WormBase Tree Display for Gene: WBGene00012591

WBGene00012591 SMap: S_parent: Sequence: Y38E10A
  Identity: Version: 2
    Name (5)
    DB_info: Database: AceView gene 2M910
        WormQTL gene WBGene00012591
        WormFlux gene WBGene00012591
        NDB locus_tag CELE_Y38E10A.13
        Panther gene CAEEL|WormBase=WBGene00012591|UniProtKB=Q9NAJ8
          family PTHR34602
        NCBI gene 189660
        RefSeq protein NM_064295.6
        TREEFAM TREEFAM_ID TF319947
        TrEMBL UniProtAcc Q9NAJ8
        UniProt_GCRP UniProtAcc Q9NAJ8
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:54 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 19 Nov 2008 14:26:07 WBPerson2970 Name_change: CGC_name: nspe-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: nspe
    Allele (14)
    RNASeq_FPKM (74)
    Ortholog (62)
    Paralog: WBGene00012587 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00012589 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00012590 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00012594 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00012593 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00175028 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00012604 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00012603 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
    Structured_description: Automated_description: Enriched in AINL; AINR; PLM; and hypodermis based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirty-five chemicals including methylmercury hydroxide; 1-methylnicotinamide; and rotenone based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1412) and Protein of unknown function DUF1412. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y38E10A.13
    Corresponding_transcript: Y38E10A.13.1
    Associated_feature: WBsf650663
      WBsf224086
  Experimental_info: RNAi_result: WBRNAi00036839 Inferred_automatically: RNAi_primary
      WBRNAi00020283 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1159531
      Expr2014487
      Expr2032726
    Drives_construct: WBCnstr00029895
    Construct_product: WBCnstr00029895
    Microarray_results (14)
    Expression_cluster: WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_downregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040560:hpl-2_L3_downregulated
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00043945:MeHg_upregulated
      WBPaper00044037:eat-2_upregulated
      WBPaper00044260:1-methylnicotinamide_downregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044578:reduced-humidity_upregulated_microarray
      WBPaper00044736:flat_dev_expression
      WBPaper00044857:BAR-1_downregulated
      WBPaper00045420:fertilization_upregulated_transcript
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045774:clk-1_upregulated
      WBPaper00045934:wrn-1(gk99)_upregulated
      WBPaper00046012:tdp-1(ok803)_downregulated
      WBPaper00046741:Garlic-Extract_upregulated_mRNA
      WBPaper00046887:WNT-target
      WBPaper00048611:MnCl2_downregulated
      WBPaper00049377:MWCNT_upregulated
      WBPaper00049498:npr-1(ur89)_regulated_7
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049635:dop-1(vs100)_upregulated
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:mir-34(OverExpression)_vs_N2_regulated_adult_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_adult_25C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050504:hrp-2(RNAi)_upregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051257:Levamisole_downregulated
      WBPaper00051388:Glucose-diet_downregulated
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00051404:alg-2(ok304)_upregulated
      WBPaper00053020:OrsayVirus-infection_upregulated
      WBPaper00053020:sid-3(ok973)_upregulated
      WBPaper00053020:sta-1(ok587)_upregulated
      WBPaper00053092:procyanidins_upregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053295:lin-22(icb38)_upregulated
      WBPaper00053295:lin-22(ot267)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:alovudine_72h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053664:ins-11(tm1053)_upregulated
      WBPaper00053737:Anatase-TiO2-Nanoparticles_downregulated
      WBPaper00053771:up_at_3h-NaCl
      WBPaper00053771:up_at_24h-NaCl
      WBPaper00053771:up_at_dpy-7(e88)
      WBPaper00053888:drh-3(rrr2)_downregulated
      WBPaper00053909:N2_vs_CB4856_upregulated
      WBPaper00054191:H3.3(null)_embryo_upregulated
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00054872:egl-9(sa307)_upregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055354:Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055827:daf-2(e1370)_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055897:heat-shock_upregulated
      WBPaper00055971:nhl-2(ok818)_20C_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056039:efa-6(tm3124)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056290:mdt-15(mg584)_upregulated
      WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1
      WBPaper00056586:kri-1(ok1251)_upregulated
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057154:HeatShock_upregulated_mRNA
      WBPaper00057158:mdt-15(tm2182)_dependent_15C_upregulated
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058948:PA14_upregulated
      WBPaper00058955:heatshock_upregulated_CE
      WBPaper00059117:B.subtilis_downregulated
      WBPaper00059253:stearic-acid_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059378:cec-4(ok3124);lmn-1(Y59C)_vs_lmn-1(Y59C)_downregulated
      WBPaper00059566:wdr-23(mac32)_upregulated
      WBPaper00059605:mut-16(pk710)_upregulated
      WBPaper00059739:hira-1(gk835598)_upregulated_L4
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059987:Wounding_upregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060084:cco-1(RNAi)_upregulated_lin-40(yth27)
      WBPaper00060084:cco-1(RNAi)_upregulated_N2
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061040:eat-2(ad1116)_upregulated
      WBPaper00061340:AIN
      WBPaper00061340:Hypodermis
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061527:T24C12.3-C01G10.9
      WBPaper00061753:csr-1(tor159)_downregulated_20C
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00061995:mter-4(syb3662syb3403)_downregulated
      WBPaper00062056:dpl-1(n2994)_upregulated
      WBPaper00062056:lin-15B(n744)_upregulated
      WBPaper00062056:lin-15B(we23)_upregulated
      WBPaper00062056:lin-35(n745)_upregulated
      WBPaper00062056:lin-36(n766)_upregulated
      WBPaper00062056:lin-37(n758)_upregulated
      WBPaper00062056:met-2(n4256)_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:daf-16(RNAi)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062672:let-418(n3536)_upregulated
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064494:postdauer_downregulated_WholeAnimal
      WBPaper00064505:tamoxifen_downregulated
      WBPaper00064532:pals-22(jy3)_downregulated
      WBPaper00064532:pals-25(icb98)_upregulated
      WBPaper00064637:cox-5B(RNAi)_upregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00064721:fasn-1(g14)_downregulated_starved
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065096:npr-8(ok1439)_upregulated_Day1_25C
      WBPaper00065149:lin-52(n771)_downregulated
      WBPaper00065158:AFD_depleted
      WBPaper00065288:mdt-15(tm2182)_downregulated
      WBPaper00065392:Lb.reuteri_upregulated
      WBPaper00065392:Lb.rhamnosus_upregulated
      WBPaper00065392:P.pentosaceus_upregulated
      WBPaper00065560:E.coli-HB101_downregulated_F3
      WBPaper00065734:unc-25(e156)_upregulated
      WBPaper00065746:eat-2(ad1113)_upregulated
      WBPaper00065746:tmc-1(rg1003)_upregulated
      WBPaper00065749:Heat-Shock_upregulated_endu-2(tm4977)
      WBPaper00065749:Heat-Shock_upregulated_N2
      WBPaper00065835:mtH2S-AP39-L1-treatment_upregulated_Day1
      WBPaper00065841:2_0
      WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00065995:M.humicola-extract_upregulated_N2
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      WBPaper00066232:hsf-1(RNAi)_downregulated_WT
      cgc4489_group_12
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_depleted
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00031832:slr-2_regulated
      WBPaper00032948:StarveUp1
      WBPaper00034661:AgNPs_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-7_regulated
      WBPaper00035873:osmotically_regulated
      WBPaper00036375:depleted_in_PVD_OLL
      WBPaper00038172:aak-2overexpression_up_regulated
      WBPaper00038172:crh-1null_up_regulated
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00038231:Cry5B_2-fold_downregulated
      WBPaper00039866:ClassComp_daf-19_downregulated
      WBPaper00039866:SAM_daf-19_downregulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040876:mir-35_downregulated
      WBPaper00040963:Q200_down
      WBPaper00041002:HQ_3d_2.0mM_Down
      WBPaper00041211:RPW-24_Up
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_24h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00042067:Cu2+_upregulated_WT
      WBPaper00042128:gei-8(ok1671)_upregulated
      WBPaper00042178:hlh-29(tm284)_upregulated
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00042574:JU1580_OrsayVirus_upregulated
      WBPaper00042574:rde-1(ne219)_OrsayVirus_upregulated
      WBPaper00043980:arsenic_upregulated
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00045865:biofilm_downregulated_B
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00048637:lin-35(n745)_starvation_upregulated
      WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO
      WBPaper00048989:N2_allantoin_downregulated
      WBPaper00049311:AgNO3_regulated
      WBPaper00050767:Octopamine_induced
      WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo
      WBPaper00055899:nitroguanidine_regulated
      WBPaper00055899:nitrotriazolone_regulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
      WBPaper00057098:SiO2-nanoparticles_downregulated
    Interaction: WBInteraction000549461
      WBInteraction000549462
  Map_info: Map: II Position: 10.5075
    Positive: Positive_clone: Y38E10A Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene