosa_upregulated
WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_100-cell-embryo
WBPaper00050163:chd-3(eh4)_downregulated_100-cell-embryo
WBPaper00050344:ASER-neuron_enriched
WBPaper00050448:KGB-1-induced
WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050636:aging_regulated_insoluble_protein
WBPaper00050726:starvation_regulated_LowSalt
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00051039:intestine_enriched
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00051245:intestine_specific
WBPaper00051305:vit-2(ac3)_upregulated
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00053020:sid-3(ok973)_upregulated
WBPaper00053020:sta-1(ok587)_upregulated
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053388:dauer_regulated_Cluster5
WBPaper00053599:female_vs_male_downregulated
WBPaper00053599:oocyte_vs_mitosis_upregulated
WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00053814:25C_downregulated_PY79
WBPaper00053814:OP50_vs_PY79_downregulated_PY79
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Psora-Allantoin_downregulated
WBPaper00055354:Psora_downregulated
WBPaper00055354:Rapamycin-Metformin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055354:Rifampicin_downregulated
WBPaper00055386:eat-2(ad465)_upregulated
WBPaper00055482:pmt-2(RNAi)_upregulated
WBPaper00055482:Tunicamycin_downregulated
WBPaper00055626:pry-1(mu38)_downregulated
WBPaper00055827:daf-2(e1370)_upregulated
WBPaper00055941:atfs-1(et15)_upregulated
WBPaper00055941:atfs-1(gk3094)_upregulated
WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
WBPaper00056034:pals-22(jy3)_upregulated
WBPaper00056034:pals-25(jy9)_upregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056139:soil-microbiota_downregulated
WBPaper00056167:Cry5B_downregulated
WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
WBPaper00056284:ints-11(RNAi)_upregulated
WBPaper00056290:hsp-6(mg585)_upregulated
WBPaper00056293:rpl-5(0)-rpl-33(0)_upregulated
WBPaper00056443:DietaryRestriction_downregulated
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1
WBPaper00056586:kri-1(ok1251)_upregulated
WBPaper00056586:KRI-1_interacting
WBPaper00056731:human-amylin_downregulated
WBPaper00056826:hmc_biased
WBPaper00056868:P.aeruginosa_upregulated_smallRNA
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00056997:NMAD-1_interacting
WBPaper00057006:DietaryRestriction_downregulated
WBPaper00057068:Cadmium_upregulated
WBPaper00057154:HeatShock_upregulated_mRNA
WBPaper00057254:MWCNT_downregulated_mRNA
WBPaper00058598:mex-1(or286)_upregulated
WBPaper00058598:mex-3(eu149)_upregulated
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058598:spn-4(tm291)_upregulated
WBPaper00058665:graphene-oxide_upregulated_mRNA
WBPaper00058711:paraquat_downregulated
WBPaper00058725:sftb-1(cer6)_upregulated
WBPaper00058725:sftb-1(cer39)_upregulated
WBPaper00058948:PA14_downregulated
WBPaper00059027:neuron-synapses_depleted
WBPaper00059253:sucrose_upregulated
WBPaper00059373:stt-3(RNAi)_upregulated
WBPaper00059426:Ag-nanoparticles_upregulated
WBPaper00059537:ngn-1(ok2200)_upregulated
WBPaper00059566:wdr-23(mac32)_upregulated
WBPaper00059598:HeatShock_upregulated
WBPaper00059604:fluvastatin_downregulated_dlk-1(km12)
WBPaper00059604:fluvastatin_downregulated_N2
WBPaper00059605:MUT-16_interacting
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059739:hira-1(gk835598)_upregulated_adult
WBPaper00059754:E.faecalis_OG1RF_upregulated
WBPaper00059839:S.maltophilia_regulated
WBPaper00059895:wounding_upregulated
WBPaper00059987:Wounding_upregulated
WBPaper00060014:set-2(tm1630)_upregulated
WBPaper00060084:cco-1(RNAi)_upregulated_lin-40(yth27)
WBPaper00060084:cco-1(RNAi)_upregulated_N2
WBPaper00060100:SiNP_upregulated_mRNA
WBPaper00060273:isp-1(qm150)_upregulated
WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060399:CoCl2_6hr_upregulated_N2
WBPaper00060445:nfki-1(cer1)_upregulated_L1
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
WBPaper00061007:HB101_upregulated
WBPaper00061007:S.aquatilis_upregulated
WBPaper00061007:X.citri_upregulated
WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061319:pnp-1(jy90)_upregulated
WBPaper00061340:Excretory_cell
WBPaper00061340:mc1
WBPaper00061340:mc2
WBPaper00061340:mc3
WBPaper00061340:Pharyngeal_marginal_cell
WBPaper00061341:28C_24h_upregulated
WBPaper00061341:28C_48h_upregulated
WBPaper00061377:MYRF-2_interacting
WBPaper00061405:S.aureus_upregulated_starvation
WBPaper00061409:neuronal-fzo-1(RNAi)_upregulated
WBPaper00061439:unc-30(ok613)_upregulated
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061479:HDA-1_interacting_protein
WBPaper00061527:F54D5.3_7003-F54D5.3_7004
WBPaper00061530:nhr-49(e2144)_upregulated
WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062184:PA14_upregulated
WBPaper00062237:dnj-21(RNAi)_upregulated_protein
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062345:bortezomib_4h_upregulated_N2
WBPaper00062345:bortezomib_4h_upregulated_zip-1(jy13)
WBPaper00062354:H.zoospora_6h_regulated
WBPaper00062498:PPM-1.D_interacting
WBPaper00062590:Aging_upregulated_neuron
WBPaper00062684:pathogen_upregulated_CB4856
WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
WBPaper00064005:starvation_downregulated_N2_mRNA
WBPaper00064005:starvation_upregulated_aptf-1(gk794)_protein
WBPaper00064071:NHR-49_interacting
WBPaper00064130:Beta-Amyloid_8h_upregulated_mRNA
WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
WBPaper00064156:lipl-4(overexpress)_upregulated
WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
WBPaper00064403:Heat-killed-E.Coli_upregulated
WBPaper00064502:spe-44(fx110)_downregulated
WBPaper00064539:nhr-114(gk849)_upregulated
WBPaper00064637:cox-5B(RNAi)_upregulated
WBPaper00064727:daf-2(e1370)_downregulated
WBPaper00064769:him-17(me24)_upregulated
WBPaper00064871:PA14_upregulated_AWA
WBPaper00065029:cadmium_upregulated
WBPaper00065086:JU1400_N.ironsii_regulated
WBPaper00065086:N2_N.ferruginous_regulated
WBPaper00065086:N2_N.ironsii_regulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065331:100nM-ivermectin_upregulated
WBPaper00065373:Cisplatin_upregulated_WT
WBPaper00065373:sek-1(km4)_downregulated_cisplatin
WBPaper00065373:sek-1(km4)_downregulated_Ref
WBPaper00065392:Lb.rhamnosus_upregulated
WBPaper00065734:unc-25(e156)_upregulated
WBPaper00065749:Heat-Shock-With-Recovery_upregulated_N2
WBPaper00065841:3_4
WBPaper00065841:9_0
WBPaper00065841:9_1
WBPaper00065841:9_2
WBPaper00065841:24_0
WBPaper00065841:24_1
WBPaper00065841:26_0
WBPaper00065841:26_1
WBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein
WBPaper00065975:P-body_vs_oocyte_depleted
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066110:tetraploid_vs_diploid_upregulated
WBPaper00066204:CdCl2_upregulated_mRNA
WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
WBPaper00066232:hsf-1(RNAi)_upregulated_WT
cgc4386_cluster_1_4
cgc4489_group_24
WBPaper00025141:N2_Expressed_Genes
WBPaper00026929:Resveratrol_regulated_daf-16
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00028789:PA14_vs_OP50_upregulated_8hr
WBPaper00030985:Photorhabdus_luminescens_upregulated
WBPaper00031003:0hr_muscle_depleted
WBPaper00031003:24hr_muscle_depleted
WBPaper00031003:total_muscle_depleted
WBPaper00031060:2-deoxy-D-glucose_upregulated
WBPaper00031850:mdt-15(RNAi)_upregulated
WBPaper00032948:FedUp
WBPaper00035227:heat_shock_regulated
WBPaper00035873:dpy-10_regulated
WBPaper00036286:Pattern_I
WBPaper00036383:ash-2_Day8_regulated
WBPaper00037695:LD_DD_6-day
WBPaper00040823:alg-1(gk214)_upregulated
WBPaper00040876:mir-35_downregulated
WBPaper00040963:Q100_down
WBPaper00040963:Q200_down
WBPaper00041002:HQ_3d_2.0mM_Up
WBPaper00041211:RPW-24_Up
WBPaper00041370:spg-7(RNAi)_upregulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041609:hpl-1_hpl-2_upregulated
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
WBPaper00042274:tbx-2(bx59)_upregulated
WBPaper00044091:Bpseudomallei_induced_8h
WBPaper00044091:Bpseudomallei_induced_12h
WBPaper00045374:Benzene_upregulated
WBPaper00045401:N.parisii_34h_upregulated_N2
WBPaper00045673:colistin_upregulated
WBPaper00047070:xpa-1_UV_upregulated
WBPaper00050407:hsp-6(RNAi)_upregulated
WBPaper00050515:nipi-3(fr4)_upregulated
WBPaper00053236:Starvation_regulated_N2
WBPaper00056330:mrps-5(RNAi)_upregulated
WBPaper00057098:SiO2-nanoparticles_downregulated
[cgc6390]:Cluster_C
Interaction (117)
Map_infoMapVPosition1.36669Error0.004297
PositivePositive_cloneF52E1Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4368
Pseudo_map_position
Reference (20)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene