WormBase Tree Display for Gene: WBGene00004232

WBGene00004232 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: Y38F1A
  Identity: Version: 1
    Name: CGC_name: ptr-18 Person_evidence: WBPerson349
      Sequence_name: Y38F1A.3
      Molecular_name: Y38F1A.3
        Y38F1A.3.1
        CE43376
      Other_name: CELE_Y38F1A.3 Accession_evidence: NDB BX284602
      Public_name: ptr-18
    DB_info: Database: AceView gene 2N267
        WormQTL gene WBGene00004232
        WormFlux gene WBGene00004232
        NDB locus_tag CELE_Y38F1A.3
        Panther gene CAEEL|WormBase=WBGene00004232|UniProtKB=Q9XWL9
          family PTHR10796
        NCBI gene 174940
        RefSeq protein NM_064360.5
        SwissProt UniProtAcc Q9XWL9
        TREEFAM TREEFAM_ID TF331806
        UniProt_GCRP UniProtAcc Q9XWL9
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:34 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ptr
    Allele (280)
    Strain: WBStrain00033217
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog (42)
    Paralog (30)
    Structured_description: Concise_description: ptr-18 encodes a nematode-specific member of the sterol sensing domain(SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) andhuman PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-18is strongly required for normal molting from L3 to adult stage (a roleconserved in C. briggsae); PTR-18 is also required for male taildevelopment and vulval morphogenesis, and (partly) for endocytosis ofyolk by oocytes. Paper_evidence: WBPaper00026841
            WBPaper00027263
          Curator_confirmed: WBPerson567
          Date_last_updated: 08 Nov 2006 00:00:00
      Automated_description: Involved in endocytosis and molting cycle. Acts upstream of or within nematode male tail mating organ morphogenesis. Located in apical plasma membrane. Expressed in hypodermal cell; seam cell; and ventral cord blast cell. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y38F1A.3
    Corresponding_CDS_history: Y38F1A.3:wp114
    Corresponding_transcript: Y38F1A.3.1
    Other_sequence (15)
    Associated_feature (11)
  Experimental_info: RNAi_result: WBRNAi00020292 Inferred_automatically: RNAi_primary
      WBRNAi00056034 Inferred_automatically: RNAi_primary
      WBRNAi00076936 Inferred_automatically: RNAi_primary
      WBRNAi00076926 Inferred_automatically: RNAi_primary
      WBRNAi00076958 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr16249
      Expr1014505
      Expr1032083
      Expr1159557
      Expr2015161
      Expr2033399
    Drives_construct: WBCnstr00035619
      WBCnstr00042860
    Construct_product: WBCnstr00035619
    Microarray_results (21)
    Expression_cluster (257)
    Interaction (125)
  Map_info: Map: II Position: 12.9151 Error: 0.190407
    Positive: Positive_clone: Y38F1A Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00004265
    WBPaper00024393
    WBPaper00026841
    WBPaper00031097
    WBPaper00038491
    WBPaper00055090
    WBPaper00057376
    WBPaper00061320
    WBPaper00061938
    WBPaper00064105
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene