WormBase Tree Display for Gene: WBGene00004924

WBGene00004924 Evidence: Person_evidence: WBPerson298
  SMap: S_parent: Sequence: T23H2
  Identity: Version: 1
    Name: CGC_name: snt-4 Person_evidence: WBPerson508
      Sequence_name: T23H2.2
      Molecular_name: T23H2.2
        T23H2.2.1
        CE30456
      Other_name: CELE_T23H2.2 Accession_evidence: NDB BX284601
      Public_name: snt-4
    DB_info: Database: AceView gene 1H17
        WormQTL gene WBGene00004924
        WormFlux gene WBGene00004924
        NDB locus_tag CELE_T23H2.2
        Panther gene CAEEL|WormBase=WBGene00004924|UniProtKB=P91493
          family PTHR10024
        NCBI gene 172346
        RefSeq protein NM_059452.9
        TrEMBL UniProtAcc P91493
        UniProt_GCRP UniProtAcc P91493
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:36 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: snt
    Allele (63)
    Strain: WBStrain00031457
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog (41)
    Paralog: WBGene00004921 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00004922 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00004923 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00011682 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00004926 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00004925 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00004316 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00006306 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00020861 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable several functions, including SNARE binding activity; calcium ion binding activity; and phospholipid binding activity. Predicted to be involved in cellular response to calcium ion; regulation of secretion by cell; and vesicle-mediated transport. Predicted to be located in several cellular components, including axon; exocytic vesicle; and synapse. Expressed in intestine. Is an ortholog of human SYT4 (synaptotagmin 4). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: T23H2.2
    Corresponding_transcript: T23H2.2.1
    Other_sequence (34)
    Associated_feature: WBsf643368
      WBsf656408
      WBsf656409
      WBsf983938
      WBsf983939
      WBsf1009957
      WBsf217823
  Experimental_info: RNAi_result: WBRNAi00004292 Inferred_automatically: RNAi_primary
      WBRNAi00112397 Inferred_automatically: RNAi_primary
      WBRNAi00094904 Inferred_automatically: RNAi_primary
      WBRNAi00035895 Inferred_automatically: RNAi_primary
      WBRNAi00001274 Inferred_automatically: RNAi_primary
      WBRNAi00053987 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram493
      Expr4298
      Expr6755
      Expr1017961
      Expr1032453
      Expr1157532
      Expr2015979
      Expr2034214
    Drives_construct: WBCnstr00002585
      WBCnstr00011895
      WBCnstr00035319
    Construct_product: WBCnstr00035319
    Microarray_results (20)
    Expression_cluster: WBPaper00024970:GABAergic_neuron_specific
      WBPaper00029359_1166
      WBPaper00029359_1194
      WBPaper00029359_1197
      WBPaper00029359_1240
      WBPaper00029359_1243
      WBPaper00029359_1291
      WBPaper00029359_1336
      WBPaper00029359_1546
      WBPaper00029359_1549
      WBPaper00029359_1557
      WBPaper00029359_1599
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037682:sma-2_sma-4_upregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:A-class-motor-neurons_larva_enriched
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_larva_enriched
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:BAG-neuron_embryo_enriched
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_larva_enriched
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_larva_enriched
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00040990:PA14_upregulated
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044037:eat-2_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044656:tatn-1(qd182)_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044743:wdr-23_neuron_upregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_upregulated
      WBPaper00045974:NSM_enriched_DSN-treated_RNAseq
      WBPaper00045974:NSM_enriched_totalRNA_RNAseq
      WBPaper00046691:P1_enriched
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049001:EVN_enriched
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050015:ifg-1(RNAi)_upregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00054758:alg-1(gk204)_upregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055482:pmt-2(RNAi)_upregulated
      WBPaper00055565:AVK_enriched
      WBPaper00055648:male-tail_expressed
      WBPaper00055648:nerve-ring_expressed
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00057068:numr-1(RNAi)_downregulated
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058948:npr-8(ok1439)_downregulated_OP50
      WBPaper00058948:PA14_downregulated
      WBPaper00058969:RIS_enriched
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059566:wdr-23(mac32)_upregulated
      WBPaper00059605:mut-16(pk710)_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059763:neuron_expressed
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00060871:M.humicola-infection_48h_regulated
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061274:microgravity_downregulated
      WBPaper00061340:AFD
      WBPaper00061340:AIA
      WBPaper00061340:AIB
      WBPaper00061340:AIZ
      WBPaper00061340:ASI
      WBPaper00061340:AUA
      WBPaper00061340:AVA
      WBPaper00061340:AVD
      WBPaper00061340:AVH
      WBPaper00061340:AWA
      WBPaper00061340:AWC
      WBPaper00061340:BAG
      WBPaper00061340:DA_DB
      WBPaper00061340:DVA
      WBPaper00061340:FLP
      WBPaper00061340:I5
      WBPaper00061340:MC
      WBPaper00061340:RIB
      WBPaper00061340:RID
      WBPaper00061340:SMB
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061527:snt-4_17845-T27C4.1
      WBPaper00061527:sol-1-jnk-1_18695
      WBPaper00061651:ADA_enriched
      WBPaper00061651:ADF_enriched
      WBPaper00061651:AIA_enriched
      WBPaper00061651:AIB_enriched
      WBPaper00061651:AIN_enriched
      WBPaper00061651:AIY_enriched
      WBPaper00061651:AIZ_enriched
      WBPaper00061651:AQR_enriched
      WBPaper00061651:ASEL_enriched
      WBPaper00061651:ASI_enriched
      WBPaper00061651:AUA_enriched
      WBPaper00061651:AVA_enriched
      WBPaper00061651:AVJ_enriched
      WBPaper00061651:AWB_enriched
      WBPaper00061651:AWC_OFF_enriched
      WBPaper00061651:AWC_ON_enriched
      WBPaper00061651:BAG_enriched
      WBPaper00061651:BDU_enriched
      WBPaper00061651:DVB_enriched
      WBPaper00061651:I6_enriched
      WBPaper00061651:PHC_enriched
      WBPaper00061651:RIB_enriched
      WBPaper00061651:RIC_enriched
      WBPaper00061651:RID_enriched
      WBPaper00061651:RIF_enriched
      WBPaper00061651:RIH_enriched
      WBPaper00061651:RIM_enriched
      WBPaper00061651:RIV_enriched
      WBPaper00061651:RMD_LR_enriched
      WBPaper00061651:SIA_enriched
      WBPaper00061995:mter-4(syb3662syb3403)_downregulated
      WBPaper00062103:neuron_enriched
      WBPaper00062156:jmjd-5(zr1234)_downregulated_germline
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062520:qui-1(db104)_upregulated
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064156:lbp-3(overexpress)_upregulated
      WBPaper00064156:lipl-4(overexpress)_upregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064721:fasn-1(g14)_downregulated_starved
      WBPaper00064871:hypoxia_downregulated_F2
      WBPaper00064992:Eugenol_downregulated
      WBPaper00064992:heat-shock_upregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:25C_vs_15C_upregulated_AFD
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
      WBPaper00065749:Heat-Shock_downregulated_N2
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065841:97_0
      WBPaper00065841:117_0
      WBPaper00065841:128_0
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4489_group_13
      WBPaper00024671:AFD_AWB_vs_unsorted_upregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:Resveratrol_regulated_N2
      WBPaper00030839:Larval_Pan_Neuronal
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00031832:slr-2_regulated
      WBPaper00032165:differentially_expressed_with_age_medoid_2
      WBPaper00032948:StarveUp4
      WBPaper00034661:AgNPs_downregulated
      WBPaper00034739:N2moreDR1350
      WBPaper00035227:heat_shock_regulated
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00036123:Cadmium_regulated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_C
      WBPaper00038060:SUMO-1_downregulated
      WBPaper00038427:lin-54_embryo_changed
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040876:mir-35_downregulated
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:environmental_prime
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045263:ProLongevity-mtROS_upregulated
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00056330:mrps-5(RNAi)_upregulated
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc5976]:class_1
      [cgc6390]:Cluster_A
    Interaction (46)
  Map_info: Map: I Position: 1.09503 Error: 0.003632
    Positive: Positive_clone: T23H2 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4681
        5563
    Pseudo_map_position
  Reference: WBPaper00028592
    WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene