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WormBase Tree Display for Gene: WBGene00003864

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Name Class

WBGene00003864SMapS_parentSequenceCHROMOSOME_IV
IdentityVersion1
NameCGC_nameoma-1Person_evidenceWBPerson374
Sequence_nameC09G9.6
Molecular_nameC09G9.6
C09G9.6.1
CE03005
Other_namemoe-1
CELE_C09G9.6Accession_evidenceNDBBX284604
Public_nameoma-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classoma
AlleleWBVar02148557
WBVar02157708
WBVar02158382
WBVar02158384
WBVar02158386
WBVar02158387
WBVar02158385
WBVar00431236
WBVar00431237
WBVar00275548
WBVar00431238
WBVar01500079
WBVar02058224
WBVar01498996
WBVar01854985
WBVar01854986
WBVar01854987
WBVar01854988
WBVar01854989
WBVar01854990
WBVar02134342
WBVar00090978
WBVar01730266
WBVar01730267
WBVar00929046
WBVar01499633
WBVar00929047
WBVar00249247
WBVar00929048
WBVar00249248
WBVar00249249
WBVar00929049
WBVar00249250
WBVar00929050
WBVar00929051
WBVar00249251
WBVar00249252
WBVar00929052
WBVar00249253
WBVar00929053
WBVar00249254
WBVar00929054
WBVar00929055
WBVar00249255
WBVar00929056
WBVar00249256
WBVar00929057
WBVar00929058
WBVar00929059
WBVar00929060
WBVar00091009
WBVar00250389
WBVar01498928
WBVar01500245
WBVar00431234
WBVar00431235
StrainWBStrain00035069
WBStrain00035066
WBStrain00035067
WBStrain00035068
WBStrain00040433
WBStrain00040434
WBStrain00048324
WBStrain00052677
RNASeq_FPKM (74)
GO_annotation (55)
Contained_in_operonCEOP4312
Ortholog (51)
Paralog (20)
Structured_descriptionConcise_descriptionoma-1 encodes a zinc finger protein of the TIS11 finger type that is paralogous to OMA-2; while either oma-1 or oma-2 individually have no obvious mutant phenotype, oma-1 and oma-2 doubly mutant animals show defects in oocyte maturation, indicating that the two genes function redundantly in this process; whereas normal oocytes are released from meiotic prophase I arrest during oocyte maturation, oma-1;oma-2 mutant oocytes initiate, but fail to complete, maturation, arresting at a defined point in meiotic prophase I; the meiotic arrest of oma-1;oma-2 mutant oocytes is suppressed by wee-1.3(RNAi), implying that progression through meiotic prophase I is critically dependent on inhibition of WEE-1.3 by either OMA-1 or OMA-2; OMA-1 is expressed primarily in maturing oocytes, is cytoplasmic and visible prior to cellularization.Paper_evidenceWBPaper00005198
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated19 Mar 2012 00:00:00
Automated_descriptionEnables mRNA 3'-UTR AU-rich region binding activity and mRNA regulatory element binding translation repressor activity. Involved in several processes, including negative regulation of cell differentiation; oocyte development; and regulation of reproductive process. Located in P granule and centrosome. Part of messenger ribonucleoprotein complex. Expressed in several structures, including head muscle; neurons; oocyte; somatic nervous system; and vulva. Is an ortholog of human ZFP36L1 (ZFP36 ring finger protein like 1) and ZFP36L2 (ZFP36 ring finger protein like 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelEFO:MONDO:0014769Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1108)
Molecular_infoCorresponding_CDSC09G9.6
Corresponding_transcriptC09G9.6.1
Other_sequenceXIC01512_1
HG11531
XI03775
SRC08713_1
FC813056.1
Associated_feature (15)
Gene_product_bindsWBsf034245
Transcription_factorWBTranscriptionFactor000116
Experimental_infoRNAi_result (29)
Expr_pattern (16)
Drives_construct (13)
Construct_product (14)
AntibodyWBAntibody00000486
WBAntibody00000547
WBAntibody00001073
WBAntibody00001074
WBAntibody00001087
WBAntibody00001664
WBAntibody00002447
Microarray_results (20)
Expression_cluster (207)
Interaction (354)
WBProcessWBbiopr:00000068
WBbiopr:00000073
Map_info (3)
Reference (94)
PictureWBPicture0000013094
RemarkWeak rescue of the zu405 embryonic lethality [Lin, R][021017 ck1]
Sequence connection based on Lin, R [021017 ck1]
Sequence connection from [Shimada M], [krb 020711]
Postitive method is weak rescue of the zu405 embryonic lethality
MethodGene