pqn-60 encodes a 154-residue, glutamine/asparagine (Q/N)-rich('prion'-like) protein, predicted to have coiled-coil structure, withmany paralogs in nematodes but no obvious non-nematode orthologs; PQN-60inhibits CEP-1- and HUS-1-dependent germline apoptosis, as do BMK-1,RAD-50, and RAD-51.
Enriched in ABaraapapaa; ABaraapppaa; arcade cell; and pharynx based on microarray and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and tiling array studies. Is affected by twenty chemicals including methylmercuric chloride; Mercuric Chloride; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: SXP/RAL-2 family protein Ani s 5-like, metal-binding domain and SXP/RAL-2 family protein Ani s 5-like, cation-binding domain.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.