WormBase Tree Display for Gene: WBGene00007969

WBGene00007969 SMap: S_parent: Sequence: C36A4
  Identity: Version: 2
    Name: CGC_name: acs-19 Person_evidence: WBPerson237
            WBPerson2239
      Sequence_name: C36A4.9
      Molecular_name (6)
      Other_name: CELE_C36A4.9 Accession_evidence: NDB BX284603
      Public_name: acs-19
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:48 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 11 Sep 2008 09:57:25 WBPerson2970 Name_change: CGC_name: acs-19
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: acs
    Allele (29)
    Strain: WBStrain00001428
      WBStrain00001280
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog (43)
    Paralog: WBGene00006351 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00009221 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00012356 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00013440 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00016849 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00018269 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00018488 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00018579 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable acetate-CoA ligase activity. Involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and regulation of response to oxidative stress. Expressed in hypodermis; intestine; neurons; and pharynx. Human ortholog(s) of this gene implicated in lymphangioleiomyomatosis; morbid obesity; and orofacial cleft. Is an ortholog of human ACSS2 (acyl-CoA synthetase short chain family member 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:3319 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:15814)
      DOID:0050567 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:15814)
      DOID:11981 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:15814)
  Molecular_info: Corresponding_CDS: C36A4.9a
      C36A4.9b
    Corresponding_transcript: C36A4.9a.1
      C36A4.9b.1
    Other_sequence (168)
    Associated_feature (13)
  Experimental_info: RNAi_result (12)
    Expr_pattern (12)
    Drives_construct: WBCnstr00002175
      WBCnstr00004245
      WBCnstr00011939
      WBCnstr00021141
      WBCnstr00033341
      WBCnstr00042511
    Construct_product: WBCnstr00033341
    Microarray_results (28)
    Expression_cluster: WBPaper00028802:intestine_unique
      WBPaper00029359_1142
      WBPaper00029359_1187
      WBPaper00029359_1217
      WBPaper00029359_1280
      WBPaper00029359_1444
      WBPaper00029359_1504
      WBPaper00029359_1524
      WBPaper00029359_1604
      WBPaper00032097:CGH-1-associated-mRNA
      WBPaper00032528:L3_enriched
      WBPaper00033070:Elbe_upregulated
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:CEP-sheath-cells_adult_enriched
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:germline-precursors_embryo_enriched
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038213:E.coli(LF82)_24h_upregulated
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00040209:B.thuringiensis_downregulated_MY18
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00040412:germline-regulated_daf-16_target
      WBPaper00041370:spg-7(RNAi)_upregulated_atfs-1_dependent
      WBPaper00044037:eat-2_downregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
      WBPaper00045050:csr-1(hypomorph)_downregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045729:gld-2(RNAi)_downregulated
      WBPaper00045774:clk-1_upregulated
      WBPaper00045774:clk-1_upregulated_CoQ10_independent
      WBPaper00046024:sleep_downregulated_oscillating
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049905:Age_variant_expression
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050015:ifg-1(RNAi)_upregulated
      WBPaper00050163:chd-3(eh4)_downregulated_100-cell-embryo
      WBPaper00050412:cco-1(RNAi)_upregulated_N2
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053295:lin-22(ot267)_downregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:stavudine_72h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00054192:cold-shock_downregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rapamycin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055565:AVK_enriched
      WBPaper00055648:germline_expressed
      WBPaper00055971:nhl-2(ok818)_20C_downregulated
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00057288:Cold_downregulated_protein
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00059174:MEG-3_interacting
      WBPaper00059194:KLF-1_interacting
      WBPaper00059253:stearic-acid_upregulated
      WBPaper00059253:sucrose_stearic-acid_upregulated
      WBPaper00059253:sucrose_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059426:Ag-nanoparticles_upregulated
      WBPaper00059471:EGL-43_interacting
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060434:pH4.33_vs_pH6.33_uprgulated
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00060871:M.humicola-extract_1h_regulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061274:hypergravity_15xg_upregulated
      WBPaper00061340:ALN
      WBPaper00061340:DVC
      WBPaper00061527:W01F3.2_1554-Y106G6D.8
      WBPaper00061651:CAN_enriched
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:AFD_depleted
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065746:eat-2(ad1113)_upregulated
      WBPaper00065841:22_0
      WBPaper00066038:mip-1(how5)_upregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066204:CdCl2_downregulated_mRNA
      cgc4386_cluster_1_1
      cgc4489_group_12
      WBPaper00025032:cluster_1
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026952:class_F
      WBPaper00026980:intestine_enriched
      WBPaper00030985:Photorhabdus_luminescens_upregulated
      WBPaper00032165:A_to_C_transit_decreased
      WBPaper00032948:StarveUp3
      WBPaper00036286:Pattern_F
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040963:Q50_up
      WBPaper00040963:TA300_down
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00042178:hlh-29(tm284)_upregulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045673:colistin_upregulated
      WBPaper00048624:hlh-25(ok1710)_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00048989:N2_allantoin_downregulated
      WBPaper00049311:Ag-MNP_regulated
      WBPaper00050538:Fasting_upregulated
      WBPaper00050538:Fasting_upregulated_cholesterol-dependent
      WBPaper00053236:daf-16(mgDF50)_regulated_Starved
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053550:daf-19(m86)_upregulated_L1
      [cgc5767]:cluster_1
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MD_pd(41_min)
      [cgc5767]:expression_class_MD_pd(53_min)
      [cgc5767]:expression_class_SM
      [cgc5767]:expression_class_SMD
    Interaction (93)
  Map_info: Map: III Position: -4.24766 Error: 0.000156
    Positive: Positive_clone: C36A4 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (11)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene