WormBase Tree Display for Gene: WBGene00002023
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| WBGene00002023 | SMap | S_parent | Sequence | C09B8 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | hsp-25 | Person_evidence | WBPerson36 | |||||
| Sequence_name | C09B8.6 | ||||||||
| Molecular_name | C09B8.6a | ||||||||
| C09B8.6a.1 | |||||||||
| CE02466 | |||||||||
| C09B8.6b | |||||||||
| CE33558 | |||||||||
| C09B8.6c | |||||||||
| CE37953 | |||||||||
| C09B8.6b.1 | |||||||||
| C09B8.6c.1 | |||||||||
| C09B8.6c.2 | |||||||||
| Other_name | HSP25 | Paper_evidence | WBPaper00036199 | ||||||
| CELE_C09B8.6 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | hsp-25 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:26 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hsp | ||||||||
| Allele (81) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00059380 | ||||||||
| 00059381 | |||||||||
| 00059382 | |||||||||
| 00059383 | |||||||||
| 00059384 | |||||||||
| 00059385 | |||||||||
| 00059386 | |||||||||
| Ortholog (35) | |||||||||
| Paralog (17) | |||||||||
| Structured_description | Concise_description | hsp-25 encodes a member of the small heat shock family of proteins; HSP-25 is expressed throughout development and in vitro, exhibits chaperone activity; HSP-25 localizes to: 1) dense bodies and M lines in body wall muscle, 2) the lining of the pharynx, and 3) to cell-cell junctions in the spermathecal wall; consistent with a role in myofibril organization, HSP-25 binds vinculin and alpha-actinin in vitro. | Paper_evidence | WBPaper00003970 | |||||
| WBPaper00013029 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 02 Mar 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable unfolded protein binding activity. Predicted to be involved in protein refolding and response to heat. Located in M band and striated muscle dense body. Expressed in body wall musculature; gonad; pharynx; and spermatheca. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2L and distal hereditary motor neuronopathy type 2A. Is an ortholog of human HSPB8 (heat shock protein family B (small) member 8). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111208 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:30171) | ||||
| DOID:0110174 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:30171) | ||||||
| Molecular_info | Corresponding_CDS | C09B8.6a | |||||||
| C09B8.6b | |||||||||
| C09B8.6c | |||||||||
| Corresponding_transcript | C09B8.6a.1 | ||||||||
| C09B8.6b.1 | |||||||||
| C09B8.6c.1 | |||||||||
| C09B8.6c.2 | |||||||||
| Other_sequence (120) | |||||||||
| Associated_feature (19) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00097033 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00106387 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076103 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00040161 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00033415 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00010508 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1087 | ||||||||
| Expr1088 | |||||||||
| Expr4163 | |||||||||
| Expr15507 | |||||||||
| Expr1018056 | |||||||||
| Expr1031178 | |||||||||
| Expr1144237 | |||||||||
| Expr2012624 | |||||||||
| Expr2030860 | |||||||||
| Drives_construct | WBCnstr00036514 | ||||||||
| WBCnstr00042198 | |||||||||
| Construct_product | WBCnstr00036514 | ||||||||
| WBCnstr00042198 | |||||||||
| Antibody | WBAntibody00000270 | ||||||||
| Microarray_results (33) | |||||||||
| Expression_cluster (201) | |||||||||
| Interaction (48) | |||||||||
| Map_info | Map | X | Position | -3.82033 | Error | 0.011016 | |||
| Positive | Positive_clone | C09B8 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4562 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00013029 | ||||||||
| WBPaper00036199 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00060685 | |||||||||
| WBPaper00061766 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
