WormBase Tree Display for Gene: WBGene00003090
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| WBGene00003090 | SMap | S_parent | Sequence | Y22F5A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | lys-1 | Person_evidence | WBPerson168 | |||||
| Sequence_name | Y22F5A.4 | ||||||||
| Molecular_name | Y22F5A.4 | ||||||||
| Y22F5A.4.1 | |||||||||
| CE16605 | |||||||||
| Other_name | CELE_Y22F5A.4 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | lys-1 | ||||||||
| DB_info | Database | AceView | gene | 5K759 | |||||
| WormQTL | gene | WBGene00003090 | |||||||
| WormFlux | gene | WBGene00003090 | |||||||
| NDB | locus_tag | CELE_Y22F5A.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00003090|UniProtKB=O62415 | |||||||
| family | PTHR23208 | ||||||||
| NCBI | gene | 179428 | |||||||
| RefSeq | protein | NM_073241.7 | |||||||
| SwissProt | UniProtAcc | O62415 | |||||||
| TREEFAM | TREEFAM_ID | TF316378 | |||||||
| UniProt_GCRP | UniProtAcc | O62415 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:30 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | lys | ||||||||
| Allele (22) | |||||||||
| Strain | WBStrain00032578 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (13) | |||||||||
| Ortholog (33) | |||||||||
| Paralog | WBGene00003091 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00003096 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00003097 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00003092 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00003098 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00003093 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00003099 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00003094 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00003095 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | lys-1 encodes a putative lysozyme, whose overexpression increasesresistance to infection by Serratia marcescens; lys-1(RNAi) animals havenormal resistance to S. marcescens, perhaps because of geneticredundancy with the LYS-1 paralogs LYS-2 to -8 and LYS-10; in uninfectedanimals, LYS-1 is expressed in the intestine and in IL1/IL2 neurons,along with a few unidentified head neurons; in intestinal cells, LYS-1localizes to apical vesicles; LYS-1 expression is induced by infectionby Pseudomonas aeruginosa but not S. marcescens; LYS-1 expression ispromoted by DBL-1, TIR-1 and NSY-1, and perhaps also by ELT-2, but notby DAF-16; LYS-1 and its paralogs are more similar to lysozymes from theamoeboid protozoon Entamoeba histolytica than to more familiar ones fromvertebrates. | Paper_evidence | WBPaper00005382 | |||||
| WBPaper00028482 | |||||||||
| WBPaper00029438 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 31 May 2007 00:00:00 | ||||||||
| Automated_description | Involved in defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; and innate immune response. Located in apical part of cell and cytoplasmic vesicle. Expressed in intestine and neurons. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y22F5A.4 | |||||||
| Corresponding_transcript | Y22F5A.4.1 | ||||||||
| Other_sequence (57) | |||||||||
| Associated_feature | WBsf647149 | ||||||||
| WBsf661620 | |||||||||
| WBsf661621 | |||||||||
| WBsf1001086 | |||||||||
| WBsf1001087 | |||||||||
| WBsf1020290 | |||||||||
| WBsf1020291 | |||||||||
| WBsf232353 | |||||||||
| WBsf232354 | |||||||||
| WBsf232355 | |||||||||
| Gene_product_binds | WBsf978958 | ||||||||
| WBsf978961 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00085305 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00055691 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00085307 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00075994 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00111756 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090662 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00020122 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1972 | ||||||||
| Expr1975 | |||||||||
| Expr4715 | |||||||||
| Expr1027200 | |||||||||
| Expr1031464 | |||||||||
| Expr1159217 | |||||||||
| Expr2013312 | |||||||||
| Expr2031543 | |||||||||
| Drives_construct | WBCnstr00010553 | ||||||||
| WBCnstr00012192 | |||||||||
| WBCnstr00015890 | |||||||||
| WBCnstr00015922 | |||||||||
| WBCnstr00015926 | |||||||||
| WBCnstr00015927 | |||||||||
| WBCnstr00015929 | |||||||||
| WBCnstr00036238 | |||||||||
| Construct_product | WBCnstr00010553 | ||||||||
| WBCnstr00012192 | |||||||||
| WBCnstr00036238 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (308) | |||||||||
| Interaction (141) | |||||||||
| WBProcess | WBbiopr:00000008 | ||||||||
| WBbiopr:00000039 | |||||||||
| WBbiopr:00000092 | |||||||||
| Map_info | Map | V | Position | 2.4495 | Error | 0.001114 | |||
| Positive | Positive_clone | Y22F5A | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (35) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
