WormBase Tree Display for Gene: WBGene00002020

WBGene00002020 SMap: S_parent: Sequence: T27E4
  Identity: Version: 1
    Name: CGC_name: hsp-16.49 Person_evidence: WBPerson36
      Sequence_name: T27E4.9
      Molecular_name: T27E4.9
        T27E4.9.1
        CE14251
      Other_name: hsp-16
        CELE_T27E4.9 Accession_evidence: NDB BX284605
      Public_name: hsp-16.49
    DB_info: Database: AceView gene 5J570
        WormFlux gene WBGene00002020
        NDB locus_tag CELE_T27E4.9
        NCBI gene 179288
        RefSeq protein NM_072955.3
        SwissProt UniProtAcc P02513
        UniProt_GCRP UniProtAcc P02513
        OMIM gene 123580
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:26 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: hsp
    Allele: WBVar01499903
      WBVar01500129
      WBVar01499419
      WBVar01499420
      WBVar01499056
      WBVar01499249
      WBVar00250229
      WBVar01499316
    In_cluster: HSP16A
    RNASeq_FPKM (74)
    GO_annotation: 00105708
      00105759
      00106140
    Ortholog (88)
    Paralog (17)
    Structured_description: Concise_description: hsp-16.49 encodes a 16-kD heat shock protein (HSP) that is a member of the hsp16/hsp20/alphaB-crystallin (HSP16) family of heat shock proteins, and that is identical to the protein encoded by hsp-16.48; HSP-16.49 is likely to function as a passive ligand temporarily preventing unfolded proteins from aggregating. Paper_evidence: WBPaper00004424
            WBPaper00013029
            WBPaper00013239
            WBPaper00013280
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable unfolded protein binding activity. Involved in endoplasmic reticulum unfolded protein response. Human ortholog(s) of this gene implicated in cataract 9 multiple types. Is an ortholog of human CRYAA (crystallin alpha A). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0110266 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2388)
  Molecular_info: Corresponding_CDS: T27E4.9
    Corresponding_transcript: T27E4.9.1
    Other_sequence (109)
    Associated_feature: WBsf234179
  Experimental_info: RNAi_result: WBRNAi00093732 Inferred_automatically: RNAi_primary
      WBRNAi00063167 Inferred_automatically: RNAi_primary
      WBRNAi00106385 Inferred_automatically: RNAi_primary
      WBRNAi00106384 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1157863
      Expr2012621
      Expr2030857
    Drives_construct: WBCnstr00010087
      WBCnstr00036516
    Construct_product: WBCnstr00036516
    Antibody: WBAntibody00001859
    Microarray_results: SMD_T27E4.9
      Aff_T27E4.3
    Expression_cluster (159)
    Interaction (28)
  Map_info: Map: V Position: 1.9262 Error: 0.001695
    Positive: Positive_clone: T27E4 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4419
    Pseudo_map_position
  Reference (61)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene