| WBGene00012005 | SMap | S_parent | Sequence | CHROMOSOME_II |
|---|
| Identity | Version | 4 |
| | Name | CGC_name | jun-1 | Person_evidence | WBPerson2962 |
| | | | | | WBPerson443 |
| | | Sequence_name | T24H10.7 |
| | | Molecular_name (27) |
| | | Other_name | CELE_T24H10.7 | Accession_evidence | NDB | BX284602 |
| | | Public_name | jun-1 |
| | DB_info | Database | AceView | gene | 2J421 |
| | | | WormQTL | gene | WBGene00012005 |
| | | | WormFlux | gene | WBGene00012005 |
| | | | NDB | locus_tag | CELE_T24H10.7 |
| | | | Panther | gene | CAEEL|WormBase=WBGene00012005|UniProtKB=G5ECU7 |
| | | | | family | PTHR11462 |
| | | | NCBI | gene | 174452 |
| | | | RefSeq | protein | NM_001356878.3 |
| | | | | | NM_001356880.3 |
| | | | | | NM_001136355.4 |
| | | | | | NM_001356881.3 |
| | | | | | NM_001383910.2 |
| | | | | | NM_001356879.3 |
| | | | | | NM_001027195.4 |
| | | | | | NM_001027197.5 |
| | | | | | NM_001027196.5 |
| | | | SwissProt | UniProtAcc | G5ECU7 |
| | | | TrEMBL | UniProtAcc | A0A2C9C3K0 |
| | | | | | A0A2C9C3E7 |
| | | | | | A0A2C9C2T0 |
| | | | | | A0A2C9C2Y8 |
| | | | UniProt_GCRP | UniProtAcc | G5ECU7 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 26 May 2004 16:54:53 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 |
| | | | 2 | 29 Nov 2004 12:57:28 | WBPerson1983 | Event | Acquires_merge | WBGene00012001 |
| | | | 3 | 27 Apr 2007 10:10:56 | WBPerson1983 | Event | Acquires_merge | WBGene00012006 |
| | | | 4 | 07 Nov 2007 09:36:21 | WBPerson2970 | Name_change | CGC_name | jun-1 |
| | | Acquires_merge | WBGene00012001 |
| | | | WBGene00012006 |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | jun |
| | Allele (304) |
| | Strain (2) |
| | RNASeq_FPKM (74) |
| | GO_annotation (28) |
| | Contained_in_operon | CEOP2709 |
| | Ortholog (31) |
| | Structured_description | Concise_description | jun-1 encodes a basic-leucine zipper (bZIP) transcription factor that is the C. elegans JUN homolog; jun-1 activity is essential for regulation of ovulation, and thus normal levels of fertility; in regulating ovulation, JUN-1 functions with FOS-1 to regulate expression of plc-1 which encodes a phospholipase C essential for IP3 production and ovulation; in addition, JUN-1 interacts with FOS-1 in vitro to form heterodimers capable of binding upstream regulatory sequences of egl-13, which encodes a transcription factor required for uterine cell fate specification; jun-1 is expressed in the uterus and the spermatheca. | Paper_evidence | WBPaper00031111 |
| | | | | | WBPaper00034689 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | Date_last_updated | 19 Jan 2010 00:00:00 |
| | | Automated_description | Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; positive regulation of RNA splicing; and response to starvation. Located in nucleus. Expressed in several structures, including excretory cell; hermaphrodite gonad; nervous system; pharyngeal-intestinal valve; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and lymphoma (multiple). Is an ortholog of human JUN (Jun proto-oncogene, AP-1 transcription factor subunit); JUNB (JunB proto-oncogene, AP-1 transcription factor subunit); and JUND (JunD proto-oncogene, AP-1 transcription factor subunit). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Disease_info | Potential_model (22) |
| Molecular_info | Corresponding_CDS | T24H10.7a |
| | | T24H10.7b |
| | | T24H10.7c |
| | | T24H10.7d |
| | | T24H10.7e |
| | | T24H10.7f |
| | | T24H10.7g |
| | | T24H10.7h |
| | | T24H10.7i |
| | Corresponding_CDS_history | T24H10.7:wp136 |
| | Corresponding_transcript | T24H10.7a.1 |
| | | T24H10.7b.1 |
| | | T24H10.7c.1 |
| | | T24H10.7d.1 |
| | | T24H10.7e.1 |
| | | T24H10.7f.1 |
| | | T24H10.7g.1 |
| | | T24H10.7h.1 |
| | | T24H10.7i.1 |
| | Other_sequence (42) |
| | Associated_feature (34) |
| | Gene_product_binds (375) |
| | Transcription_factor | WBTranscriptionFactor000109 |
| | | WBTranscriptionFactor000501 |
| Experimental_info | RNAi_result (33) |
| | Expr_pattern (14) |
| | Drives_construct | WBCnstr00012826 |
| | | WBCnstr00014260 |
| | | WBCnstr00014283 |
| | | WBCnstr00014284 |
| | | WBCnstr00014288 |
| | | WBCnstr00014300 |
| | | WBCnstr00014302 |
| | | WBCnstr00030207 |
| | Construct_product | WBCnstr00030207 |
| | Microarray_results (48) |
| | Expression_cluster | WBPaper00032031:DConiospora_downregulated_OligoArray_24h |
| | | WBPaper00033065:cyc-1(RNAi)_upregulated |
| | | WBPaper00037055:DAF-16_binding_DNA |
| | | WBPaper00037950:A-class-motor-neurons_L2-larva_expressed |
| | | WBPaper00037950:all-neurons_L2-larva_expressed |
| | | WBPaper00037950:BAG-neuron_blastula-embryo_expressed |
| | | WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed |
| | | WBPaper00037950:coelomocytes_L2-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed |
| | | WBPaper00037950:excretory-cell_L2-larva_expressed |
| | | WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed |
| | | WBPaper00037950:germline-precursors_blastula-embryo_expressed |
| | | WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed |
| | | WBPaper00037950:hypodermis_L3-L4-larva_expressed |
| | | WBPaper00037950:intestine_L2-larva_expressed |
| | | WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed |
| | | WBPaper00038061:aldicarb_downregulated |
| | | WBPaper00038168:lin-15B(n744)_upregulated |
| | | WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray |
| | | WBPaper00038438:Harposporium_24hr_upregulated_RNAseq |
| | | WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq |
| | | WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray |
| | | WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray |
| | | WBPaper00040221:DAF-12_target_ALF4 |
| | | WBPaper00042215:wdr-23(tm1817)_upregulated |
| | | WBPaper00042561:smg-2(RNAi)_upregulated |
| | | WBPaper00042561:smgl-1(RNAi)_upregulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated |
| | | WBPaper00045420:fertilization_downregulated_transcript |
| | | WBPaper00045521:Gender_Neutral |
| | | WBPaper00046121:ecdoderm_unique |
| | | WBPaper00046337:polysomal_N2_vs_daf-2_downregulated |
| | | WBPaper00046496:Rifampicin_upregulated |
| | | WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h |
| | | WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h |
| | | WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h |
| | | WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h |
| | | WBPaper00047132:glp-1(ts)-25C_upregulated |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049545:jmjd-3.1(+)_upregulated |
| | | WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated |
| | | WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr) |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_20C |
| | | WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_25C |
| | | WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult |
| | | WBPaper00050903:mir-35-41(nDf50)_25C_upregulated |
| | | WBPaper00050990:arcade_intestinal-valve_expressed |
| | | WBPaper00050990:body-muscle_expressed |
| | | WBPaper00050990:GABAergic-neuron_expressed |
| | | WBPaper00050990:hypodermis_expressed |
| | | WBPaper00050990:intestine_expressed |
| | | WBPaper00050990:NMDA-neuron_expressed |
| | | WBPaper00050990:pharynx_expressed |
| | | WBPaper00051404:alg-5(ram2)_downregulated |
| | | WBPaper00051558:aging_regulated |
| | | WBPaper00053184:sma-2(rax5)_upregulated |
| | | WBPaper00053184:sma-4(rax3)_upregulated |
| | | WBPaper00053295:lin-22(ot269)_upregulated |
| | | WBPaper00053302:zidovudine_72h_regulated |
| | | WBPaper00053388:dauer_regulated_Cluster4 |
| | | WBPaper00053771:up_at_3h-NaCl |
| | | WBPaper00053810:nuo-6(qm200)_upregulated |
| | | WBPaper00055049:S.gordonii_upregulated |
| | | WBPaper00055334:DLC-1_interacting |
| | | WBPaper00055354:eat-2(ad1116)_downregulated |
| | | WBPaper00055354:Rapamycin-Allantoin_downregulated |
| | | WBPaper00055354:Rapamycin-Metformin_downregulated |
| | | WBPaper00055565:AVK_enriched |
| | | WBPaper00056034:pals-22(jy3)_upregulated |
| | | WBPaper00056161:male_enriched_siRNA |
| | | WBPaper00056167:Cry5B_downregulated |
| | | WBPaper00056284:ints-5(RNAi)_upregulated |
| | | WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated |
| | | WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C |
| | | WBPaper00057154:HeatShock_downregulated_miRNA-target |
| | | WBPaper00057154:HeatShock_upregulated_mRNA |
| | | WBPaper00058598:mex-1(or286)_upregulated |
| | | WBPaper00058598:mex-3(eu149)_upregulated |
| | | WBPaper00058598:spn-4(tm291)_upregulated |
| | | WBPaper00058691:sin-3(tm1276)_downregulated |
| | | WBPaper00058725:sftb-1(cer6)_upregulated |
| | | WBPaper00058725:sftb-1(cer39)_downregulated |
| | | WBPaper00058948:PA14_downregulated |
| | | WBPaper00059027:neuron-synapses_depleted |
| | | WBPaper00059356:BAZ-2_SET-6_interacting |
| | | WBPaper00059471:EGL-43_interacting |
| | | WBPaper00059537:ngn-1(ok2200)_upregulated |
| | | WBPaper00059566:wdr-23(mac32)_upregulated |
| | | WBPaper00059598:HeatShock_upregulated |
| | | WBPaper00059664:srbc-48(ac23)_upregulated |
| | | WBPaper00059895:wounding_upregulated |
| | | WBPaper00059987:Wounding_upregulated |
| | | WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi) |
| | | WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi) |
| | | WBPaper00060358:B.thuringiensis_pathogen_regulated_N2 |
| | | WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr |
| | | WBPaper00060459:bcat-1(RNAi)_upregulated |
| | | WBPaper00060661:sensory-neuron_enriched |
| | | WBPaper00060683:hlh-11(ko1)_upregulated |
| | | WBPaper00060811:L1_vs_adult_upregulated_neural |
| | | WBPaper00061007:HB101_upregulated |
| | | WBPaper00061007:S.aquatilis_upregulated |
| | | WBPaper00061007:X.citri_upregulated |
| | | WBPaper00061203:let-418(n3536)_downregulated |
| | | WBPaper00061340:AVD |
| | | WBPaper00061340:ILso |
| | | WBPaper00061340:Parent_of_PVP_and_rect_V |
| | | WBPaper00061340:Pharyngeal_intestinal_valve |
| | | WBPaper00061341:28C_24h_upregulated |
| | | WBPaper00061479:hda-1(ne4752)_upregulated |
| | | WBPaper00061527:snt-4_17845-T27C4.1 |
| | | WBPaper00061651:AVJ_enriched |
| | | WBPaper00061651:RIG_enriched |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062354:H.zoospora_6h_regulated |
| | | WBPaper00062354:H.zoospora_12h_regulated |
| | | WBPaper00062446:nhr-8(hd117)_upregulated |
| | | WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064315:mes-4(bn73)_upregulated_EGCs |
| | | WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs |
| | | WBPaper00064716:paraquat_downregulated |
| | | WBPaper00064762:freezing-thaw_regulated |
| | | WBPaper00065086:JU1400_N.ausubeli_regulated |
| | | WBPaper00065086:JU1400_N.ferruginous_regulated |
| | | WBPaper00065086:N2_N.ausubeli_regulated |
| | | WBPaper00065120:body-muscle-transcriptome |
| | | WBPaper00065749:Heat-Shock-With-Recovery_upregulated_N2 |
| | | WBPaper00066110:tetraploid_vs_diploid_upregulated |
| | | WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2 |
| | | cgc4489_group_20 |
| | | cgc4489_male_enriched_transcription_factors |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00026980:intestine_enriched |
| | | WBPaper00029437:dcr-1_upregulated |
| | | WBPaper00030985:Photorhabdus_luminescens_downregulated |
| | | WBPaper00031003:0hr_muscle_depleted |
| | | WBPaper00031003:24hr_muscle_depleted |
| | | WBPaper00031003:total_muscle_depleted |
| | | WBPaper00031252:AIN-2_IP_enriched |
| | | WBPaper00031832:slr-2_regulated |
| | | WBPaper00034757:up_by_oxidative_stress |
| | | WBPaper00035084:L4_enriched_AIN-2_IP |
| | | WBPaper00035227:heat_shock_regulated |
| | | WBPaper00035588:alg-1(-)_upregulated |
| | | WBPaper00036130:mir-243_up_regulated |
| | | WBPaper00036286:Pattern_I |
| | | WBPaper00037695:LD_3-day |
| | | WBPaper00038060:SUMO-1_downregulated |
| | | WBPaper00038231:Cry5B_1.5-fold_upregulated |
| | | WBPaper00040210:Chlorpyrifos_16C_regulated |
| | | WBPaper00040210:Chlorpyrifos_24C_regulated |
| | | WBPaper00040858:eQTL_regulated_old |
| | | WBPaper00040985:AIN-2_asynchronous_muscle |
| | | WBPaper00041002:HF_3d_0.2mM_Up |
| | | WBPaper00041002:HQ_3d_0.2mM_Up |
| | | WBPaper00041002:HQ_3d_2.0mM_Up |
| | | WBPaper00041370:spg-7(RNAi)_upregulated |
| | | WBPaper00041606:CE_S.marcescens_regulated |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_48h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_51h |
| | | WBPaper00042274:tbx-2(bx59)_upregulated |
| | | WBPaper00044091:Bpseudomallei_induced_8h |
| | | WBPaper00044091:Bpseudomallei_induced_12h |
| | | WBPaper00045673:colistin_upregulated |
| | | WBPaper00045960:L1-L4-lethargus_upregulated |
| | | WBPaper00045960:L4-lethargus_upregulated |
| | | WBPaper00047070:N2_starvation_upregulated |
| | | WBPaper00047070:xpa-1_UV_upregulated |
| | | WBPaper00048637:lin-35(n745)_starvation_upregulated |
| | | WBPaper00048989:eat-2(ad465)_rapamycin_downregulated |
| | | WBPaper00048989:N2_rapamycin_upregulated |
| | | WBPaper00050515:nipi-3(fr4)_upregulated |
| | | WBPaper00055899:nitroguanidine_regulated |
| | | WBPaper00056330:mrps-5(RNAi)_upregulated |
| | | [cgc5767]:expression_class_M |
| | | [cgc5767]:expression_class_SM |
| | | [cgc6390]:Cluster_B |
| | Interaction (46) |
| Map_info | Map | II | Position | 1.04759 | Error | 0.001496 |
| | Positive | Positive_clone | T24H10 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Pseudo_map_position |
| Reference (24) |
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene |
