| WBGene00003588 | SMap | S_parent | Sequence | ZC155 |
|---|
| Identity | Version | 1 |
| | Name | CGC_name | nex-1 |
| | | Sequence_name | ZC155.1 |
| | | Molecular_name | ZC155.1 |
| | | | ZC155.1.1 |
| | | | CE01431 |
| | | Other_name | CELE_ZC155.1 | Accession_evidence | NDB | BX284603 |
| | | Public_name | nex-1 |
| | DB_info | Database | AceView | gene | 3G315 |
| | | | WormQTL | gene | WBGene00003588 |
| | | | WormFlux | gene | WBGene00003588 |
| | | | NDB | locus_tag | CELE_ZC155.1 |
| | | | Panther | gene | CAEEL|WormBase=WBGene00003588|UniProtKB=G5EEA8 |
| | | | | family | PTHR10502 |
| | | | NCBI | gene | 175714 |
| | | | RefSeq | protein | NM_065708.10 |
| | | | TrEMBL | UniProtAcc | G5EEA8 |
| | | | UniProt_GCRP | UniProtAcc | G5EEA8 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | nex |
| | Allele (23) |
| | Legacy_information | [C.elegansII] NMK. Encodes protein with 42% identity to bovine annexin IV. Antibody stains pharyngeal grinder, gland cells, spermathecal folds. [CGC] |
| | Strain | WBStrain00035608 |
| | RNASeq_FPKM (74) |
| | GO_annotation (19) |
| | Ortholog (33) |
| | Paralog | WBGene00003589 | Caenorhabditis elegans | From_analysis | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00003590 | Caenorhabditis elegans | From_analysis | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00003591 | Caenorhabditis elegans | From_analysis | WormBase-Compara |
| | Structured_description | Concise_description | nex-1 encodes an annexin, a member of a family of calcium-dependent phospholipid binding proteins; NEX-1 is required for efficient engulfment of apoptotic cell corpses in the pharynx, and may also function in other membrane fusion events, such as exocytosis; NEX-1 in vitro can bind phosphatidylserine, phosphatidylinositol, heparin, heparan sulfate, and chondroitin sulfate; NEX-1 is expressed in the pharynx, hypodermal cells, the vulva, the uterus, the spermathecal valve, and yolk granules of maturing oocytes. | Paper_evidence | WBPaper00003602 |
| | | | | | WBPaper00004309 |
| | | | | | WBPaper00005874 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | Date_last_updated | 17 Jun 2004 00:00:00 |
| | | Automated_description | Enables heparin binding activity and phospholipid binding activity. Involved in engulfment of apoptotic cell. Located in intracellular membrane-bounded organelle and plasma membrane. Expressed in hypodermis; pharynx; spermathecal-uterine junction; uterine toroidal epithelial cell; and vulva. | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | ZC155.1 |
| | Corresponding_transcript | ZC155.1.1 |
| | Other_sequence (118) |
| | Associated_feature | WBsf654958 |
| | | WBsf717068 |
| | | WBsf717895 |
| | | WBsf992337 |
| | | WBsf1014858 |
| | | WBsf224881 |
| Experimental_info | RNAi_result | WBRNAi00107729 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00087553 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00067291 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00027665 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00021578 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00080498 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00005118 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00107730 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00058747 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00041886 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Expr1209 |
| | | Expr1210 |
| | | Expr1560 |
| | | Expr8283 |
| | | Expr1022217 |
| | | Expr1031638 |
| | | Expr1162168 |
| | | Expr2013979 |
| | | Expr2032219 |
| | Drives_construct | WBCnstr00010152 |
| | | WBCnstr00036022 |
| | Construct_product | WBCnstr00036022 |
| | Antibody | WBAntibody00000107 |
| | | WBAntibody00001198 |
| | Microarray_results (24) |
| | Expression_cluster | WBPaper00006195:azacoprostane_downregulated |
| | | WBPaper00024704:Soluble_protein |
| | | WBPaper00025192:hda-1(RNAi)_upregulated |
| | | WBPaper00028451:Abundant_spermatogenesis_enriched |
| | | WBPaper00031040:Cluster_5 |
| | | WBPaper00031040:TGF-beta_adult_upregulated |
| | | WBPaper00032528:L3_enriched |
| | | WBPaper00035073:mitochondria_protein |
| | | WBPaper00035926:A.hydrophila_regulated |
| | | WBPaper00036662:oxidative_modification |
| | | WBPaper00037950:A-class-motor-neurons_L2-larva_expressed |
| | | WBPaper00037950:excretory-cell_larva_enriched |
| | | WBPaper00037950:excretory-cell_larva_SelectivelyEnriched |
| | | WBPaper00037950:GABAergic-motor-neurons_larva_SelectivelyEnriched |
| | | WBPaper00037950:germline-precursors_embryo_enriched |
| | | WBPaper00037950:germline-precursors_embryo_SelectivelyEnriched |
| | | WBPaper00038213:E.coli(LF82)_72h_upregulated |
| | | WBPaper00038289:oocyte_protein |
| | | WBPaper00038438:Harposporium_24hr_downregulated_RNAseq |
| | | WBPaper00044128:DietaryRestriction_upregulated |
| | | WBPaper00044448:CholesterolStarvation_upregulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00044746:aging_upregulated_Day5 |
| | | WBPaper00044746:aging_upregulated_HeatShock |
| | | WBPaper00045316:prg-1_upregulated_L3 |
| | | WBPaper00045521:Gender_Neutral |
| | | WBPaper00046217:mev-1(kn1)_upregulated |
| | | WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h |
| | | WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h |
| | | WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h |
| | | WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h |
| | | WBPaper00046497:B.thuringiensis_upregulated_protein |
| | | WBPaper00046741:Garlic-Extract_upregulated_protein |
| | | WBPaper00048923:Aging_regulated |
| | | WBPaper00048988:daf-16(mu86)_downregulated_neuron |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049083:post-dauer-development_upregulated |
| | | WBPaper00049545:jmjd-3.1(+)_downregulated |
| | | WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated |
| | | WBPaper00049595:P.aeruginosa_48h_downregulated |
| | | WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031) |
| | | WBPaper00049920:Glucose-Diet_upregulated_N2 |
| | | WBPaper00050344:AFD-neuron_enriched |
| | | WBPaper00050344:ASER-neuron_enriched |
| | | WBPaper00050448:KGB-1-induced |
| | | WBPaper00050468:hlh-30-dependent_Cry5B_regulated |
| | | WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C |
| | | WBPaper00050599:nicotine(0.01mM)_upregulated |
| | | WBPaper00050801:DAF-12_dauer_regulome |
| | | WBPaper00050801:DAF-16_dauer_regulome |
| | | WBPaper00050801:DPY-21_dauer_regulome |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult |
| | | WBPaper00050903:mir-35-41(nDf50)_25C_upregulated |
| | | WBPaper00050990:arcade_intestinal-valve_expressed |
| | | WBPaper00050990:body-muscle_expressed |
| | | WBPaper00050990:GABAergic-neuron_expressed |
| | | WBPaper00050990:hypodermis_expressed |
| | | WBPaper00050990:intestine_expressed |
| | | WBPaper00050990:NMDA-neuron_expressed |
| | | WBPaper00050990:pharynx_expressed |
| | | WBPaper00050990:seam_expressed |
| | | WBPaper00051039:germline_enriched |
| | | WBPaper00051245:body-wall-muscle_cytoplasm_expressed |
| | | WBPaper00051245:body-wall-muscle_nucleus_expressed |
| | | WBPaper00051245:cytoplasm_specific |
| | | WBPaper00051245:epidermis_cytoplasm_expressed |
| | | WBPaper00051245:epidermis_nucleus_expressed |
| | | WBPaper00051245:intestine_cytoplasm_expressed |
| | | WBPaper00051245:intestine_nucleus_expressed |
| | | WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed |
| | | WBPaper00051245:pharyngeal-muscle_nucleus_expressed |
| | | WBPaper00051265:F4_morc-1(tm6048)_downregulated |
| | | WBPaper00051558:aging_regulated |
| | | WBPaper00053184:sma-2(rax5)_upregulated |
| | | WBPaper00053184:sma-4(rax3)_upregulated |
| | | WBPaper00053388:dauer_regulated_Cluster4 |
| | | WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated |
| | | WBPaper00053606:N2_vs_elt-2(ca15)_upregulated |
| | | WBPaper00053615:SMO-1_target |
| | | WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated |
| | | WBPaper00053771:up_at_3h-NaCl |
| | | WBPaper00053810:daf-2(e1370)_upregulated |
| | | WBPaper00053810:nuo-6(qm200)_upregulated |
| | | WBPaper00053814:25C_upregulated_OP50 |
| | | WBPaper00053814:25C_upregulated_PY79 |
| | | WBPaper00055049:S.gordonii_upregulated |
| | | WBPaper00055354:eat-2(ad1116)_downregulated |
| | | WBPaper00055354:Psora-Allantoin_downregulated |
| | | WBPaper00055354:Rapamycin-Allantoin_downregulated |
| | | WBPaper00055354:Rapamycin-Metformin_downregulated |
| | | WBPaper00055354:Rifampicin-Allantoin_downregulated |
| | | WBPaper00055482:pmt-2(RNAi)_upregulated |
| | | WBPaper00055971:nhl-2(ok818)_25C_upregulated |
| | | WBPaper00056034:pals-22(jy3)_upregulated |
| | | WBPaper00056167:Cry5B_downregulated |
| | | WBPaper00056275:P.aeruginosa_downregulated |
| | | WBPaper00056275:P.aeruginosa_downregulated_atf-7(qd22qd130)_dependent |
| | | WBPaper00056275:P.aeruginosa_downregulated_pmk-1(km25)_dependent |
| | | WBPaper00056443:sek-1(km4)_upregulated |
| | | WBPaper00056900:PID-3_interacting |
| | | WBPaper00057140:meg-3(tm4259)_meg-4(ax2026)_downregulated |
| | | WBPaper00057143:ztf-11(RNAi)_upregulated |
| | | WBPaper00057158:mdt-15(tm2182)_dependent_15C_downregulated |
| | | WBPaper00057288:Cold_downregulated_protein |
| | | WBPaper00057288:Cold_downregulated_transcript |
| | | WBPaper00058958:100mGy-irradiation-72h_upregulated |
| | | WBPaper00059191:hsp-16.2p-LIN-29_upregulated |
| | | WBPaper00059328:mrps-5(RNAi)_upregulated_protein |
| | | WBPaper00059356:BAZ-2_SET-6_interacting |
| | | WBPaper00059471:EGL-43_interacting |
| | | WBPaper00059537:ngn-1(ok2200)_upregulated |
| | | WBPaper00059763:neuron_expressed |
| | | WBPaper00059895:wounding_upregulated |
| | | WBPaper00059987:Wounding_upregulated |
| | | WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi) |
| | | WBPaper00060459:bcat-1(RNAi)_upregulated |
| | | WBPaper00060661:sensory-neuron_enriched |
| | | WBPaper00060683:hlh-11(ko1)_upregulated |
| | | WBPaper00060811:L1_vs_adult_downregulated_neural |
| | | WBPaper00060871:M.humicola-infection_12h_regulated |
| | | WBPaper00061274:hypergravity_15xg_upregulated |
| | | WBPaper00061340:ALA |
| | | WBPaper00061340:ALM_BDU |
| | | WBPaper00061340:Anterior_arcade_cell |
| | | WBPaper00061340:ant_arc_V |
| | | WBPaper00061340:AVA |
| | | WBPaper00061340:AVJ |
| | | WBPaper00061340:AVL |
| | | WBPaper00061340:M_cell |
| | | WBPaper00061340:Neuroblast_AIZ_FLP |
| | | WBPaper00061340:Pharyngeal_intestinal_valve |
| | | WBPaper00061340:pm1_pm2 |
| | | WBPaper00061340:Posterior_arcade_cell |
| | | WBPaper00061340:Rectal_gland |
| | | WBPaper00061340:RID |
| | | WBPaper00061340:RMED |
| | | WBPaper00061340:Z1_Z4 |
| | | WBPaper00061341:28C_24h_upregulated |
| | | WBPaper00061377:MYRF-2_interacting |
| | | WBPaper00061439:unc-30(ok613)_upregulated |
| | | WBPaper00061527:F54D5.3_7003-F54D5.3_7004 |
| | | WBPaper00061651:CEPsh_enriched |
| | | WBPaper00061651:Distal_tip_cell_enriched |
| | | WBPaper00061651:I1_enriched |
| | | WBPaper00061651:Spermatheca_enriched |
| | | WBPaper00062002:Day4-adult_secretome |
| | | WBPaper00062056:lin-37(n758)_downregulated |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062193:skn-1(RNAi)_upregulated |
| | | WBPaper00062325:etr-1(lq61)_upregulated |
| | | WBPaper00062354:H.zoospora_6h_regulated |
| | | WBPaper00062554:MAGU-2_interacting |
| | | WBPaper00062590:Aging_downregulated_hypodermis |
| | | WBPaper00062669:extracellular-vesicle_protein |
| | | WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA |
| | | WBPaper00064005:starvation_downregulated_N2_mRNA |
| | | WBPaper00064055:trl-1(cas1077)_downregulated_starved |
| | | WBPaper00064071:NHR-49_interacting |
| | | WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20) |
| | | WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141) |
| | | WBPaper00064201:SNA-3_interacting |
| | | WBPaper00064315:mes-4(bn73)_downregulated_PGCs |
| | | WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs |
| | | WBPaper00064727:daf-2(e1370)_upregulated |
| | | WBPaper00064735:bet-1(RNAi)_vs_N2_upregulated |
| | | WBPaper00064735:bet-1(uth41)_vs_N2_upregulated |
| | | WBPaper00065120:body-muscle-transcriptome |
| | | WBPaper00065258:anchor-cell_enriched |
| | | WBPaper00065373:Cisplatin_upregulated_WT |
| | | WBPaper00065373:sek-1(km4)_upregulated_cisplatin |
| | | WBPaper00065623:54 |
| | | WBPaper00065841:11_2 |
| | | WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein |
| | | WBPaper00065993:glp-1(e2141)_upregulated |
| | | cgc4386_cluster_1_1 |
| | | cgc4489_group_3 |
| | | WBPaper00005124:estrogen_10-5M_regulated |
| | | WBPaper00024393:strongly_regulated_dauer_genes |
| | | WBPaper00025032:cluster_55 |
| | | WBPaper00025032:cluster_124 |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Enriched_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00026929:sir-2.1_overexpression_regulated |
| | | WBPaper00029437:dcr-1_upregulated |
| | | WBPaper00030839:Embryo_A_Class |
| | | WBPaper00030839:Embryo_Pan_Neuronal |
| | | WBPaper00031003:0hr_muscle_depleted |
| | | WBPaper00031003:total_muscle_depleted |
| | | WBPaper00031252:AIN-1_IP_enriched |
| | | WBPaper00035227:heat_shock_regulated |
| | | WBPaper00035504:daf-2(e1370)_upregulated |
| | | WBPaper00036123:Atrazine_regulated |
| | | WBPaper00036286:Pattern_F |
| | | WBPaper00037695:CC_3-day |
| | | WBPaper00037695:LD_3-day |
| | | WBPaper00038231:Cry5B_1.5-fold_upregulated |
| | | WBPaper00038231:Cry5B_2-fold_upregulated |
| | | WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up |
| | | WBPaper00040210:Chlorpyrifos_24C_regulated |
| | | WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated |
| | | WBPaper00041002:HF_3d_0.2mM_Up |
| | | WBPaper00041606:CE_B.thuringiensis-DB27_regulated |
| | | WBPaper00041606:CE_X.nematophila_regulated |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_48h |
| | | WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_3h |
| | | WBPaper00042274:tbx-2(bx59)_upregulated |
| | | WBPaper00045960:L4-lethargus_upregulated |
| | | WBPaper00046548:dafachronic-acid_downregulated |
| | | WBPaper00047070:xpa-1_UV_upregulated |
| | | WBPaper00048624:hlh-25(ok1710)_upregulated |
| | | WBPaper00048637:lin-35(n745)_starvation_upregulated |
| | | WBPaper00048989:eat-2(ad465)_rapamycin_downregulated |
| | | WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO |
| | | WBPaper00048989:N2_rapamycin_upregulated |
| | | [cgc5767]:cluster_57 |
| | | [cgc5767]:expression_class_M |
| | | [cgc5767]:expression_class_MD |
| | | [cgc5767]:expression_class_MD_pd(41_min) |
| | | [cgc5767]:expression_class_SM |
| | | [cgc5767]:expression_class_SMD |
| | Interaction (36) |
| | WBProcess | WBbiopr:00000015 |
| Map_info | Map | III | Position | -1.97258 | Error | 0.014291 |
| | Positive | Positive_clone | ZC155 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Mapping_data | Multi_point | 4167 |
| | | | 4513 |
| | Pseudo_map_position |
| Reference (17) |
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene |
