F09F7.5 encodes, by alternative splicing, three isoforms of an unfamiliar protein required for in conjunction with LIN-35 for normally large brood size, in conjunction with CLK-2 for normally rapid growth, and for normally short lifespan; F09F7.5 binds equally well to Cdc42 and Rac GTPases in vitro, probably through its N-terminal P21-Rho-binding domain; F09F7.5 has no obvious orthologs outside of Caenorhabditis species, and aside from its N-terminus is interspersed with low-complexity residues.
Predicted to enable small GTPase binding activity. Predicted to be involved in regulation of Rho protein signal transduction and regulation of cell shape. Predicted to be located in cytoskeleton and plasma membrane. Is an ortholog of human CDC42SE1 (CDC42 small effector 1) and CDC42SE2 (CDC42 small effector 2).