gtl-2 encodes a predicted receptor-activated calcium channel and represents a family of calcium channels, the other two family members being gtl-1 and gon-2.
Predicted to enable monoatomic cation channel activity. Predicted to be involved in monoatomic cation transmembrane transport. Located in basal plasma membrane. Expressed in excretory canal; excretory cell; hypodermis; pharyngeal muscle cell; and pharynx. Used to study MASA syndrome. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis-parkinsonism/dementia complex 1; cataract; and congenital stationary night blindness 1C. Is an ortholog of human TRPM1 (transient receptor potential cation channel subfamily M member 1); TRPM3 (transient receptor potential cation channel subfamily M member 3); and TRPM7 (transient receptor potential cation channel subfamily M member 7).
Sequence connection from Kwan CSM, Ragnauth CD and Baylis HA [021008 ck1]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.