WormBase Tree Display for Gene: WBGene00004217
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| WBGene00004217 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C32E8 | ||||||
| Identity | Version | 2 | |||||||
| Name | CGC_name | ptr-2 | Person_evidence | WBPerson349 | |||||
| Sequence_name | C32E8.8 | ||||||||
| Molecular_name | C32E8.8 | ||||||||
| C32E8.8.1 | |||||||||
| CE08532 | |||||||||
| Other_name | let-575 | Person_evidence | WBPerson533 | ||||||
| CELE_C32E8.8 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | ptr-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 05 Mar 2015 09:57:53 | WBPerson2970 | Event | Acquires_merge | WBGene00002754 | ||||
| Name_change | Other_name | let-575 | |||||||
| Acquires_merge | WBGene00002754 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ptr | ||||||||
| Allele (52) | |||||||||
| Legacy_information | [C.elegansII] h345 : lethal. OA1: h728. [KR] | ||||||||
| Strain | WBStrain00023809 | ||||||||
| WBStrain00036120 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Ortholog (39) | |||||||||
| Paralog (30) | |||||||||
| Structured_description | Concise_description | ptr-2 encodes an ortholog of Drosophila and human PTCHD3, which definesone of seven paralogous families of sterol sensing domain (SSD)proteins; PTR-2 is required for cytokinesis in somatic cells, but not inthe germline (the converse of PTC-1's function); PTR-2 is partiallyrequired for normal molting from L4 to adult stages; PTR-2 is alsorequired for normal male tail development, growth to full size,locomotion, and viability. | Paper_evidence | WBPaper00004265 | |||||
| WBPaper00026592 | |||||||||
| WBPaper00026763 | |||||||||
| WBPaper00026841 | |||||||||
| WBPaper00027263 | |||||||||
| WBPaper00027756 | |||||||||
| WBPaper00028381 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 08 Nov 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable transmembrane transporter activity. Involved in mitotic cytokinesis and molting cycle. Acts upstream of or within nematode male tail mating organ morphogenesis. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human PTCHD1 (patched domain containing 1) and PTCHD4 (patched domain containing 4). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:12849 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:26392) | ||||
| Molecular_info | Corresponding_CDS | C32E8.8 | |||||||
| Corresponding_transcript | C32E8.8.1 | ||||||||
| Other_sequence (57) | |||||||||
| Associated_feature | WBsf983244 | ||||||||
| WBsf983245 | |||||||||
| WBsf1009563 | |||||||||
| WBsf219177 | |||||||||
| WBsf219178 | |||||||||
| Experimental_info | RNAi_result (18) | ||||||||
| Expr_pattern | Expr1026280 | ||||||||
| Expr1032074 | |||||||||
| Expr1145715 | |||||||||
| Expr2015169 | |||||||||
| Expr2033407 | |||||||||
| Drives_construct | WBCnstr00035630 | ||||||||
| Construct_product | WBCnstr00035630 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (210) | |||||||||
| Interaction (68) | |||||||||
| Map_info | Map | I | Position | -2.57574 | Error | 0.017245 | |||
| Hide_under | WBGene00002740 | ||||||||
| Positive | Positive_clone | C32E8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Negative | Outside_rearr | hDf24 | |||||||
| Mapping_data | Multi_point | 5164 | |||||||
| 4637 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (19) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
