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WormBase Tree Display for Gene: WBGene00003735

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Name Class

WBGene00003735SMapS_parentSequenceY18D10A
IdentityVersion1
NameCGC_namenhx-8
Sequence_nameY18D10A.6
Molecular_nameY18D10A.6a
Y18D10A.6a.1
CE31092
Y18D10A.6b
CE31093
Y18D10A.6b.1
Other_nameCELE_Y18D10A.6Accession_evidenceNDBBX284601
Public_namenhx-8
DB_infoDatabaseAceViewgene1N425
WormQTLgeneWBGene00003735
WormFluxgeneWBGene00003735
NDBlocus_tagCELE_Y18D10A.6
PanthergeneCAEEL|WormBase=WBGene00003735|UniProtKB=G5EBN7
familyPTHR10110
NCBIgene189474
RefSeqproteinNM_001026557.4
NM_001026558.5
TREEFAMTREEFAM_IDTF354313
TrEMBLUniProtAccG5EBN7
G5EFN1
UniProt_GCRPUniProtAccG5EBN7
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:32WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnhx
Allele (184)
StrainWBStrain00002334
WBStrain00002723
WBStrain00031483
RNASeq_FPKM (74)
GO_annotation (21)
Ortholog (34)
ParalogWBGene00003729Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003730Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003731Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003732Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003733Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003734Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003736Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003943Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionnhx-8 encodes two isoforms of a sodium/proton exchanger expressed intracellularly within hypodermal seam cells, pharyngeal muscles, pharyngeal-intestinal and intestinal-rectal valve cells, and vulval cells; nhx-8 has no obvious phenotype in mass RNAi screens; NHX-8 is thought to prevent intracellular acidification by catalysing the electroneutral exchange of vesicular sodium for an intracellular proton.Paper_evidenceWBPaper00004402
WBPaper00005421
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport and regulation of intracellular pH. Predicted to be located in membrane. Expressed in several structures, including hypodermis; pharyngeal muscle cell; pharyngeal-intestinal valve; rectal valve cell; and vulva. Is an ortholog of human SLC9A8 (solute carrier family 9 member A8).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY18D10A.6a
Y18D10A.6b
Corresponding_CDS_historyY18D10A.6:wp80
Corresponding_transcriptY18D10A.6a.1
Y18D10A.6b.1
Other_sequence (44)
Associated_featureWBsf643780
WBsf656987
WBsf218643
Experimental_infoRNAi_resultWBRNAi00116504Inferred_automaticallyRNAi_primary
WBRNAi00055620Inferred_automaticallyRNAi_primary
WBRNAi00004546Inferred_automaticallyRNAi_primary
Expr_pattern (13)
Drives_constructWBCnstr00003003
WBCnstr00003255
WBCnstr00004498
WBCnstr00010716
WBCnstr00010727
Construct_productWBCnstr00010727
Microarray_results (23)
Expression_cluster (108)
Interaction (32)
Map_infoMapIPosition14.1387Error0.010006
PositivePositive_cloneY18D10AInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4534
5086
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00055090
WBPaper00066025
RemarkSequence connection from [Nehrke K, Melvin J]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
nxh-2 nxh-3 nxh-4 nxh-5 nxh-6 nxh-7 nxh-8 nxh-9 published in cgc5421 actually refer to nhx genesCGC_data_submission
MethodGene