WormBase Tree Display for Gene: WBGene00016061

WBGene00016061 SMap: S_parent: Sequence: C24G6
  Identity: Version: 2
    Name: CGC_name: hpo-15 Paper_evidence: WBPaper00038231
          Person_evidence: WBPerson26
      Sequence_name: C24G6.6
      Molecular_name: C24G6.6
        C24G6.6.1
        CE17462
        C24G6.6.2
        C24G6.6.3
      Other_name: CELE_C24G6.6 Accession_evidence: NDB BX284605
      Public_name: hpo-15
    DB_info: Database: AceView gene 5F990
        WormQTL gene WBGene00016061
        WormFlux gene WBGene00016061
        NDB locus_tag CELE_C24G6.6
        Panther gene CAEEL|WormBase=WBGene00016061|UniProtKB=O76383
          family PTHR10742
        NCBI gene 178934
        RefSeq protein NM_072055.8
        TREEFAM TREEFAM_ID TF318348
        TrEMBL UniProtAcc O76383
        UniProt_GCRP UniProtAcc O76383
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:56 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 26 Apr 2011 13:31:47 WBPerson2970 Name_change: CGC_name: hpo-15
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: hpo
    Allele: WBVar01499528
      WBVar01459949
      WBVar01499740
      WBVar00308214
      WBVar01500129
      WBVar01012604
      WBVar01012605
      WBVar01012606
      WBVar01012607
      WBVar01012608
      WBVar01012609
      WBVar01012610
      WBVar01012611
      WBVar01588263
      WBVar01012612
      WBVar01012613
      WBVar01012614
      WBVar01012615
      WBVar01012616
      WBVar01012617
      WBVar01012618
      WBVar01012619
      WBVar01012620
      WBVar01012621
      WBVar01012622
      WBVar01012623
      WBVar01012624
      WBVar01012625
      WBVar01808010
      WBVar00458587
      WBVar00458588
      WBVar00458589
      WBVar01500006
      WBVar00458590
      WBVar01500007
      WBVar00458591
      WBVar00458592
      WBVar00458593
      WBVar00458594
      WBVar00458595
      WBVar00458596
      WBVar00458597
      WBVar01651591
      WBVar00458598
      WBVar01651592
      WBVar01651593
      WBVar01973499
      WBVar01973500
      WBVar01842335
      WBVar01842336
      WBVar01740250
      WBVar01842337
      WBVar01499496
      WBVar01499316
      WBVar02145187
      WBVar01500066
    RNASeq_FPKM (74)
    GO_annotation: 00038296
      00038297
      00121742
    Ortholog (45)
    Paralog: WBGene00000139 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000137 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000138 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00005010 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00011615 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00019154 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable polyamine oxidase activity. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Is an ortholog of human PAOX (polyamine oxidase) and SMOX (spermine oxidase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:3908 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:20837)
  Molecular_info: Corresponding_CDS: C24G6.6
    Corresponding_transcript: C24G6.6.1
      C24G6.6.2
      C24G6.6.3
    Other_sequence (27)
    Associated_feature: WBsf652630
      WBsf652631
      WBsf652632
      WBsf233684
  Experimental_info: RNAi_result: WBRNAi00091508 Inferred_automatically: RNAi_primary
      WBRNAi00088739 Inferred_automatically: RNAi_primary
      WBRNAi00029153 Inferred_automatically: RNAi_primary
      WBRNAi00011120 Inferred_automatically: RNAi_primary
      WBRNAi00088632 Inferred_automatically: RNAi_primary
      WBRNAi00041103 Inferred_automatically: RNAi_primary
      WBRNAi00085294 Inferred_automatically: RNAi_primary
      WBRNAi00066615 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1020560
      Expr1036862
      Expr1145138
      Expr2012559
      Expr2030796
    Drives_construct: WBCnstr00028352
    Construct_product: WBCnstr00028352
    Microarray_results (23)
    Expression_cluster: WBPaper00030922:glycosylated_protein
      WBPaper00032031:DConiospora_downregulated_OligoArray_24h
      WBPaper00032425:down_in_zfp-1
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00034761:hlh-30_downregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_embryo_enriched
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:intestine_larva_enriched
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00041370:spg-7(RNAi)_upregulated_atfs-1_dependent
      WBPaper00042477:rsr-2(RNAi)_downregulated_RNAseq
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044760:somatic_specific
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045314:S.aureus-induced_hlh-30(tm1978)
      WBPaper00045314:S.aureus-induced_N2
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045934:wrn-1(gk99)_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00047132:skn-1(RNAi)_downregulated
      WBPaper00048657:plep-1(ttTi53821)_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049018:ham-3(RNAi)_downregulated
      WBPaper00049368:daf-2(e1370)_downregulated
      WBPaper00049484:elt-2(RNAi)_downregulated_L4
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049736:15deg-then-25deg(12hr)_upregulated_N2
      WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_downregulated_N2
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049954:BPA_downregulated
      WBPaper00050080:rbr-2(tm3141)_upregulated
      WBPaper00050094:mes-6(bn66)_upregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo
      WBPaper00050332:daf-16(RNAi)_downregulated
      WBPaper00050468:hlh-30-dependent_Cry5B_regulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051039:ash-2(RNAi)_regulated_germline
      WBPaper00051039:intestine_enriched
      WBPaper00051265:F4_hrde-1(tm1200)_upregulated
      WBPaper00051305:vit-2(ac3)_downregulated
      WBPaper00051388:Glucose-diet_downregulated
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00051404:alg-2(ok304)_downregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053154:human-amyloid-beta_tau_regulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053308:NMD(-)_upregulated_SMD-2_non-binding_ClassIII
      WBPaper00053321:mes-2(RNAi)_upregulated_fed-L1_Truseq
      WBPaper00053321:mes-4(RNAi)_upregulated_fed-L1_Truseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053798:nhr-49(nr2041)_tBOOH_upregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00053814:25C_upregulated_OP50
      WBPaper00053814:OP50_vs_PY79_downregulated_PY79
      WBPaper00054758:alg-1(gk204)_downregulated
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055482:Tunicamycin_upregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056139:gut-microbiota_upregulated
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056443:DietaryRestriction_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056826:hmc_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058691:set-2(bn129)_downregulated
      WBPaper00058711:paraquat_downregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059253:sucrose_downregulated
      WBPaper00059253:sucrose_stearic-acid_downregulated
      WBPaper00059604:fluvastatin_upregulated_dlk-1(km12)
      WBPaper00059604:fluvastatin_upregulated_N2
      WBPaper00059735:glucose_downregulated_lpin-1(RNAi)
      WBPaper00059735:glucose_downregulated_N2
      WBPaper00059739:hira-1(gk835598)_downregulated_adult
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059987:Wounding_downregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_lin-40(yth27)
      WBPaper00060273:isp-1(qm150)_downregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_N2
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060683:hlh-11(overexpression)_downregulated
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061007:M.braciatum_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061045:Y56A3A.22(cck200)_upregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061274:hypergravity_10xg_downregulated
      WBPaper00061274:hypergravity_15xg_downregulated
      WBPaper00061340:Intestine
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061527:F35C8.5-T10B5.7
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00061800:miR-85(n4117)_downregulated_20C
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062197:mec-8_upregulated_TRN
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00062440:crh-1(syb385)_downregulated
      WBPaper00062456:doxycycline_downregulated_CB4856_protein
      WBPaper00064005:starvation_upregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064315:mes-3(bn199)_upregulated_EGCs
      WBPaper00064315:mes-3(bn199)_upregulated_PGCs
      WBPaper00064315:mes-4(bn73)_upregulated_EGCs
      WBPaper00064315:mes-4(bn73)_upregulated_PGCs
      WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064871:hypoxia_downregulated_F3
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065086:JU1400_N.ausubeli_regulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065086:JU1400_N.ironsii_regulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065749:endu-2(tm4977)_upregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
      WBPaper00065841:18_0
      WBPaper00065841:78_0
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00065995:M.humicola-extract_upregulated_N2
      WBPaper00066085:sin-3(syb2172)_upregulated
      WBPaper00066085:sin-3(tm1276)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      cgc4386_cluster_1_1
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00027111:rrf-1(pk1417)_upregulated
      WBPaper00032062:age_regulated_genes
      WBPaper00032165:differentially_expressed_with_age_medoid_4
      WBPaper00032948:StarveUp3
      WBPaper00033101:spr-5_regulated
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035227:heat_shock_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-11_regulated
      WBPaper00035873:osmotically_regulated
      WBPaper00036286:Pattern_I
      WBPaper00037695:LD_3-day
      WBPaper00037695:WC_5-day
      WBPaper00038172:crh-1null_down_regulated
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040876:mir-35_downregulated
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:environmental_prime
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042128:gei-8(ok1671)_upregulated
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00045960:L1-L4-lethargus_downregulated
      WBPaper00045960:L4-lethargus_downregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00055899:nitroguanidine_regulated
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc5976]:class_2
      [cgc6390]:herm_soma-enriched
    Interaction (138)
  Map_info: Map: V Position: -1.74087 Error: 0.007229
    Positive: Positive_clone: C24G6 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00030371
    WBPaper00038491
    WBPaper00055090
    WBPaper00065331
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene