WormBase Tree Display for Expression_cluster: WBPaper00040858:eQTL_regulated_aging
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WBPaper00040858:eQTL_regulated_aging | Description | Genes with expression level regulated by genotype (N2 vs CB4856) at old adults stage (214 hours at 24 centigrade). | |
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Species | Caenorhabditis elegans | ||
Algorithm | For model 2, authors used 100 permutations to estimate the FDR threshold. Per permutation, genotypes and ages were independently randomly distributed, keeping the among-gene structure intact. Then for each spot (23,232) on the array, model 2 was tested. The obtained P-values were used to estimate a threshold for each of the explanatory factors. Authors also used a genome-wide threshold of -log10 P-value = 2, which resembles an FDR of 0.072 and 0.060 for marker and the interaction age-marker for the developing worms and FDR of 0.050 and 0.065 for marker and age-marker for the aging worms. For the physiological age effect, authors used a log10 P-value = 8 in developing worms (0.012 FDR) and -log10 P-value = 6 (0.032 FDR). | ||
Reference | WBPaper00040858 | ||
Microarray_results (2067) | |||
Gene (1798) | |||
Attribute_of | Microarray_experiment (14) | ||
Associated_with | Life_stage | WBls:0000070 |