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WormBase Tree Display for WBProcess: WBbiopr:00000057

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Name Class

WBbiopr:00000057Public_nameRNA interference
SummaryRNA interference (RNAi) refers to the silencing of gene expression by the overexpression of RNA molecules. This process is associated with a cellular and nuclear defense mechanism used to combat molecular parasites such as transposons and viruses. In addition, RNA interference has been shown to play a regulatory role in development. Work in C. elegans and other organisms have identified many key regulators and pathways necessary for this process. Specifically, RNAi has been adapted into a tool for the study of gene function; through the use of RNAi, the expression of a target gene can be inhibited by the reverse engineering of a corresponding dsRNA.
Other_nameGene silencing
RNAi
Gene inactivation
Post transcriptional gene silencing
Related_topicSpecialisation_ofWBbiopr:00000037
Involved_entityGeneWBGene00004508
WBGene00004509
WBGene00001332Paper_evidenceWBPaper00027057
WBGene00000939Paper_evidenceWBPaper00027057
WBGene00004323
WBGene00004326Paper_evidenceWBPaper00027057
WBGene00021103Paper_evidenceWBPaper00027057
WBGene00001214
WBGene00003508
WBGene00011908
WBGene00022620Paper_evidenceWBPaper00046393
WBGene00003003Paper_evidenceWBPaper00040098
WBGene00021419Paper_evidenceWBPaper00027057
WBGene00004093
WBGene00009163
WBGene00000106Paper_evidenceWBPaper00027057
WBGene00008400Paper_evidenceWBPaper00027057
WBGene00003026
WBGene00002993Paper_evidenceWBPaper00040098
WBGene00002285
WBGene00004510Paper_evidenceWBPaper00027057
WBGene00006924
WBGene00006626
WBGene00003504
WBGene00003499Paper_evidenceWBPaper00046393
WBGene00003014
WBGene00000105Paper_evidenceWBPaper00027057
Expression_cluster (2)
Interaction (81)
Anatomy_termWBbt:0005784Paper_evidenceWBPaper00031477
Associated_withGO_termGO:0016246
PathwayDB_infoDatabaseWikiPathwaysPathwayWP394
Remark"WikiPathways" "Pathway" "WP394"
ReferenceWBPaper00003670
WBPaper00027057
WBPaper00031477
WBPaper00038519
WBPaper00040098
WBPaper00046393