WormBase Tree Display for Gene: WBGene00017302

WBGene00017302 SMap: S_parent: Sequence: F09F7
  Identity: Version: 1
    Name: Sequence_name: F09F7.5
      Molecular_name: F09F7.5a
        F09F7.5a.1
        CE01237
        F09F7.5b
        CE29259
        F09F7.5a.2
        F09F7.5b.1
        F09F7.5b.2
      Other_name: CELE_F09F7.5 Accession_evidence: NDB BX284603
      Public_name: F09F7.5
    DB_info: Database: AceView gene 3G639
        WormQTL gene WBGene00017302
        WormFlux gene WBGene00017302
        NDB locus_tag CELE_F09F7.5
        Panther gene CAEEL|WormBase=WBGene00017302|UniProtKB=Q19275
          family PTHR13502
        NCBI gene 175764
        RefSeq protein NM_065785.8
            NM_001392099.1
        TrEMBL UniProtAcc H2KZJ0
            Q19275
        UniProt_GCRP UniProtAcc Q19275
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:58 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele: WBVar00093024
      WBVar01500260
      WBVar02132045
      WBVar01644754
      WBVar01644755
      WBVar01500122
      WBVar01500123
      WBVar01999608
      WBVar00398185
      WBVar00398186
      WBVar02018831
      WBVar00398187
      WBVar00398188
      WBVar00398189
      WBVar00398190
      WBVar00398191
      WBVar00398192
      WBVar02010501
      WBVar00398193
      WBVar00828291
      WBVar00828292
      WBVar00828293
      WBVar00828294
      WBVar00828295
      WBVar00828296
      WBVar01566418
      WBVar00828297
      WBVar00828298
      WBVar00828299
      WBVar00828300
      WBVar00828301
      WBVar00828302
      WBVar00828303
      WBVar00828304
      WBVar00828305
      WBVar00828306
      WBVar00828307
      WBVar00828308
      WBVar00828309
      WBVar00828310
      WBVar00828311
      WBVar00828312
      WBVar00828313
      WBVar01263721
      WBVar00828314
      WBVar01263722
      WBVar00828315
      WBVar01263723
      WBVar00828316
      WBVar00828317
      WBVar01263724
      WBVar00828318
      WBVar01263725
      WBVar00828319
      WBVar02055730
      WBVar00828320
      WBVar00828321
      WBVar00828322
      WBVar00828323
      WBVar00828324
      WBVar00828325
      WBVar00828326
      WBVar00828327
      WBVar00828328
      WBVar00828329
      WBVar00828330
      WBVar01479778
      WBVar01479779
      WBVar01500030
      WBVar01500031
      WBVar01893415
      WBVar00060827
    Strain: WBStrain00036518
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog (32)
    Structured_description: Concise_description: F09F7.5 encodes, by alternative splicing, three isoforms of an unfamiliar protein required for in conjunction with LIN-35 for normally large brood size, in conjunction with CLK-2 for normally rapid growth, and for normally short lifespan; F09F7.5 binds equally well to Cdc42 and Rac GTPases in vitro, probably through its N-terminal P21-Rho-binding domain; F09F7.5 has no obvious orthologs outside of Caenorhabditis species, and aside from its N-terminus is interspersed with low-complexity residues. Paper_evidence: WBPaper00026643
            WBPaper00029258
            WBPaper00031036
            WBPaper00032021
          Curator_confirmed: WBPerson567
          Date_last_updated: 24 Jul 2008 00:00:00
      Automated_description: Predicted to enable small GTPase binding activity. Predicted to be involved in regulation of Rho protein signal transduction and regulation of cell shape. Predicted to be located in cytoskeleton and plasma membrane. Is an ortholog of human CDC42SE1 (CDC42 small effector 1) and CDC42SE2 (CDC42 small effector 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F09F7.5a
      F09F7.5b
    Corresponding_CDS_history: F09F7.5c:wp275
    Corresponding_transcript: F09F7.5a.1
      F09F7.5a.2
      F09F7.5b.1
      F09F7.5b.2
    Other_sequence: CBC02919_1
      CR03845
      CRC05111_1
      CJC16954_1
    Associated_feature: WBsf645179
      WBsf658956
      WBsf992437
      WBsf992438
      WBsf1014905
      WBsf1014906
      WBsf224945
      WBsf224946
  Experimental_info: RNAi_result (13)
    Expr_pattern: Expr1028990
      Expr1037436
      Expr1148124
      Expr2002354
      Expr2020572
    Drives_construct: WBCnstr00027408
    Construct_product: WBCnstr00027408
    Microarray_results (33)
    Expression_cluster: WBPaper00033070:Elbe_downregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044030:nhr-8(hd117)_upregulated
      WBPaper00044316:CH3HgCl_7.5uM_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045521:Gender_Neutral
      WBPaper00046121:endoderm_unique
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048690:hermaphrodite-Z1-Z4-daughter_enriched
      WBPaper00048690:hermaphrodite-Z1-Z4_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049217:TCER-1_downregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00050332:skn-1(RNAi)_downregulated
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051245:cytoplasm_specific
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_specific
      WBPaper00051305:vit-2(ac3)_upregulated
      WBPaper00051558:fog-2(q71)_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053020:sid-3(ok973)_upregulated
      WBPaper00053094:adr-2(ok735)_neuron_downregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00054192:cold-shock_upregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056167:Cry5B_downregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056826:SGP_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057347:nhr-14(tm1473)_upreglated
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058711:paraquat_downregulated
      WBPaper00058725:sftb-1(cer39)_downregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00058958:100mGy-irradiation-72h_upregulated
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059567:olrn-1(ums9)_regulated
      WBPaper00059604:fluvastatin_downregulated_dlk-1(km12)
      WBPaper00059604:fluvastatin_downregulated_N2
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059739:hira-1(gk835598)_upregulated_adult
      WBPaper00059754:C.neoformans_H99_upregulated
      WBPaper00059895:wounding_upregulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060100:SiNP_upregulated_mRNA
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061081:E.faecalis_upregulated_N2
      WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:AVJ
      WBPaper00061478:pie-1(ne4433)_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061527:C10C5.2-Y58A7A.3
      WBPaper00061527:sre-33-ZK1025.1_8337
      WBPaper00061530:nhr-49(e2144)_upregulated
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062184:PA14_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00064494:postdauer_downregulated_AWA
      WBPaper00064637:cox-5B(RNAi)_upregulated
      WBPaper00065029:cadmium_upregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065734:unc-25(e156)_upregulated
      WBPaper00065749:Heat-Shock-With-Recovery_upregulated_N2
      WBPaper00065841:10_0
      WBPaper00065841:50_0
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      cgc4386_cluster_3_3
      WBPaper00025099:MA_specific
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Enriched_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026980:intestine_enriched
      WBPaper00030839:Embryo_A_Class
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035891:zip-2(RNAi)_downregulated
      WBPaper00036123:Atrazine_regulated
      WBPaper00037695:WC_5-day
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041267:SpaceFlight_Downregulated
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041906:I-3690_vs_OP50_3d
      WBPaper00041939:control_vs_UVC-EtBr-exposed_3h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_24h
      WBPaper00045673:colistin_upregulated
      WBPaper00046548:dafachronic-acid_downregulated
      WBPaper00047070:DAF-16-dependent_UV_response
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00048989:N2_allantoin_downregulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
      [cgc6390]:Cluster_B
    Interaction (82)
  Map_info: Positive: Positive_clone: F09F7 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: III -1.55252
  Reference: WBPaper00032021
  Method: Gene