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WormBase Tree Display for WBProcess: WBbiopr:00000015

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Name Class

WBbiopr:00000015Public_nameCorpse engulfment
SummaryCell corpses are removed through phagocytosis as a final step of apoptosis. The removal of these corpses protects the organism from harmful contents that may be released from the dying cell. Cell corpse removal requires properly identifying, ingesting and degrading the dying cell. During this process the engulfing cell undergoes cytoskeletal reorganization to send a projection towards the apoptotic cell. Over a dozen genes have been identified in C. elegans that play a role in apoptosis, with many of them, including ced-12, ced-10, ced-5, and ced-2, being required for this final cell corpse engulfment step.
Other_namePhagocytosis
Related_topicSpecialisation_ofWBbiopr:00000014
Involved_entityGene (29)
Interaction (60)
MoleculeWBMol:00003183Paper_evidenceWBPaper00005874
Associated_withPhenotypeWBPhenotype:0000241Paper_evidenceWBPaper00005874
GO_termGO:0043652
PathwayDB_infoDatabaseWikiPathwaysPathwayWP2226
WP2231
Reference (41)