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WormBase Tree Display for Gene: WBGene00003096

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Name Class

WBGene00003096SMapS_parentSequenceC02A12
IdentityVersion1
NameCGC_namelys-7Person_evidenceWBPerson168
Sequence_nameC02A12.4
Molecular_nameC02A12.4
C02A12.4.1
CE07828
Other_nameCELE_C02A12.4Accession_evidenceNDBBX284605
Public_namelys-7
DB_infoDatabaseAceViewgene5D960
WormQTLgeneWBGene00003096
WormFluxgeneWBGene00003096
NDBlocus_tagCELE_C02A12.4
PanthergeneCAEEL|WormBase=WBGene00003096|UniProtKB=O16202
familyPTHR23208
NCBIgene178772
RefSeqproteinNM_071571.9
SwissProtUniProtAccO16202
TREEFAMTREEFAM_IDTF316378
UniProt_GCRPUniProtAccO16202
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:30WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classlys
Allele (30)
StrainWBStrain00031984
WBStrain00031985
WBStrain00004711
WBStrain00004740
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (20)
ParalogWBGene00003090Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00003091Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00003092Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003093Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003094Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003095Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003097Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00003098Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003099Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionlys-7 encodes an enzyme homologous to an antimicrobial lysozyme encoded by the LYS4 gene of the protozoan parasite Entamoeba histolytica; LYS-7 functions in the innate immune response as an antimicrobial enzyme that, by homology, hydrolyzes the 1,4-beta-linkages between N-acetyl-D-glucosamine and N-acetylmuramic acid in peptidoglycan heteropolymers of prokaryotic cell walls; loss of lys-7 activity results in enhanced susceptibility to P. aeruginosa PA14, renders worms susceptible to Cryptococcus neoformans killing, but enhances tolerance to the enteric bacteria Salmonella typhimurium; lys-7 expression is significantly upregulated in response to infection with the Gram-negative bacterium Serratia marcescens; constitutive expression of lys-7 mRNA is detected in the intestine and the intestinal valve cells.Paper_evidenceWBPaper00004651
WBPaper00005382
WBPaper00005569
WBPaper00005654
WBPaper00041211
WBPaper00038223
WBPaper00032276
Curator_confirmedWBPerson1843
Date_last_updated19 Feb 2014 00:00:00
Automated_descriptionInvolved in defense response to other organism. Expressed in head neurons; intestine; and rectal gland cell.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC02A12.4
Corresponding_transcriptC02A12.4.1
Other_sequence (84)
Associated_featureWBsf019148
WBsf019149
WBsf652532
WBsf233493
WBsf233494
Experimental_infoRNAi_result (21)
Expr_patternExpr1973
Expr4716
Expr10716
Expr1018008
Expr1143497
Expr2013318
Expr2031549
Drives_constructWBCnstr00009965
WBCnstr00012193
WBCnstr00015892
WBCnstr00017492
WBCnstr00036232
WBCnstr00041439
Construct_productWBCnstr00009965
WBCnstr00012193
WBCnstr00036232
Microarray_results (18)
Expression_cluster (437)
Interaction (200)
WBProcessWBbiopr:00000008
WBbiopr:00000039
Map_infoMapVPosition-10.8998Error0.024633
PositivePositive_cloneC02A12Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4881
4924
5423
Pos_neg_data10776
Pseudo_map_position
ReferenceWBPaper00005382
WBPaper00005569
WBPaper00005976
WBPaper00006302
WBPaper00006437
WBPaper00024209
WBPaper00025180
WBPaper00027295
WBPaper00027722
WBPaper00029438
WBPaper00031095
WBPaper00031802
WBPaper00032232
WBPaper00032276
WBPaper00032331
WBPaper00032370
WBPaper00033781
WBPaper00036474
WBPaper00036653
WBPaper00037128
WBPaper00038100
WBPaper00038223
WBPaper00038503
WBPaper00038506
WBPaper00040118
WBPaper00040174
WBPaper00040209
WBPaper00040287
WBPaper00040389
WBPaper00040549
WBPaper00041211
WBPaper00041339
WBPaper00041525
WBPaper00042276
WBPaper00042367
WBPaper00043135
WBPaper00044718
WBPaper00045438
WBPaper00046040
WBPaper00047109
WBPaper00048424
WBPaper00050428
WBPaper00053417
WBPaper00055320
WBPaper00056410
WBPaper00057299
WBPaper00057414
WBPaper00058665
WBPaper00059715
WBPaper00061133
WBPaper00061774
WBPaper00062392
WBPaper00064183
WBPaper00064229
WBPaper00064255
WBPaper00064370
WBPaper00064543
WBPaper00064639
WBPaper00064841
WBPaper00064950
WBPaper00065026
WBPaper00065034
WBPaper00065681
WBPaper00065718
WBPaper00066310
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene