WormBase Tree Display for Expr_pattern: Expr16249
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| Expr16249 | Expression_of | Gene | WBGene00004232 | ||
|---|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00004232 | ||||
| Expression_data | Life_stage | WBls:0000020 | Anatomy_term | WBbt:0005753 | |
| WBbt:0007846 | |||||
| WBbt:0008115 | |||||
| Anatomy_term | WBbt:0005753 | Certain | |||
| Life_stage | WBls:0000020 | ||||
| WBbt:0007846 | Certain | ||||
| Life_stage | WBls:0000020 | ||||
| WBbt:0008115 | Certain | ||||
| Life_stage | WBls:0000020 | ||||
| GO_term | GO:0016324 | ||||
| Type | Reporter_gene | ||||
| Pattern | PTR-18 and GRL-7 are temporally localized along the periphery of the apical membranes of hypodermal and P neuronal progenitor cells during late embryogenesis and are subsequently targeted to lysosomal degradation before hatching. PTR-18::GFP was first detected along the apical side of surface cells that cover the whole body, which consists of hypodermal, seam, and P cells at the 3-fold stage during embryogenesis. During the early time point, the majority of the 3-fold embryos initially showed apical localization of PTR-18::GFP. As development continued, the percentage of the apical localization decreased, the fraction that exhibited localization of PTR-18::GFP in the vesicular punctate structures increased, and eventually, most of the embryos did not show its expression. These observations indicate that PTR-18::GFP first localizes at the apical side of the hypodermal, seam, and P cells, subsequently accumulates in the vesicular structures, and eventually disappears before hatching. PTR-18::GFP was alsoexpressed in the descendants of P cells, rectal epithelial F, K, and U cells, and some seam cells in late L1 larvae. | ||||
| Reference | WBPaper00061320 | ||||
| Transgene | WBTransgene00033556 |
