ptr-14 encodes a nematode-specific member of the sterol sensing domain(SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) andhuman PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-14is weakly required for normal molting from L4 to adult stages; PTR-14 isalso required for normal growth to full size and locomotion.
Predicted to enable transmembrane transporter activity. Involved in molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.