This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
Enriched in several structures, including ABarpapaaa; ABplaaaaaa; ABplpaaaaa; ABplpaaapa; and amphid neurons based on single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and let-60 based on microarray; tiling array; and RNA-seq studies. Is affected by twelve chemicals including Mercuric Chloride; multi-walled carbon nanotube; and stavudine based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box domain; F-box associated; and F-box associated domain, type 2.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.