WormBase Tree Display for Gene: WBGene00018488

WBGene00018488 SMap: S_parent: Sequence: F46E10
  Identity: Version: 2
    Name: CGC_name: acs-1 Paper_evidence: WBPaper00024532
          Person_evidence: WBPerson2239
            WBPerson237
      Sequence_name: F46E10.1
      Molecular_name: F46E10.1a
        F46E10.1a.1
        CE20812
        F46E10.1b
        CE37771
        F46E10.1c
        CE37772
        F46E10.1b.1
        F46E10.1c.1
      Other_name: CELE_F46E10.1 Accession_evidence: NDB BX284605
      Public_name: acs-1
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:00 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 29 Aug 2008 15:45:20 WBPerson2970 Name_change: CGC_name: acs-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: acs
    Allele (103)
    Strain: WBStrain00037525
    Component_of_genotype: WBGenotype00000151
      WBGenotype00000152
      WBGenotype00000153
    RNASeq_FPKM (74)
    GO_annotation: 00081430
      00081431
      00100721
    Ortholog (40)
    Paralog: WBGene00009221 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00016849 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00018269 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00018579 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00006351 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00007969 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00012356 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00013440 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable medium-chain fatty acid-CoA ligase activity. Involved in establishment or maintenance of epithelial cell apical/basal polarity. Expressed in gonad; intestine; neurons; and seam cell. Is an ortholog of human ACSF2 (acyl-CoA synthetase family member 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F46E10.1a
      F46E10.1b
      F46E10.1c
    Corresponding_CDS_history: F46E10.1:wp135
    Corresponding_transcript: F46E10.1a.1
      F46E10.1b.1
      F46E10.1c.1
    Other_sequence (41)
    Associated_feature (15)
  Experimental_info: RNAi_result (47)
    Expr_pattern: Expr4358
      Expr10000
      Expr16046
      Expr1022914
      Expr1037969
      Expr1151360
      Expr2009209
      Expr2027446
    Drives_construct: WBCnstr00001759
      WBCnstr00011941
      WBCnstr00014997
      WBCnstr00026477
    Construct_product: WBCnstr00014997
      WBCnstr00026477
    Microarray_results (31)
    Expression_cluster: WBPaper00028802:intestine_unique
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032528:L3_enriched
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037950:germline-precursors_embryo_enriched
      WBPaper00037950:hypodermis_embryo_enriched
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00038168:lin-35_downregulated
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040134:nhr-49(RNAi)_regulated_protein
      WBPaper00040990:PA14_downregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00045390:ubc-9(RNAi)_upregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00046024:sleep_downregulated_oscillating
      WBPaper00046415:lithium_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_downregulated_protein
      WBPaper00046795:starvation_downregulated
      WBPaper00046887:WNT-target
      WBPaper00048810:CoQ-deficiency_downregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048971:daf-16(mgDf50)_upregulated_L1
      WBPaper00048988:neuron_expressed
      WBPaper00049495:starvation-refeeding_regulated
      WBPaper00049498:npr-1(ur89)_regulated_3
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049905:Age_variant_expression
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050686:glp-1(e2141)_upregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00051257:Levamisole_downregulated
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00051404:alg-2(ok304)_downregulated
      WBPaper00052987:UV_downregulated_xpc-1;csb-1
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053295:lin-22(ot267)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053599:female_vs_male_upregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053664:ins-11(tm1053)_downregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053810:sod-2(ok1030)_downregulated
      WBPaper00053814:OP50_vs_PY79_upregulated_PY79
      WBPaper00055049:S.gordonii_downregulated
      WBPaper00055137:S.maltophilia_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055482:Tunicamycin_downregulated
      WBPaper00055565:AVK_enriched
      WBPaper00055969:electromagnetic-field_downregulated
      WBPaper00055971:nhl-2(ok818)_20C_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056039:efa-6(tm3124)_upregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056139:gut-microbiota_upregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056284:ints-1(RNAi)_upregulated
      WBPaper00056293:rpl-5(0)-rpl-33(0)_downregulated
      WBPaper00056443:DietaryRestriction_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057254:MWCNT_downregulated_mRNA
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:set-2(bn129)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059117:B.subtilis_downregulated
      WBPaper00059253:sucrose_stearic-acid_upregulated
      WBPaper00059253:sucrose_upregulated
      WBPaper00059426:Ag-nanoparticles_upregulated
      WBPaper00059739:hira-1(gk835598)_downregulated_adult
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059895:wounding_downregulated
      WBPaper00059987:Wounding_downregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_lin-40(yth27)
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060100:SiNP_upregulated_mRNA
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_N2
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061007:X.citri_downregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:AVB
      WBPaper00061340:DVA
      WBPaper00061340:Seam_cell
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061424:Diet_MYb120_downregulated
      WBPaper00061466:nath-10(icb102)_downregulated
      WBPaper00061527:R10H10.3-T21H3.1
      WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_downregulated
      WBPaper00061651:AVA_enriched
      WBPaper00061651:AVB_enriched
      WBPaper00061651:RIV_enriched
      WBPaper00061651:SDQ_enriched
      WBPaper00061753:csr-1(tor159)_downregulated_25C
      WBPaper00062095:unc-4(e120)_upregulated_VA-neuron
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_downregulated_N2
      WBPaper00062345:bortezomib_4h_downregulated_zip-1(jy13)
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062440:crh-1(n3315)_upregulated
      WBPaper00062440:crh-1(syb385)_upregulated
      WBPaper00062456:doxycycline_downregulated_N2_protein
      WBPaper00062456:doxycycline_upregulated_CB4856_protein
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00062684:pathogen_downregulated_N2
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064130:Beta-Amyloid_upregulated_protein
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064505:tamoxifen_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064728:cpl-1(W32AY35A)_upregulated
      WBPaper00064769:him-17(me24)_upregulated
      WBPaper00064871:hypoxia_upregulated_F1
      WBPaper00065086:JU1400_N.ausubeli_regulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:AFD_depleted
      WBPaper00065225:nhr-42(tm1375)_downregulated_S.aureus-infected
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065373:sek-1(km4)_downregulated_Ref
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:18_0
      WBPaper00065841:19_0
      WBPaper00065841:22_0
      WBPaper00065841:33_1
      WBPaper00065841:46_0
      WBPaper00065841:51_0
      WBPaper00065841:51_1
      WBPaper00065841:61_0
      WBPaper00065841:69_0
      WBPaper00065841:76_0
      WBPaper00065841:86_0
      WBPaper00065841:103_0
      WBPaper00065841:130_0
      WBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein
      WBPaper00065945:epidermis-rpoa-2(-)_upregulated_transcript
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066085:sin-3(syb2172)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_1_3
      cgc4489_group_3
      WBPaper00005124:progesterone_10-5M_regulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00028789:PA14_vs_OP50_downregulated_4hr
      WBPaper00030985:Photorhabdus_luminescens_downregulated
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031252:AIN-2_IP_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00032062:age_regulated_genes
      WBPaper00032165:differentially_expressed_with_age_medoid_6
      WBPaper00032948:FedUp
      WBPaper00035227:heat_shock_regulated
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00036286:Pattern_C
      WBPaper00036464:S.aureus-RN6390_regulated
      WBPaper00037695:WC_5-day
      WBPaper00038172:tax-6null_down_regulated
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00038231:Cry5B_2-fold_downregulated
      WBPaper00040184:hcf-1down_sir-2.1up_daf-2nc
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040963:Q100_up
      WBPaper00040963:Q200_up
      WBPaper00040963:TA300_down
      WBPaper00040985:AIN-2_L4_intestine
      WBPaper00041002:HQ_3d_0.2mM_Down
      WBPaper00041002:HQ_3d_2.0mM_Down
      WBPaper00041174:environmental
      WBPaper00041174:environmental_prime
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041609:hpl-1_hpl-2_downregulated
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00045673:colistin_upregulated
      WBPaper00045960:L1-L4-lethargus_downregulated
      WBPaper00045960:L4-lethargus_downregulated
      WBPaper00047021:MWCNT_upregulated
      WBPaper00048624:hlh-25(ok1710)_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053688:E.faecalis_downregulated
      WBPaper00053688:E.faecium_downregulated
      WBPaper00057098:SiO2-nanoparticles_downregulated
      [cgc5976]:class_2
      [cgc6390]:herm_soma-enriched
    Interaction (45)
  Map_info: Map: V Position: 0.001324 Error: 0.009043
    Positive: Positive_clone: F46E10 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (20)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene