WormBase Tree Display for Gene: WBGene00004237
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| WBGene00004237 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | CHROMOSOME_I | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | ptr-23 | Person_evidence | WBPerson349 | |||||
| Sequence_name | ZK270.1 | ||||||||
| Molecular_name | ZK270.1 | ||||||||
| ZK270.1.1 | |||||||||
| CE15305 | |||||||||
| ZK270.1.2 | |||||||||
| Other_name | CELE_ZK270.1 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | ptr-23 | ||||||||
| DB_info | Database | AceView | gene | 1P503 | |||||
| WormQTL | gene | WBGene00004237 | |||||||
| WormFlux | gene | WBGene00004237 | |||||||
| NDB | locus_tag | CELE_ZK270.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004237|UniProtKB=G5EE13 | |||||||
| family | PTHR10796 | ||||||||
| NCBI | gene | 173362 | |||||||
| RefSeq | protein | NM_061202.7 | |||||||
| TREEFAM | TREEFAM_ID | TF331806 | |||||||
| TrEMBL | UniProtAcc | G5EE13 | |||||||
| UniProt_GCRP | UniProtAcc | G5EE13 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ptr | ||||||||
| Allele (98) | |||||||||
| Strain | WBStrain00037725 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00015243 | ||||||||
| 00015244 | |||||||||
| 00015245 | |||||||||
| 00015246 | |||||||||
| 00015247 | |||||||||
| 00015248 | |||||||||
| 00015249 | |||||||||
| 00015250 | |||||||||
| 00112529 | |||||||||
| Ortholog (33) | |||||||||
| Paralog (30) | |||||||||
| Structured_description | Concise_description | ptr-23 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-23 is strongly required for normal molting from L4 to adult stages (a role conserved in C. briggsae); PTR_23 also functions in a pathway with the mucin-like protein OSM-8 to regulate the osmotic stress response; PTR-23 activity is additionally required for normal male tail development, vulval morphogenesis, adult alae formation, and (partly) for endocytosis of yolk by oocytes; a PTR-23::GFP reporter fusion protein is expressed in the hypodermis where it localizes to discrete foci. | Paper_evidence | WBPaper00024393 | |||||
| WBPaper00026763 | |||||||||
| WBPaper00026841 | |||||||||
| WBPaper00027263 | |||||||||
| WBPaper00027756 | |||||||||
| WBPaper00038064 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 20 Apr 2011 00:00:00 | ||||||||
| Automated_description | Involved in endocytosis and molting cycle. Acts upstream of or within nematode male tail mating organ morphogenesis. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Expressed in hypodermis. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | ZK270.1 | |||||||
| Corresponding_transcript | ZK270.1.1 | ||||||||
| ZK270.1.2 | |||||||||
| Other_sequence (54) | |||||||||
| Associated_feature | WBsf716513 | ||||||||
| WBsf986260 | |||||||||
| WBsf986261 | |||||||||
| WBsf986262 | |||||||||
| WBsf986263 | |||||||||
| WBsf1011308 | |||||||||
| WBsf1011309 | |||||||||
| WBsf1011310 | |||||||||
| WBsf218842 | |||||||||
| WBsf218843 | |||||||||
| Experimental_info | RNAi_result (25) | ||||||||
| Expr_pattern | Expr11208 | ||||||||
| Expr1014683 | |||||||||
| Expr1032088 | |||||||||
| Expr1162752 | |||||||||
| Expr2015167 | |||||||||
| Expr2033405 | |||||||||
| Drives_construct | WBCnstr00018221 | ||||||||
| WBCnstr00035615 | |||||||||
| Construct_product | WBCnstr00018221 | ||||||||
| WBCnstr00035615 | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (234) | |||||||||
| Interaction (17) | |||||||||
| Map_info | Map | I | Position | 28.2667 | Error | 0.069277 | |||
| Positive | Positive_clone | ZK270 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (18) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
