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WormBase Tree Display for Gene: WBGene00020455

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Name Class

WBGene00020455SMapS_parentSequenceT12B5
IdentityVersion2
NameCGC_namefbxa-59Person_evidenceWBPerson655
Sequence_nameT12B5.8
Molecular_nameT12B5.8
T12B5.8.1
CE32934
T12B5.8.2
Other_nameCELE_T12B5.8Accession_evidenceNDBBX284603
Public_namefbxa-59
DB_infoDatabaseAceViewgene3B556
WormQTLgeneWBGene00020455
WormFluxgeneWBGene00020455
NDBlocus_tagCELE_T12B5.8
PanthergeneCAEEL|WormBase=WBGene00020455|UniProtKB=Q9TZ27
familyPTHR23015
NCBIgene188447
RefSeqproteinNM_001384021.1
TREEFAMTREEFAM_IDTF322360
TrEMBLUniProtAccQ9TZ27
UniProt_GCRPUniProtAccQ9TZ27
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:03WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
212 Dec 2005 15:18:56WBPerson2970Name_changeCGC_namefbxa-59
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classfbxa
AlleleWBVar02100170
WBVar02089498
WBVar00800408
WBVar00800409
WBVar02122810
WBVar00800410
WBVar00800411
WBVar00800412
WBVar02121157
WBVar02124101
WBVar00800413
WBVar02121158
WBVar01577862
WBVar00800414
WBVar02094106
WBVar02087850
WBVar02094107
WBVar02087851
WBVar00800415
WBVar01577863
WBVar01577864
WBVar00800416
WBVar02120976
WBVar02094108
WBVar00800417
WBVar01577865
WBVar02120977
WBVar02120978
WBVar00800418
WBVar01577866
WBVar01577867
WBVar01606485
WBVar00800419
WBVar02122452
WBVar02120979
WBVar02122453
WBVar01577868
WBVar01606486
WBVar00800420
WBVar01500082
WBVar02120980
WBVar00032913
WBVar00800421
WBVar01606487
WBVar02120981
WBVar01606488
WBVar02120982
WBVar00800422
WBVar01606489
WBVar00800423
WBVar02120983
WBVar02120984
WBVar01606490
WBVar00032918
WBVar02123377
WBVar00800424
WBVar00800425
WBVar01606491
WBVar00800426
WBVar01540535
WBVar00800427
WBVar01540536
WBVar00032923
WBVar00800428
WBVar01823221
WBVar01540537
WBVar01540538
WBVar00559525
WBVar01823222
WBVar00800429
WBVar01540539
WBVar00032928
WBVar00559526
WBVar00800430
WBVar01540540
WBVar02099459
WBVar00559527
WBVar00800431
WBVar01540541
WBVar00800432
WBVar00559530
WBVar01540542
WBVar00800433
WBVar00032933
WBVar00559531
WBVar00800434
WBVar01627685
WBVar01540543
WBVar00800435
WBVar01627686
WBVar01540544
WBVar01627687
WBVar00032938
WBVar00800436
WBVar00800437
WBVar01627688
WBVar00800438
WBVar01627689
WBVar01627690
WBVar00032943
WBVar00388949
WBVar01627691
WBVar00388950
WBVar02123578
WBVar00388951
WBVar00032948
WBVar01499552
WBVar00388952
WBVar00388953
WBVar00388954
WBVar02101312
WBVar02124686
WBVar00388955
WBVar00032953
WBVar02101313
WBVar02121742
WBVar02101314
WBVar02123217
WBVar00032958
WBVar01852188
WBVar00032963
WBVar01785056
WBVar02122116
WBVar01852189
WBVar01852190
WBVar00032968
WBVar01852191
WBVar01852192
WBVar01852193
WBVar02120832
WBVar01852194
WBVar00032973
WBVar01498832
WBVar01852195
WBVar02103167
WBVar01852196
WBVar00032978
WBVar01852197
WBVar01852198
WBVar01852199
WBVar00095528
WBVar00032983
WBVar01721647
WBVar01852200
WBVar01852201
WBVar01721648
WBVar01852202
WBVar01721649
WBVar02120474
WBVar01852203
WBVar00032988
WBVar01852204
WBVar02124343
WBVar02121583
WBVar02111280
WBVar02120666
WBVar01693968
WBVar02121404
WBVar02124181
WBVar02121974
WBVar01322820
WBVar01564564
WBVar01322821
WBVar01564565
WBVar01322822
WBVar01322823
WBVar01322824
WBVar01322825
WBVar01983524
WBVar01322826
WBVar01322827
WBVar02092354
WBVar01322828
WBVar01322830
WBVar01322831
WBVar01322833
WBVar02100638
WBVar01322834
WBVar01401011
WBVar02100639
WBVar01322835
WBVar01912605
WBVar01322836
WBVar02102113
WBVar01692159
WBVar01322837
WBVar01322839
WBVar02102114
WBVar01506265
WBVar01322841
WBVar01908359
WBVar01827007
WBVar01506266
WBVar01322842
WBVar01908360
WBVar01506267
WBVar01322843
WBVar01827008
WBVar01322844
WBVar01506268
WBVar01827009
WBVar01506269
WBVar01322845
WBVar01827010
WBVar01322846
WBVar01506270
WBVar01827011
WBVar01827012
WBVar01506271
WBVar01322848
WBVar01322849
WBVar01827013
WBVar01506272
WBVar01643318
WBVar01322850
WBVar01643319
WBVar01322852
WBVar01255524
WBVar02117033
WBVar01643320
WBVar01322853
WBVar01643321
WBVar01255525
WBVar02117034
WBVar01322854
WBVar01322858
WBVar01255526
WBVar01643322
WBVar01255527
WBVar01322859
WBVar01255528
WBVar01322861
WBVar02122375
WBVar02122559
WBVar01322865
WBVar01255530
WBVar01322869
WBVar02124401
WBVar01255531
WBVar02124953
WBVar02012672
WBVar02124954
WBVar01255533
WBVar01407372
WBVar01255534
WBVar01255535
WBVar01255539
WBVar02122933
WBVar01415196
WBVar01255541
WBVar01951284
WBVar02123672
WBVar01255544
WBVar01951285
WBVar02124779
WBVar01685930
WBVar01685931
WBVar01685932
WBVar02030213
WBVar02030214
WBVar01488984
WBVar02086511
WBVar01769481
WBVar02014585
WBVar01769482
WBVar01769483
WBVar01769484
WBVar01700502
WBVar01769485
WBVar01700503
WBVar01937796
WBVar01700504
WBVar01898622
WBVar01700505
WBVar02057248
WBVar01898623
WBVar00007891
WBVar00007896
WBVar01706435
WBVar01706436
WBVar00258335
WBVar00007901
WBVar01706437
WBVar01706438
WBVar01706439
WBVar00007906
WBVar02121865
WBVar02118922
WBVar00007911
WBVar02111563
WBVar01389906
WBVar01893054
WBVar01389907
WBVar01389909
WBVar00269528
WBVar00269529
WBVar01389930
WBVar02097766
WBVar00269530
WBVar00269532
WBVar00269533
WBVar00269534
WBVar00269535
WBVar01548339
WBVar01548340
WBVar00269536
WBVar02081394
WBVar00269537
WBVar02081395
WBVar01548341
WBVar02081396
WBVar01548342
WBVar00269538
WBVar00269539
WBVar01548343
WBVar00269540
WBVar01896258
WBVar00269541
WBVar01896259
WBVar01896260
WBVar00269542
RNASeq_FPKM (74)
GO_annotation00097797
Ortholog (36)
Paralog (222)
Structured_descriptionConcise_descriptionThis gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.Paper_evidenceWBPaper00012854
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionInvolved in innate immune response.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDST12B5.8
Corresponding_CDS_historyT12B5.8:wp91
Corresponding_transcriptT12B5.8.1
T12B5.8.2
Experimental_infoRNAi_resultWBRNAi00018634Inferred_automaticallyRNAi_primary
WBRNAi00018636Inferred_automaticallyRNAi_primary
WBRNAi00007152Inferred_automaticallyRNAi_primary
WBRNAi00053194Inferred_automaticallyRNAi_primary
WBRNAi00035507Inferred_automaticallyRNAi_primary
WBRNAi00023592Inferred_automaticallyRNAi_primary
WBRNAi00053193Inferred_automaticallyRNAi_primary
WBRNAi00006642Inferred_automaticallyRNAi_primary
Expr_patternExpr1156784
Expr2011559
Expr2029797
Drives_constructWBCnstr00025125
Construct_productWBCnstr00025125
Microarray_results (13)
Expression_clusterWBPaper00024505:pharyngeal_enriched
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00037950:all-neurons_embryo_enriched
WBPaper00037950:dopaminergic-neurons_larva_enriched
WBPaper00037950:intestine_CoreEnriched
WBPaper00037950:intestine_embryo_enriched
WBPaper00037950:intestine_larva_enriched
WBPaper00037950:PVD-OLL-neurons_larva_enriched
WBPaper00038168:lin-15B(n744)_upregulated
WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
WBPaper00042215:wdr-23(tm1817)_upregulated
WBPaper00042561:smgl-1(RNAi)_upregulated
WBPaper00044037:eat-2_upregulated
WBPaper00044260:1-methylnicotinamide_downregulated
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044736:flat_dev_expression
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
WBPaper00045050:csr-1(hypomorph)_upregulated
WBPaper00045314:S.aureus-induced_hlh-30(tm1978)
WBPaper00045314:S.aureus-induced_N2
WBPaper00045316:prg-1_upregulated_L4
WBPaper00045486:starvation_downregulated
WBPaper00045934:wrn-1(gk99)_downregulated
WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
WBPaper00047131:daf-2(e1370)_upregulated_N2-background
WBPaper00048971:daf-16(mgDf50)_downregulated_L1
WBPaper00048988:neuron_expressed
WBPaper00049018:ham-3(RNAi)_downregulated
WBPaper00049018:swsn-2.2(RNAi)_downregulated
WBPaper00049217:TCER-1_downregulated
WBPaper00049334:CE_intestine_enriched
WBPaper00049498:npr-1(ur89)_regulated_5
WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
WBPaper00049942:hsf-1(RNAi)_upregulated
WBPaper00049954:BPA_upregulated
WBPaper00050080:rbr-2(tm3141)_upregulated
WBPaper00050096:P.aeruginosa_upregulated
WBPaper00050121:mir-60(n4947)_upregulated
WBPaper00050344:AFD-neuron_enriched
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050504:hrp-2(RNAi)_upregulated
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050990:body-muscle_expressed
WBPaper00050990:intestine_expressed
WBPaper00051039:intestine_enriched
WBPaper00051558:aging_regulated
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053020:sid-3(ok973)_upregulated
WBPaper00053020:sta-1(ok587)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053295:lin-22(ot269)_upregulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053388:dauer_regulated_Cluster6
WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_doenregulated
WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
WBPaper00053810:daf-2(e1370)_upregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00055060:flr-1(RNAi)_upregulated
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Metformin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055354:Rifampicin_downregulated
WBPaper00055386:eat-2(ad465)_upregulated
WBPaper00055626:pry-1(mu38)_downregulated
WBPaper00055827:daf-2(e1370)_upregulated
WBPaper00055941:atfs-1(et15)_upregulated
WBPaper00055941:nuo-6(qm200)_upregulated
WBPaper00055971:nhl-2(ok818)_25C_downregulated
WBPaper00056034:pals-22(jy3)_upregulated
WBPaper00056034:pals-25(jy9)_upregulated
WBPaper00056039:efa-6(tm3124)_upregulated
WBPaper00056073:R24_upregulated_nhr-86_dependent
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_upregulated_N2
WBPaper00056167:Cry5B_downregulated
WBPaper00056167:ifo-1(kc2)_downregulated
WBPaper00056275:P.aeruginosa_upregulated
WBPaper00056284:ints-1(RNAi)_upregulated
WBPaper00056290:hsp-6(mg585)_upregulated
WBPaper00056330:glycine_downregulated
WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1
WBPaper00056586:kri-1(ok1251)_upregulated
WBPaper00056826:SGP_biased
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057006:DietaryRestriction_downregulated
WBPaper00057068:Cadmium_upregulated
WBPaper00057154:HeatShock_upregulated_mRNA
WBPaper00058598:mex-1(or286)_upregulated
WBPaper00058598:mex-3(eu149)_upregulated
WBPaper00058598:spn-4(tm291)_upregulated
WBPaper00058691:cfp-1(tm6369)_upregulated
WBPaper00058711:paraquat_downregulated
WBPaper00058711:skn-1(lax188)_upregulated
WBPaper00058948:PA14_downregulated
WBPaper00059373:stt-3(RNAi)_upregulated
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059739:hira-1(gk835598)_upregulated_adult
WBPaper00059824:rnp-6(dh1127)_regulated_OP50
WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
WBPaper00059839:S.maltophilia_regulated
WBPaper00059987:Wounding_upregulated
WBPaper00060273:isp-1(qm150)_upregulated
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060399:CoCl2_6hr_upregulated_N2
WBPaper00060526:plp-1(ok2155)_downregulated
WBPaper00060661:hypoxia_upregulated
WBPaper00060683:hlh-11(ko1)_upregulated
WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
WBPaper00061007:HB101_upregulated
WBPaper00061007:S.aquatilis_upregulated
WBPaper00061007:X.citri_upregulated
WBPaper00061081:E.faecalis_upregulated_N2
WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
WBPaper00061340:g1A
WBPaper00061341:28C_24h_upregulated
WBPaper00061341:28C_48h_upregulated
WBPaper00061527:F58F9.3_11574-R07B7.6
WBPaper00061530:nhr-49(e2144)_upregulated
WBPaper00061753:csr-1(tor159)_upregulated_25C
WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
WBPaper00062146:MOG-7-degron_1h_regulated
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062184:PA14_upregulated
WBPaper00062193:skn-1(RNAi)_downregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062440:crh-1(n3315)_downregulated
WBPaper00062440:crh-1(syb385)_downregulated
WBPaper00062446:nhr-8(hd117)_upregulated
WBPaper00062590:Aging_upregulated_coelomocyte
WBPaper00064005:starvation_upregulated_N2_mRNA
WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064156:lbp-3(overexpress)_upregulated
WBPaper00064156:lipl-4(overexpress)_upregulated
WBPaper00064539:nhr-114(gk849)_upregulated
WBPaper00064637:cox-5B(RNAi)_upregulated
WBPaper00064871:PA14_upregulated_AWA
WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
WBPaper00064939:vit-5(RNAi)_upregulated
WBPaper00065029:cadmium_upregulated
WBPaper00065086:JU1400_N.ferruginous_regulated
WBPaper00065086:JU1400_N.ironsii_regulated
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065392:Lb.rhamnosus_upregulated
WBPaper00065734:unc-25(e156)_upregulated
WBPaper00065749:endu-2(tm4977)_upregulated
WBPaper00065749:Heat-Shock-With-Recovery_upregulated_N2
WBPaper00065749:Heat-Shock_upregulated_endu-2(tm4977)
WBPaper00065835:Day5_vs_Day1_upregulated
WBPaper00065835:Day11_vs_Day1_upregulated
WBPaper00065841:3_4
WBPaper00065841:30_0
WBPaper00065841:30_3
WBPaper00065841:48_0
WBPaper00065841:57_0
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066110:tetraploid_vs_diploid_upregulated
WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
WBPaper00066232:hsf-1(RNAi)_upregulated_WT
cgc4489_group_3
WBPaper00005124:cholesterol_10-9M_regulated
WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
WBPaper00025141:N2_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00027111:eri-1(mg366)_upregulated
WBPaper00027111:rde-3(r459)_downregulated
WBPaper00027111:rde-3(r459)_upregulated
WBPaper00028482:PA14_upregulated
WBPaper00028789:PA14_vs_OP50_upregulated_8hr
WBPaper00029437:dcr-1_upregulated
WBPaper00029437:rde-4_upregulated
WBPaper00031003:24hr_muscle_enriched
WBPaper00031003:total_muscle_enriched
WBPaper00034661:AgNPs_downregulated
WBPaper00034739:N2moreDR1350
WBPaper00034739:RIL17moreRIL14
WBPaper00034757:up_by_oxidative_stress
WBPaper00035227:heat_shock_regulated
WBPaper00035873:dpy-10_regulated
WBPaper00036286:Pattern_D
WBPaper00037695:WC_5-day
WBPaper00037704:ABZ_up_regulated
WBPaper00038172:tax-6null_up_regulated
WBPaper00039851:HK_C_albicans_vs_HK_OP50
WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
WBPaper00040858:eQTL_age_regulated_aging
WBPaper00040858:eQTL_age_regulated_developing
WBPaper00040858:eQTL_regulated_aging
WBPaper00040858:eQTL_regulated_juvenile
WBPaper00040858:eQTL_regulated_old
WBPaper00040858:eQTL_regulated_reproductive
WBPaper00040963:TA100_up
WBPaper00040963:TA200_up
WBPaper00040963:TA300_up
WBPaper00041002:HQ_3d_2.0mM_Up
WBPaper00041207:CE_dauer_up
WBPaper00041370:spg-7(RNAi)_upregulated
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_EtBr-exposed_51h
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041939:control_vs_UVC-exposed_51h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
WBPaper00041960:N2_fasting_upregulated_anytime
WBPaper00042331:a-SWCNTs_downregulated
WBPaper00044091:Bpseudomallei_induced_4h
WBPaper00044091:Bpseudomallei_induced_8h
WBPaper00044091:Bpseudomallei_induced_12h
WBPaper00045263:0.1mM-paraquat_downregulated
WBPaper00045673:colistin_upregulated
WBPaper00045960:L4-lethargus_upregulated
WBPaper00047070:xpa-1_UV_upregulated
WBPaper00050515:nipi-3(fr4)_upregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
WBPaper00056330:mrps-5(RNAi)_upregulated
[cgc6390]:Cluster_B
Interaction (19)
Map_infoMapIIIPosition-25.0692Error0.004294
PositivePositive_cloneT12B5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00012854
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene