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WormBase Tree Display for WBProcess: WBbiopr:00000068

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Name Class

WBbiopr:00000068Public_nameOogenesis
SummaryOogenesis is the process of generating functional oocytes from an undifferentiated germ cell. In most animal species, oocytes arrest during meiotic prophase. The completion of meiosis and the preparation of the oocyte for fertilization are triggered in response to intercellular signaling in a process called meiotic maturation. During meiotic maturation, the oocyte transitions to metaphase of meiosis I, the nuclear envelope breaks down, the cortical cytoskeleton undergoes rearrangement, and the meiotic spindle is assembled. By contrast, in C. elegans, the processes of meiotic maturation, ovulation, and fertilization are temporally coupled. Meiotic maturation is triggered by major sperm protein (MSP), which acts as a hormone. In turn the maturing oocyte signals its own ovulation. During ovulation the oocyte passes through the spermatheca becoming fertilized on the way to the uterus.
Related_topicSpecialisation_ofWBbiopr:00000067
WBbiopr:00000131
Involved_entityGene (14)
InteractionWBInteraction000540326
WBInteraction000540353
WBInteraction000540354
WBInteraction000556283
Associated_withGO_termGO:0048477
ReferenceWBPaper00004905
WBPaper00027238
WBPaper00045521