WormBase Tree Display for Gene: WBGene00017576

WBGene00017576 SMap: S_parent: Sequence: CHROMOSOME_IV
  Identity: Version: 2
    Name: CGC_name: cdh-8 Person_evidence: WBPerson698
      Sequence_name: F18F11.3
      Molecular_name (27)
      Other_name: CELE_F18F11.3 Accession_evidence: NDB BX284604
      Public_name: cdh-8
    DB_info: Database: AceView gene 4B111
        WormQTL gene WBGene00017576
        WormFlux gene WBGene00017576
        NDB locus_tag CELE_F18F11.3
        Panther gene CAEEL|WormBase=WBGene00017576|UniProtKB=U4PM66
          family PTHR24026
        NCBI gene 184652
        RefSeq protein NM_001307480.3
            NM_001307486.4
            NM_001307430.3
            NM_001307487.3
            NM_001307483.3
            NM_001307481.3
            NM_001307484.3
            NM_001307485.3
            NM_001307482.3
        TrEMBL UniProtAcc U4PBD1
            U4PEK5
            U4PBI3
            U4PEL1
            U4PBR0
            U4PM66
            U4PBR4
            U4PBD6
            U4PRG1
        UniProt_GCRP UniProtAcc U4PM66
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:59 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 19 Oct 2005 17:52:08 WBPerson1867 Event: Acquires_merge: WBGene00000400
      Acquires_merge: WBGene00000400
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cdh
    Allele: WBVar02158506
      WBVar00879755
      WBVar00879756
      WBVar00879757
      WBVar00879758
      WBVar00879759
      WBVar00879760
      WBVar00879761
      WBVar00879762
      WBVar00879763
      WBVar00879764
      WBVar00879765
      WBVar00879766
      WBVar01450078
      WBVar00879767
      WBVar01450079
      WBVar00879768
      WBVar01450080
      WBVar00879769
      WBVar01450081
      WBVar00879770
      WBVar01450082
      WBVar00879771
      WBVar00879772
      WBVar01450083
      WBVar01499166
      WBVar02133166
      WBVar00879773
      WBVar00879774
      WBVar00415063
      WBVar02133167
      WBVar00879775
      WBVar02133168
      WBVar00415064
      WBVar00879776
      WBVar02133169
      WBVar00415065
      WBVar00415066
      WBVar00879777
      WBVar02133170
      WBVar00415067
      WBVar00879778
      WBVar00879779
      WBVar00415068
      WBVar00415069
      WBVar00879780
      WBVar00415070
      WBVar00879781
      WBVar00415071
      WBVar00879782
      WBVar00879783
      WBVar00415072
      WBVar00879784
      WBVar00415073
      WBVar00879785
      WBVar00415074
      WBVar00879786
      WBVar00415075
      WBVar00415076
      WBVar01646893
      WBVar00879787
      WBVar01646894
      WBVar00415077
      WBVar00879788
      WBVar01646895
      WBVar00415078
      WBVar00879789
      WBVar00879790
      WBVar01646896
      WBVar00415079
      WBVar01646897
      WBVar00415080
      WBVar00879791
      WBVar00415081
      WBVar00879792
      WBVar00879793
      WBVar00415082
      WBVar00415083
      WBVar00879794
      WBVar00415084
      WBVar00879795
      WBVar00879796
      WBVar00415085
      WBVar00879797
      WBVar00415086
      WBVar00415087
      WBVar00879798
      WBVar02048957
      WBVar00415088
      WBVar00879799
      WBVar00415089
      WBVar00879800
      WBVar00415090
      WBVar00879801
      WBVar00879802
      WBVar00415091
      WBVar00879803
      WBVar00415092
      WBVar00879804
      WBVar00415093
      WBVar02148092
      WBVar00879805
      WBVar00415094
      WBVar00260620
      WBVar00879806
      WBVar00415095
      WBVar00415096
      WBVar00879807
      WBVar01499384
      WBVar00415097
      WBVar00879808
      WBVar01499385
      WBVar00415098
      WBVar00879809
      WBVar00879810
      WBVar00415099
      WBVar00415100
      WBVar00879811
      WBVar01607464
      WBVar00415101
      WBVar00879812
      WBVar00415102
      WBVar01607465
      WBVar00879813
      WBVar01607466
      WBVar00879814
      WBVar01607467
      WBVar00879815
      WBVar00318591
      WBVar01607468
      WBVar00879816
      WBVar00879817
      WBVar01607469
      WBVar00879818
      WBVar01607470
      WBVar00879819
      WBVar00879820
      WBVar00879821
      WBVar00599561
      WBVar00879822
      WBVar01667610
      WBVar00879823
      WBVar00879824
      WBVar00879825
      WBVar00879826
      WBVar00879827
      WBVar00879828
      WBVar00879829
      WBVar00879830
      WBVar01893724
      WBVar00879831
      WBVar00879832
      WBVar00879833
      WBVar00879834
      WBVar00879835
      WBVar01802468
      WBVar00879836
      WBVar01984269
      WBVar00879837
      WBVar00879838
      WBVar01984270
      WBVar01984271
      WBVar00879839
      WBVar00879840
      WBVar00879841
      WBVar00879842
      WBVar00879843
      WBVar00879844
      WBVar00879845
      WBVar00879846
      WBVar01499608
      WBVar01500161
      WBVar00240234
      WBVar00322294
      WBVar01495198
      WBVar02068660
      WBVar00265464
      WBVar01499633
      WBVar01825532
      WBVar01825533
      WBVar00091912
      WBVar00260163
      WBVar00255204
      WBVar00249676
      WBVar01499498
      WBVar01499499
      WBVar00879740
      WBVar00879741
      WBVar00320439
      WBVar00879742
      WBVar00879743
      WBVar01996110
      WBVar00879744
      WBVar01996111
      WBVar00879745
      WBVar00879746
      WBVar00879747
      WBVar00879748
      WBVar00879749
      WBVar02148220
      WBVar00879750
      WBVar01499328
      WBVar00879751
      WBVar01499329
      WBVar02071708
      WBVar00879752
      WBVar01771557
      WBVar00879753
      WBVar00879754
    Strain: WBStrain00031528
    RNASeq_FPKM (74)
    GO_annotation: 00104971
      00104972
      00104973
      00104974
      00105059
      00122924
      00122925
      00122926
    Ortholog (30)
    Paralog: WBGene00001475 Caenorhabditis elegans From_analysis: Panther
      WBGene00001980 Caenorhabditis elegans From_analysis: Panther
      WBGene00022103 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000395 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000396 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000397 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000399 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000401 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000402 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00019994 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: cdh-8 encodes a cadherin that may be nematode specific; CDH-8 is predicted to function as a membrane protein that plays a role in cell adhesion and/or morphogenesis, but as loss of cdh-8 activity via mutation or large-scale RNAi experiments results in no obvious abnormalities, the precise role of cdh-8 in C. elegans development and/or behavior is not yet known. Paper_evidence: WBPaper00004508
            WBPaper00005654
            WBPaper00013424
            WBPaper00025054
          Curator_confirmed: WBPerson1843
          Date_last_updated: 09 Aug 2006 00:00:00
      Automated_description: Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in plasma membrane. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F18F11.3a
      F18F11.3b
      F18F11.3c
      F18F11.3d
      F18F11.3e
      F18F11.3f
      F18F11.3g
      F18F11.3h
      F18F11.3i
    Corresponding_CDS_history: F18F11.3:wp138
    Corresponding_transcript: F18F11.3a.1
      F18F11.3b.1
      F18F11.3c.1
      F18F11.3d.1
      F18F11.3e.1
      F18F11.3f.1
      F18F11.3g.1
      F18F11.3h.1
      F18F11.3i.1
    Other_sequence: JI251688.1
      Tcol_isotig19609
      GO240170.1
      CJC07964_1
    Associated_feature (11)
  Experimental_info: RNAi_result: WBRNAi00044964 Inferred_automatically: RNAi_primary
      WBRNAi00021256 Inferred_automatically: RNAi_primary
      WBRNAi00013523 Inferred_automatically: RNAi_primary
      WBRNAi00057962 Inferred_automatically: RNAi_primary
      WBRNAi00013522 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1019871
      Expr1037548
      Expr1148933
      Expr2009804
      Expr2028045
    Drives_construct: WBCnstr00027194
    Construct_product: WBCnstr00027194
    Microarray_results (39)
    Expression_cluster: WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00044260:1-methylnicotinamide_downregulated
      WBPaper00044260:nicotic-acid_downregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044760:somatic_specific
      WBPaper00045521:Spermatogenic
      WBPaper00045774:clk-1_downregulated
      WBPaper00047132:skn-1(RNAi)_downregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049377:MWCNT_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:stavudine_72h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053321:embryo-to-L1_downregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
      WBPaper00053321:mes-2(RNAi)_upregulated_fed-L1_Truseq
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053771:up_at_24h-NaCl
      WBPaper00053771:up_at_dpy-7(e88)
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055103:thoc-5(wy822)_upregulated
      WBPaper00055334:DLC-1_interacting
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055565:AVK_enriched
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056167:Cry5B_upregulated
      WBPaper00056169:rrf-3(pk1426)_downregulated_L3
      WBPaper00056169:rrf-3(pk1426)_downregulated_L4
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056169:rrf-3(pk1426)_upregulated_L2
      WBPaper00056284:ints-5(RNAi)_upregulated
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056330:glycine_downregulated
      WBPaper00056443:DietaryRestriction_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00057068:numr-1(RNAi)_downregulated
      WBPaper00057154:HeatShock_upregulated_mRNA
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058691:set-2(bn129)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059421:daf-3(mgDf90)_downregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059728:20ug_cholesterol_upregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060909:atfs-1(et18)_downregulated
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:AIB
      WBPaper00061340:ASG
      WBPaper00061340:CEPso
      WBPaper00061340:FLP
      WBPaper00061340:hyp1V_and_ant_arc_V
      WBPaper00061340:mc1
      WBPaper00061340:mc2
      WBPaper00061340:mc3
      WBPaper00061340:Neuroblast_AIZ_FLP
      WBPaper00061340:Pharyngeal_marginal_cell
      WBPaper00061340:RIC
      WBPaper00061340:RIC_parent
      WBPaper00061340:RMD
      WBPaper00061340:SIB
      WBPaper00061340:URX
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061527:srj-42-srw-113
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00062440:crh-1(syb385)_downregulated
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064505:tamoxifen_downregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
      WBPaper00064939:vit-5(RNAi)_upregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065560:E.coli-HB101_downregulated_F3
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065746:eat-2(ad1113)_downregulated
      WBPaper00065749:endu-2(tm4977)_upregulated
      WBPaper00065841:50_0
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4489_group_12
      cgc4489_group_20
      cgc4489_group_22
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-exposed_48h
      WBPaper00045294:50uM_DBAA_downregulated
      WBPaper00045807:microcystin-LR_downregulated
      WBPaper00046083:oga-1(ok1207)_OP50_downregulated
      WBPaper00046083:pmk-1(km25)_OP50_downregulated
      WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO
      WBPaper00056330:mrps-5(RNAi)_upregulated
    Interaction: WBInteraction000260252
      WBInteraction000286273
      WBInteraction000303796
      WBInteraction000313612
      WBInteraction000351359
      WBInteraction000352851
      WBInteraction000445411
      WBInteraction000585377
  Map_info: Map: IV Position: -26.4471 Error: 0.029965
    Positive: Positive_clone: F18F11 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5537
        4691
    Pseudo_map_position
  Reference: WBPaper00004508
    WBPaper00013424
    WBPaper00018119
    WBPaper00027233
    WBPaper00038491
    WBPaper00053755
    WBPaper00055090
    WBPaper00058555
    WBPaper00060859
    WBPaper00064138
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene