WormBase Tree Display for Gene: WBGene00003732
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WBGene00003732 | SMap | S_parent | Sequence | F14B8 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | nhx | ||||||
Allele (192) | |||||||
Strain | WBStrain00031554 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (18) | |||||||
Ortholog (49) | |||||||
Paralog | WBGene00003729 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
WBGene00003730 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00003731 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00003736 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00003733 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00003735 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00003734 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00003943 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
Structured_description | Concise_description | nhx-4 encodes two isoforms of a sodium/proton exchanger expressed in the plasma membrane of nearly all cells and cell types; in polarized epithelial cells, NHX-4::GFP appears specifically located in the basolateral membrane, like human SLC9A1 ('NHE1'; OMIM:107310); nhx-4 has no reported mutant or RNAi phenotype, but, given its ubiquitous expression, may represent a housekeeping exchanger generally required for cellular viability; transgenic NHX-4A, when expressed in cell culture, mediates Na[+]-dependent pH recovery after intracellular acidification, independently of extracellular Cl[-]. | Paper_evidence | WBPaper00005421 | |||
WBPaper00005654 | |||||||
Curator_confirmed | WBPerson567 | ||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
Automated_description | Predicted to enable potassium:proton antiporter activity and sodium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport; regulation of intracellular pH; and sodium ion import across plasma membrane. Predicted to be located in plasma membrane. Expressed widely. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F14B8.1a | |||||
F14B8.1b | |||||||
Corresponding_transcript | F14B8.1a.1 | ||||||
F14B8.1b.1 | |||||||
Other_sequence | Oden_isotig18970 | ||||||
CBC14254_1 | |||||||
Dviv_isotig16028 | |||||||
Dviv_isotig16027 | |||||||
Acan_isotig07819 | |||||||
Associated_feature | WBsf662927 | ||||||
WBsf718617 | |||||||
WBsf1005679 | |||||||
WBsf1005680 | |||||||
WBsf1005681 | |||||||
WBsf235886 | |||||||
WBsf235887 | |||||||
WBsf235888 | |||||||
Experimental_info | RNAi_result | WBRNAi00086171 | Inferred_automatically | RNAi_primary | |||
WBRNAi00086174 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00044576 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00030927 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr2244 | ||||||
Expr1021689 | |||||||
Expr1031743 | |||||||
Expr1148533 | |||||||
Expr2014256 | |||||||
Expr2032496 | |||||||
Drives_construct | WBCnstr00010724 | ||||||
WBCnstr00035909 | |||||||
Construct_product | WBCnstr00010724 | ||||||
WBCnstr00035909 | |||||||
Microarray_results (26) | |||||||
Expression_cluster (98) | |||||||
Interaction | WBInteraction000134079 | ||||||
WBInteraction000441533 | |||||||
Map_info | Map | X | Position | -2.00918 | Error | 0.028616 | |
Positive | Positive_clone | F14B8 | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 4441 | |||||
4531 | |||||||
Pseudo_map_position | |||||||
Reference | WBPaper00005421 | ||||||
WBPaper00038491 | |||||||
WBPaper00055090 | |||||||
Remark | Sequence connection from [Nehrke K, Melvin J] | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
nxh-2 nxh-3 nxh-4 nxh-5 nxh-6 nxh-7 nxh-8 nxh-9 published in cgc5421 actually refer to nhx genes | CGC_data_submission | ||||||
Method | Gene |