| WBGene00006741 | SMap | S_parent | Sequence | K03E6 |
|---|
| Identity | Version | 1 |
| | Name | CGC_name | unc-1 | Person_evidence | WBPerson261 |
| | | Sequence_name | K03E6.5 |
| | | Molecular_name | K03E6.5a |
| | | | K03E6.5a.1 |
| | | | CE28585 |
| | | | K03E6.5b |
| | | | CE42275 |
| | | | K03E6.5b.1 |
| | | Other_name | unc-102 |
| | | | CELE_K03E6.5 | Accession_evidence | NDB | BX284606 |
| | | Public_name | unc-1 |
| | DB_info | Database | AceView | gene | XB678 |
| | | | WormQTL | gene | WBGene00006741 |
| | | | WormFlux | gene | WBGene00006741 |
| | | | NDB | locus_tag | CELE_K03E6.5 |
| | | | Panther | gene | CAEEL|WormBase=WBGene00006741|UniProtKB=Q21190 |
| | | | | family | PTHR10264 |
| | | | NCBI | gene | 180458 |
| | | | RefSeq | protein | NM_001129690.5 |
| | | | | | NM_075801.7 |
| | | | SwissProt | UniProtAcc | Q21190 |
| | | | TrEMBL | UniProtAcc | G5ED08 |
| | | | UniProt_GCRP | UniProtAcc | Q21190 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:41 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | unc |
| | Allele (97) |
| | Legacy_information | lass 1 (loss-of-function) e719 : putative null recessive kinker. ES3 NA (recessive) > 10. unc-1 Class 3 (neomorph/antimorph) e94sd (former reference allele) : recessive kinker e94/+ is weak coiler ES2 ME2; e1598dm (pka unc-102) : both homozygote and e1598/+ are strong coilers resistant to aldicarb (cholinesterase inhibitor); intragenic revertants of e1598 have Class 1 phenotype. ES3 ME0. NA (dominant) > 8. Complex complementation among unc-1 alleles. |
| | | See unc-1. |
| | | See also e1598, e2380, e2381, n494, n496, n774, n775, n779, n782, n783, n784, n1166, n1167, n1200, n1201, n1202, n1203, n1204, n1205, n1206, n1207, n1208, n1209 |
| | | [C.elegansII] e719 : recessive kinker, putative null. Suppresses anaesthetic hypersensitivity of unc-79 and unc-80 mutants. ES3 ME1. OA>10(recessive): e50, e68, e114 (anomalous allele, transdominant suppressor of n494sd), etc. Also neomorph/antimorph gf alleles: e94sd (former reference allele, recessive kinker; e94/+ is weak coiler. ES2 ME2), e1598dm (pka unc-102, both homozygote and e1598/+ are strong Ric coilers; intragenic revertants of e1598 resemble e719. ES3 ME0). OA>8 (dominant and semidominant);n496, n775 (strongly dominant), n494 (weaklysemidominant), etc. Complex complementation among unc-1 alleles. [Park and Horvitz 1986a; Morgan and Sedensky 1994; CW] |
| | Strain (37) |
| | RNASeq_FPKM (74) |
| | GO_annotation (15) |
| | Ortholog (29) |
| | Paralog | WBGene00003166 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00006063 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00006064 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00006065 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00006066 | Caenorhabditis elegans | From_analysis | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00006067 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00006068 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00006761 | Caenorhabditis elegans | From_analysis | TreeFam |
| | | | | | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00006061 | Caenorhabditis elegans | From_analysis | WormBase-Compara |
| | Structured_description (2) |
| Molecular_info | Corresponding_CDS | K03E6.5a |
| | | K03E6.5b |
| | Corresponding_CDS_history | K03E6.5:wp188 |
| | Corresponding_transcript | K03E6.5a.1 |
| | | K03E6.5b.1 |
| | Other_sequence (59) |
| | Associated_feature | WBsf670099 |
| | | WBsf1003931 |
| | | WBsf1003932 |
| | | WBsf1022206 |
| | | WBsf1022207 |
| | | WBsf1022208 |
| | | WBsf236994 |
| | | WBsf236995 |
| | | WBsf236996 |
| Experimental_info | RNAi_result | WBRNAi00103042 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00049837 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Expr527 |
| | | Expr887 |
| | | Expr3407 |
| | | Expr4819 |
| | | Expr1022667 |
| | | Expr1032816 |
| | | Expr1153550 |
| | | Expr2017854 |
| | | Expr2035990 |
| | Drives_construct | WBCnstr00012258 |
| | | WBCnstr00012259 |
| | | WBCnstr00012423 |
| | | WBCnstr00014590 |
| | | WBCnstr00019884 |
| | | WBCnstr00034181 |
| | Construct_product | WBCnstr00012423 |
| | | WBCnstr00023065 |
| | | WBCnstr00034181 |
| | | WBCnstr00042106 |
| | Antibody | WBAntibody00000361 |
| | | WBAntibody00000750 |
| | | WBAntibody00001262 |
| | Microarray_results (22) |
| | Expression_cluster | WBPaper00005700:transmembrane_protein |
| | | WBPaper00032425:up_in_zfp-1 |
| | | WBPaper00033065:cyc-1(RNAi)_upregulated |
| | | WBPaper00037950:A-class-motor-neurons_larva_enriched |
| | | WBPaper00037950:all-neurons_larva_enriched |
| | | WBPaper00037950:dopaminergic-neurons_larva_enriched |
| | | WBPaper00037950:glr-1(+)-neurons_larva_enriched |
| | | WBPaper00037950:PVD-OLL-neurons_larva_enriched |
| | | WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray |
| | | WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray |
| | | WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray |
| | | WBPaper00044037:eat-2_upregulated |
| | | WBPaper00044501:gld-1_let-7_regulated |
| | | WBPaper00044656:tatn-1(qd182)_upregulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00045974:NSM_enriched_totalRNA_RNAseq |
| | | WBPaper00046497:B.thuringiensis_upregulated_protein |
| | | WBPaper00046795:starvation_upregulated |
| | | WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background |
| | | WBPaper00047131:daf-2(e1370)_upregulated_N2-background |
| | | WBPaper00048923:Aging_regulated |
| | | WBPaper00048988:neuron_enriched |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049545:jmjd-3.1(+)_upregulated |
| | | WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031) |
| | | WBPaper00049920:Glucose-Diet_upregulated_N2 |
| | | WBPaper00050053:muscle_enriched_Day4 |
| | | WBPaper00050332:skn-1(RNAi)_downregulated |
| | | WBPaper00050370:dpy-21(e428)_L3_upregulated |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_20C |
| | | WBPaper00050726:OsmoticStress_regulated_Food |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult |
| | | WBPaper00050990:arcade_intestinal-valve_expressed |
| | | WBPaper00050990:body-muscle_expressed |
| | | WBPaper00050990:GABAergic-neuron_expressed |
| | | WBPaper00050990:intestine_expressed |
| | | WBPaper00050990:NMDA-neuron_expressed |
| | | WBPaper00050990:seam_expressed |
| | | WBPaper00051245:body-wall-muscle_cytoplasm_expressed |
| | | WBPaper00051245:epidermis_cytoplasm_expressed |
| | | WBPaper00051245:intestine_cytoplasm_expressed |
| | | WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed |
| | | WBPaper00051437:Cit-SPIONs_downregulated |
| | | WBPaper00051461:pig-1(gm344)_downregulated |
| | | WBPaper00052884:emb-4(hc60)_upregulated |
| | | WBPaper00053184:sma-2(rax5)_upregulated |
| | | WBPaper00053184:sma-4(rax3)_upregulated |
| | | WBPaper00053302:stavudine_24h_regulated |
| | | WBPaper00053302:zidovudine_72h_regulated |
| | | WBPaper00053388:dauer_regulated_Cluster4 |
| | | WBPaper00053615:SMO-1_target |
| | | WBPaper00054758:alg-1(gk204)_upregulated |
| | | WBPaper00055060:flr-1(RNAi)_upregulated |
| | | WBPaper00055103:thoc-5(wy822)_upregulated |
| | | WBPaper00055354:eat-2(ad1116)_upregulated |
| | | WBPaper00055354:Psora-Allantoin_downregulated |
| | | WBPaper00055354:Rapamycin-Allantoin_downregulated |
| | | WBPaper00055354:Rapamycin-Metformin_downregulated |
| | | WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated |
| | | WBPaper00055354:Rifampicin-Allantoin_downregulated |
| | | WBPaper00055482:Tunicamycin_downregulated |
| | | WBPaper00055626:pry-1(mu38)_downregulated |
| | | WBPaper00055648:male-tail_expressed |
| | | WBPaper00055827:pfd-6(gk493446)_downregulated |
| | | WBPaper00055971:nhl-2(ok818)_25C_downregulated |
| | | WBPaper00056034:pals-22(jy3)_upregulated |
| | | WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047) |
| | | WBPaper00056090:E.faecalis_upregulated_N2 |
| | | WBPaper00056443:sek-1(km4)_upregulated |
| | | WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated |
| | | WBPaper00056826:hmc_biased |
| | | WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C |
| | | WBPaper00058598:mex-1(or286)_upregulated |
| | | WBPaper00058598:mex-3(eu149)_upregulated |
| | | WBPaper00058598:sin-3(tm1276)_downregulated |
| | | WBPaper00058598:spn-4(tm291)_upregulated |
| | | WBPaper00058691:cfp-1(tm6369)_upregulated |
| | | WBPaper00058691:set-2(bn129)_upregulated |
| | | WBPaper00058691:sin-3(tm1276)_upregulated |
| | | WBPaper00058711:skn-1(lax188)_upregulated |
| | | WBPaper00058948:PA14_downregulated |
| | | WBPaper00059027:neuron-synapses_depleted |
| | | WBPaper00059356:BAZ-2_SET-6_interacting |
| | | WBPaper00059421:daf-3(mgDf90)_downregulated |
| | | WBPaper00059471:EGL-43_interacting |
| | | WBPaper00059664:srbc-48(ac23)_upregulated |
| | | WBPaper00059763:neuron_expressed |
| | | WBPaper00060014:set-2(tm1630)_downregulated |
| | | WBPaper00060459:bcat-1(RNAi)_upregulated |
| | | WBPaper00060661:sensory-neuron_enriched |
| | | WBPaper00060811:L1_vs_adult_upregulated_neural |
| | | WBPaper00061007:S.aquatilis_upregulated |
| | | WBPaper00061203:sin-3(tm1276)_upregulated |
| | | WBPaper00061203:spr-1(ok2144)_upregulated |
| | | WBPaper00061210:huIs179_upregulated |
| | | WBPaper00061274:hypergravity_10xg_upregulated |
| | | WBPaper00061274:microgravity_downregulated |
| | | WBPaper00061340:AIB |
| | | WBPaper00061340:AIM |
| | | WBPaper00061340:AIZ |
| | | WBPaper00061340:ALN |
| | | WBPaper00061340:AVB |
| | | WBPaper00061340:AVD |
| | | WBPaper00061340:AVG |
| | | WBPaper00061340:AVL |
| | | WBPaper00061340:DA |
| | | WBPaper00061340:DA_DB |
| | | WBPaper00061340:DB |
| | | WBPaper00061340:DD |
| | | WBPaper00061340:DVA |
| | | WBPaper00061340:DVC |
| | | WBPaper00061340:FLP |
| | | WBPaper00061340:hmc |
| | | WBPaper00061340:IL1 |
| | | WBPaper00061340:mu_int_mu_anal |
| | | WBPaper00061340:mu_sph |
| | | WBPaper00061340:OLL |
| | | WBPaper00061340:PVP |
| | | WBPaper00061340:PVT |
| | | WBPaper00061340:RIA |
| | | WBPaper00061340:RIB |
| | | WBPaper00061340:RIC |
| | | WBPaper00061340:RIM |
| | | WBPaper00061340:RMD |
| | | WBPaper00061340:RME |
| | | WBPaper00061340:SMB |
| | | WBPaper00061340:SMD |
| | | WBPaper00061405:S.aureus_downregulated_starvation |
| | | WBPaper00061424:Diet_MYb120_upregulated |
| | | WBPaper00061479:hda-1(ne4752)_upregulated |
| | | WBPaper00061527:syd-1_2945-unc-41_2170 |
| | | WBPaper00061651:AIZ_enriched |
| | | WBPaper00061651:DA_enriched |
| | | WBPaper00061651:DB01_enriched |
| | | WBPaper00061651:DB_enriched |
| | | WBPaper00061651:I3_enriched |
| | | WBPaper00061651:I4_enriched |
| | | WBPaper00061651:M2_enriched |
| | | WBPaper00061651:NSM_enriched |
| | | WBPaper00061651:PDA_enriched |
| | | WBPaper00061651:PDB_enriched |
| | | WBPaper00061651:RIG_enriched |
| | | WBPaper00061651:VA12_enriched |
| | | WBPaper00061651:VB01_enriched |
| | | WBPaper00061651:VB_enriched |
| | | WBPaper00061995:mter-4(syb3662syb3403)_downregulated |
| | | WBPaper00062103:neuron_enriched |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062193:skn-1(RNAi)_upregulated |
| | | WBPaper00062325:muscle_enriched_coding-RNA |
| | | WBPaper00062554:MAGU-2_interacting |
| | | WBPaper00064071:NHR-49_interacting |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064156:lipl-4(overexpress)_upregulated |
| | | WBPaper00064306:Agaro-oligosaccharides_upregulated |
| | | WBPaper00064721:fasn-1(g14)_downregulated_starved |
| | | WBPaper00065096:25C_vs_20C_downregulated |
| | | WBPaper00065096:Day10_vs_Day1_downregulated |
| | | WBPaper00065120:body-muscle-transcriptome |
| | | WBPaper00065158:25C_vs_15C_upregulated_AFD |
| | | WBPaper00065373:Cisplatin_downregulated_WT |
| | | WBPaper00065560:E.coli-HB101_downregulated_F3 |
| | | WBPaper00065581:hpk-1(pk1393)_upregulated |
| | | WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977) |
| | | WBPaper00065749:Heat-Shock_downregulated_N2 |
| | | WBPaper00065835:Day5_vs_Day1_downregulated |
| | | WBPaper00065835:Day11_vs_Day1_downregulated |
| | | WBPaper00065841:65_0 |
| | | WBPaper00065841:132_0 |
| | | WBPaper00066110:Doxorubicin_upregulated_diploid |
| | | WBPaper00066110:tetraploid_vs_diploid_upregulated |
| | | cgc4386_cluster_6_5 |
| | | cgc4489_group_14 |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Enriched_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00030839:Embryo_A_Class |
| | | WBPaper00030839:Embryo_Pan_Neuronal |
| | | WBPaper00030839:Larval_Pan_Neuronal |
| | | WBPaper00031003:hlh_1_enriched |
| | | WBPaper00031532:Larva_Pan_Neuronal_Enriched |
| | | WBPaper00035588:alg-1(-)_upregulated |
| | | WBPaper00035873:dpy-9_regulated |
| | | WBPaper00035873:dpy-10_regulated |
| | | WBPaper00036123:Atrazine_regulated |
| | | WBPaper00036286:Pattern_C |
| | | WBPaper00037695:WC_5-day |
| | | WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated |
| | | WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2 |
| | | WBPaper00040858:eQTL_age_regulated_developing |
| | | WBPaper00040876:mir-35_downregulated |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_51h |
| | | WBPaper00041939:control_vs_UVC-exposed_3h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h |
| | | WBPaper00042274:tbx-2(bx59)_upregulated |
| | | WBPaper00045673:colistin_upregulated |
| | | WBPaper00057098:SiO2-nanoparticles_upregulated |
| | Interaction (129) |
| Map_info | Map | X | Position | -18.7759 | Error | 0.006952 |
| | Well_ordered |
| | Positive | Inside_rearr | mnDp69 |
| | | | meDf3 |
| | | | meDf5 |
| | | | mnDp52 |
| | | | yDp13 |
| | | | yDp15 |
| | | | meDf2 |
| | | | meDf6 |
| | | Positive_clone | C04D1 |
| | | | K03E6 | Author_evidence | (rescues when |
| | | | | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Negative | Negative_clone | C55D6 |
| | | | T17A11 |
| | Mapping_data | 2_point (12) |
| | | Multi_point (38) |
| | | Pos_neg_data (46) |
| | Landmark_gene |
| Reference (109) |
| Method | Gene |
