WormBase Tree Display for Gene: WBGene00003732
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| WBGene00003732 | SMap | S_parent | Sequence | F14B8 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | nhx-4 | |||||||
| Sequence_name | F14B8.1 | ||||||||
| Molecular_name | F14B8.1a | ||||||||
| F14B8.1a.1 | |||||||||
| CE30951 | |||||||||
| F14B8.1b | |||||||||
| CE02644 | |||||||||
| F14B8.1b.1 | |||||||||
| Other_name | CELE_F14B8.1 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | nhx-4 | ||||||||
| DB_info | Database | AceView | gene | XH539 | |||||
| WormQTL | gene | WBGene00003732 | |||||||
| WormFlux | gene | WBGene00003732 | |||||||
| NDB | locus_tag | CELE_F14B8.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003732|UniProtKB=G5EDU2 | |||||||
| family | PTHR10110 | ||||||||
| NCBI | gene | 180964 | |||||||
| RefSeq | protein | NM_001029391.5 | |||||||
| NM_001381015.2 | |||||||||
| TREEFAM | TREEFAM_ID | TF317212 | |||||||
| TrEMBL | UniProtAcc | G5ECB7 | |||||||
| G5EDU2 | |||||||||
| UniProt_GCRP | UniProtAcc | G5EDU2 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | nhx | ||||||||
| Allele (192) | |||||||||
| Strain | WBStrain00031554 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Ortholog (49) | |||||||||
| Paralog | WBGene00003729 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00003730 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00003731 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00003736 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00003733 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00003735 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00003734 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00003943 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | nhx-4 encodes two isoforms of a sodium/proton exchanger expressed in the plasma membrane of nearly all cells and cell types; in polarized epithelial cells, NHX-4::GFP appears specifically located in the basolateral membrane, like human SLC9A1 ('NHE1'; OMIM:107310); nhx-4 has no reported mutant or RNAi phenotype, but, given its ubiquitous expression, may represent a housekeeping exchanger generally required for cellular viability; transgenic NHX-4A, when expressed in cell culture, mediates Na[+]-dependent pH recovery after intracellular acidification, independently of extracellular Cl[-]. | Paper_evidence | WBPaper00005421 | |||||
| WBPaper00005654 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport; regulation of intracellular pH; and sodium ion import across plasma membrane. Predicted to be located in plasma membrane. Expressed widely. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F14B8.1a | |||||||
| F14B8.1b | |||||||||
| Corresponding_transcript | F14B8.1a.1 | ||||||||
| F14B8.1b.1 | |||||||||
| Other_sequence | Oden_isotig18970 | ||||||||
| CBC14254_1 | |||||||||
| Dviv_isotig16028 | |||||||||
| Dviv_isotig16027 | |||||||||
| Acan_isotig07819 | |||||||||
| Associated_feature | WBsf662927 | ||||||||
| WBsf718617 | |||||||||
| WBsf1005679 | |||||||||
| WBsf1005680 | |||||||||
| WBsf1005681 | |||||||||
| WBsf235886 | |||||||||
| WBsf235887 | |||||||||
| WBsf235888 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00086171 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00086174 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00044576 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00030927 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr2244 | ||||||||
| Expr1021689 | |||||||||
| Expr1031743 | |||||||||
| Expr1148533 | |||||||||
| Expr2014256 | |||||||||
| Expr2032496 | |||||||||
| Drives_construct | WBCnstr00010724 | ||||||||
| WBCnstr00035909 | |||||||||
| Construct_product | WBCnstr00010724 | ||||||||
| WBCnstr00035909 | |||||||||
| Microarray_results (26) | |||||||||
| Expression_cluster (98) | |||||||||
| Interaction | WBInteraction000134079 | ||||||||
| WBInteraction000441533 | |||||||||
| Map_info | Map | X | Position | -2.00918 | Error | 0.028616 | |||
| Positive | Positive_clone | F14B8 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4441 | |||||||
| 4531 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005421 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Sequence connection from [Nehrke K, Melvin J] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| nxh-2 nxh-3 nxh-4 nxh-5 nxh-6 nxh-7 nxh-8 nxh-9 published in cgc5421 actually refer to nhx genes | CGC_data_submission | ||||||||
| Method | Gene |
