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WormBase Tree Display for Gene: WBGene00001795

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Name Class

WBGene00001795EvidenceCGC_data_submission
SMapS_parentSequenceC05C12
IdentityVersion1
NameCGC_namegtl-1Person_evidenceWBPerson51
Sequence_nameC05C12.3
Molecular_nameC05C12.3
C05C12.3.1
CE33754
Other_nametag-33CGC_data_submission
CELE_C05C12.3Accession_evidenceNDBBX284604
Public_namegtl-1
DB_infoDatabaseAceViewgene4M14
WormQTLgeneWBGene00001795
WormFluxgeneWBGene00001795
NDBlocus_tagCELE_C05C12.3
PanthergeneCAEEL|WormBase=WBGene00001795|UniProtKB=G5ECM4
familyPTHR13800
NCBIgene178031
RefSeqproteinNM_069710.6
TrEMBLUniProtAccG5ECM4
UniProt_GCRPUniProtAccG5ECM4
OMIMgene603576
605692
608961
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgtl
Allele (118)
StrainWBStrain00003262
WBStrain00035612
RNASeq_FPKM (74)
GO_annotation00012064
00012065
00012066
00012067
00012068
00012069
Ortholog (46)
ParalogWBGene00001651Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00001796Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00000425Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00004149Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00008731Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00020972Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00021404Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00021408Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptiongtl-1 encodes a TRPM subfamily member of the TRP channel family that affects the periodicity of the defecation cycle in combination with gon-2; expression includes the intestine.Paper_evidenceWBPaper00005092
WBPaper00011328
Curator_confirmedWBPerson48
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable monoatomic cation channel activity. Involved in defecation. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis-parkinsonism/dementia complex 1; cataract; and congenital stationary night blindness 1C. Is an ortholog of human TRPM1 (transient receptor potential cation channel subfamily M member 1); TRPM3 (transient receptor potential cation channel subfamily M member 3); and TRPM7 (transient receptor potential cation channel subfamily M member 7).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110867Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7146)
DOID:0050534Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7146)
DOID:0111246Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:17994)
DOID:83Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:17992)
Molecular_infoCorresponding_CDSC05C12.3
Corresponding_CDS_historyC05C12.3:wp99
Corresponding_transcriptC05C12.3.1
Other_sequenceFK807706.1
MHC01321_1
MH01590
Dviv_isotig25122
FM207828.1
Associated_featureWBsf668304
WBsf1018190
WBsf230849
Experimental_infoRNAi_resultWBRNAi00010181Inferred_automaticallyRNAi_primary
WBRNAi00039701Inferred_automaticallyRNAi_primary
WBRNAi00001394Inferred_automaticallyRNAi_primary
WBRNAi00001519Inferred_automaticallyRNAi_primary
Expr_patternChronogram1622
Expr3713
Expr5160
Expr8230
Expr8232
Expr1017897
Expr1031057
Expr1143801
Expr2012342
Expr2030579
Drives_constructWBCnstr00003737
WBCnstr00007204
WBCnstr00007207
WBCnstr00007208
WBCnstr00007209
WBCnstr00011622
WBCnstr00013197
WBCnstr00021190
WBCnstr00036678
Construct_productWBCnstr00011622
WBCnstr00013197
WBCnstr00036678
Microarray_results (18)
Expression_clusterWBPaper00029359_1280
WBPaper00029359_1444
WBPaper00029359_1504
WBPaper00029359_1604
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00036375:enriched_in_PVD_OLL
WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:intestine_larva_enriched
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044578:reduced-humidity_downregulated_microarray
WBPaper00044736:oscillating_dev_expression
WBPaper00045521:Spermatogenic
WBPaper00045934:wrn-1(gk99)_upregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00047131:daf-2(e1370)_downregulated_N2-background
WBPaper00048923:Aging_regulated
WBPaper00048971:daf-16(mgDf50)_upregulated_L1
WBPaper00048988:neuron_expressed
WBPaper00049018:swsn-2.2(RNAi)_upregulated
WBPaper00049498:npr-1(ur89)_regulated_7
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
WBPaper00049732:blmp-1(tm548);daf-7(e1372ts)_vs_daf-7(e1372ts)_upregulated
WBPaper00049905:Age_variant_expression
WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:intestine_expressed
WBPaper00051039:intestine_enriched
WBPaper00051257:Levamisole_upregulated
WBPaper00051404:alg-2(ok304)_upregulated
WBPaper00051558:fog-2(q71)_regulated
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053302:alovudine_24h_regulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053302:zidovudine_24h_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053388:dauer_regulated_Cluster1
WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_doenregulated
WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
WBPaper00053810:daf-2(e1370)_downregulated
WBPaper00053814:15C_downregulated_PY79
WBPaper00055060:flr-1(RNAi)_upregulated
WBPaper00055354:Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Metformin_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055364:uaf-1(n4588)_downregulated
WBPaper00055971:nhl-2(ok818)_25C_downregulated
WBPaper00056034:pals-22(jy3)_upregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_upregulated_N2
WBPaper00056139:soil-microbiota_upregulated
WBPaper00056161:male_enriched_siRNA
WBPaper00056290:mdt-15(mg584)_downregulated
WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
WBPaper00056443:DietaryRestriction_upregulated
WBPaper00056443:sek-1(km4)_downregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056471:S.aureus-4h_upregulated_N2
WBPaper00056826:hmc_biased
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057006:DietaryRestriction_upregulated
WBPaper00057068:ints-4(RNAi)_downregulated
WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium
WBPaper00058598:mex-1(or286)_upregulated
WBPaper00058598:mex-3(eu149)_upregulated
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058598:spn-4(tm291)_upregulated
WBPaper00058711:paraquat_downregulated
WBPaper00058725:sftb-1(cer6)_downregulated
WBPaper00058948:PA14_downregulated
WBPaper00058969:RIS_depleted
WBPaper00059191:hsp-16.2p-LIN-29_downregulated
WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
WBPaper00059566:wdr-23(mac32)_upregulated
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059824:rnp-6(dh1127)_regulated_OP50
WBPaper00059895:wounding_upregulated
WBPaper00059987:Wounding_upregulated
WBPaper00060014:set-2(zr2012)_upregulated
WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060661:sensory-neuron_depleted
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
WBPaper00061007:HB101_upregulated
WBPaper00061007:S.aquatilis_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061274:hypergravity_15xg_downregulated
WBPaper00061274:microgravity_downregulated
WBPaper00061285:wounding_24h_upregulated
WBPaper00061340:AVJ
WBPaper00061340:Neuroblast_ALA_RMED
WBPaper00061340:OLQ_grandparent
WBPaper00061340:OLQ_parent
WBPaper00061340:RID
WBPaper00061340:RID_parent
WBPaper00061439:unc-30(ok613)_downregulated
WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
WBPaper00061479:ubc-9(ne4833)_upregulated
WBPaper00061527:gtl-1-hum-8_16432
WBPaper00061530:nhr-49(e2144)_upregulated
WBPaper00061753:csr-1(tor159)_upregulated_25C
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062193:hsf-1(RNAi)_downregulated
WBPaper00062193:skn-1(RNAi)_downregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062345:bortezomib_4h_downregulated_N2
WBPaper00064005:starvation_upregulated_aptf-1(gk794)_mRNA
WBPaper00064005:starvation_upregulated_N2_mRNA
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064156:lbp-3(overexpress)_upregulated
WBPaper00064156:lipl-4(overexpress)_upregulated
WBPaper00064306:Agaro-oligosaccharides_upregulated
WBPaper00064539:nhr-114(gk849)_upregulated
WBPaper00064716:paraquat_downregulated
WBPaper00064939:vit-5(RNAi)_upregulated
WBPaper00065086:JU1400_N.ausubeli_regulated
WBPaper00065086:JU1400_N.ferruginous_regulated
WBPaper00065086:N2_N.ausubeli_regulated
WBPaper00065225:nhr-42(tm1375)_upregulated_S.aureus-infected
WBPaper00065258:anchor-cell_depleted
WBPaper00065734:unc-25(e156)_upregulated
WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00066062:xrep-4(lax137)_upregulated
WBPaper00066232:ash-2(RNAi)_downregulated_WT
WBPaper00024393:strongly_regulated_dauer_genes
WBPaper00026929:Resveratrol_regulated_daf-16
WBPaper00031532:Larva_Pan_Neuronal_Depleted
WBPaper00032165:differentially_expressed_with_age_medoid_1
WBPaper00036286:Pattern_C
WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
WBPaper00037147:heatshock_downregulated
WBPaper00038172:crh-1null_up_regulated
WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2down
WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
WBPaper00040963:TA200_up
WBPaper00040963:TA300_up
WBPaper00041002:HF_3d_2.0mM_Up
WBPaper00041002:HQ_3d_2.0mM_Up
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041960:N2_fasting_upregulated_9hto12h
WBPaper00041960:N2_fasting_upregulated_anytime
WBPaper00045263:0.1mM-paraquat_downregulated
WBPaper00045263:nuo-6(qm200)_downregulated
WBPaper00045960:L4-lethargus_upregulated
WBPaper00047070:N2_starvation_upregulated
WBPaper00047070:N2_UV_upregulated
WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
WBPaper00053236:daf-16(mgDF50)_regulated_Starved
WBPaper00053236:Starvation_regulated_N2
WBPaper00055899:nitroguanidine_regulated
Interaction (18)
Map_infoMapIVPosition4.92955Error0.001473
PositivePositive_cloneC05C12Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4386
4526
Pseudo_map_position
Reference (29)
RemarkSequence connection from Kwan CSM, Ragnauth CD and Baylis HA [021008 ck1]
Gene name created from parsing 'genotype' field from CGC strain informationCGC_data_submission
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene