WormBase Tree Display for Gene: WBGene00001796

WBGene00001796 SMap: S_parent: Sequence: F54D1
  Identity: Version: 1
    Name: CGC_name: gtl-2 Person_evidence: WBPerson51
      Sequence_name: F54D1.5
      Molecular_name: F54D1.5
        F54D1.5.1
        CE40563
      Other_name: CELE_F54D1.5 Accession_evidence: NDB BX284604
      Public_name: gtl-2
    DB_info: Database: AceView gene 4M45
        WormQTL gene WBGene00001796
        WormFlux gene WBGene00001796
        NDB locus_tag CELE_F54D1.5
        Panther gene CAEEL|WormBase=WBGene00001796|UniProtKB=Q20766
          family PTHR13800
        NCBI gene 178036
        RefSeq protein NM_069717.7
        TrEMBL UniProtAcc Q20766
        UniProt_GCRP UniProtAcc Q20766
        OMIM gene 603576
            605692
            608961
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gtl
    Allele (94)
    Strain: WBStrain00024196
      WBStrain00005419
      WBStrain00049842
      WBStrain00049843
    RNASeq_FPKM (74)
    GO_annotation: 00069079
      00069080
      00069081
      00069082
      00069083
      00109391
      00109392
      00109393
      00109394
    Ortholog (48)
    Paralog: WBGene00001651 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00001795 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00000425 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00004149 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00008731 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00020972 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00021404 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00021408 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: gtl-2 encodes a predicted receptor-activated calcium channel and represents a family of calcium channels, the other two family members being gtl-1 and gon-2. Paper_evidence: WBPaper00011683
            WBPaper00023556
          Curator_confirmed: WBPerson324
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable monoatomic cation channel activity. Predicted to be involved in monoatomic cation transmembrane transport. Located in basal plasma membrane. Expressed in excretory canal; excretory cell; hypodermis; pharyngeal muscle cell; and pharynx. Used to study MASA syndrome. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis-parkinsonism/dementia complex 1; cataract; and congenital stationary night blindness 1C. Is an ortholog of human TRPM1 (transient receptor potential cation channel subfamily M member 1); TRPM3 (transient receptor potential cation channel subfamily M member 3); and TRPM7 (transient receptor potential cation channel subfamily M member 7). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Experimental_model: DOID:0060246
    Potential_model: DOID:0110867 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7146)
      DOID:0050534 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7146)
      DOID:0111246 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:17994)
      DOID:83 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:17992)
  Models_disease_asserted: WBDOannot00000053
  Molecular_info: Corresponding_CDS: F54D1.5
    Corresponding_CDS_history: F54D1.5:wp57
      F54D1.5:wp167
    Corresponding_transcript: F54D1.5.1
    Other_sequence (12)
    Associated_feature: WBsf718194
      WBsf997800
      WBsf997801
      WBsf1018191
      WBsf021262
      WBsf229125
  Experimental_info: RNAi_result: WBRNAi00109632 Inferred_automatically: RNAi_primary
      WBRNAi00015597 Inferred_automatically: RNAi_primary
      WBRNAi00109535 Inferred_automatically: RNAi_primary
      WBRNAi00109341 Inferred_automatically: RNAi_primary
      WBRNAi00048282 Inferred_automatically: RNAi_primary
      WBRNAi00109244 Inferred_automatically: RNAi_primary
      WBRNAi00109438 Inferred_automatically: RNAi_primary
      WBRNAi00001304 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr3714
      Expr8231
      Expr9011
      Expr9299
      Expr1027597
      Expr1152084
      Expr2012343
      Expr2030580
    Drives_construct: WBCnstr00007205
      WBCnstr00011623
      WBCnstr00013198
      WBCnstr00013672
      WBCnstr00013883
      WBCnstr00036677
      WBCnstr00042689
    Construct_product: WBCnstr00011623
      WBCnstr00013198
      WBCnstr00013672
      WBCnstr00013883
      WBCnstr00036677
      WBCnstr00042689
      WBCnstr00042690
    Microarray_results (19)
    Expression_cluster (120)
    Interaction (21)
  Map_info: Map: IV Position: 4.94064 Error: 0.001769
    Positive: Positive_clone: F54D1 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4386
    Pseudo_map_position
  Reference (24)
  Remark: Sequence connection from Kwan CSM, Ragnauth CD and Baylis HA [021008 ck1]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene