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WormBase Tree Display for Gene: WBGene00004076

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Name Class

WBGene00004076SMapS_parentSequenceW09B6
IdentityVersion2
NameCGC_namepod-2Person_evidenceWBPerson26
Sequence_nameW09B6.1
Molecular_name (12)
Other_namephi-47Person_evidenceWBPerson2582
CELE_W09B6.1Accession_evidenceNDBBX284602
Public_namepod-2
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:34WBPerson1971EventImportedInitial conversion from geneace
219 Aug 2005 11:54:06WBPerson2970EventAcquires_mergeWBGene00021102
Acquires_mergeWBGene00021102
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpod
Allele (335)
Possibly_affected_byWBVar02153249
StrainWBStrain00008572
WBStrain00049317
WBStrain00054654
WBStrain00054709
RNASeq_FPKM (74)
GO_annotation (25)
Ortholog (46)
ParalogWBGene00012131Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004258Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00009319Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00017864Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionpod-2 encodes an acetyl-CoA carboxylase; by sequence similarity, POD-2 is predicted to catalyze the first step in de novo fatty acid biosynthesis; pod-2 is required for proper embryonic polarity and for osmotic protection of the eggshell; pod-2 activity is also required for molting.Paper_evidenceWBPaper00004706
WBPaper00005095
WBPaper00024324
WBPaper00026763
Curator_confirmedWBPerson1843
Date_last_updated14 Oct 2008 00:00:00
Automated_descriptionPredicted to enable acetyl-CoA carboxylase activity. Involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; nematode larval development; and polarity specification of anterior/posterior axis. Predicted to be located in endoplasmic reticulum membrane and mitochondrion. Expressed in CANL; CANR; and excretory duct. Used to study muscular disease. Is an ortholog of human ACACA (acetyl-CoA carboxylase alpha).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:0080000Homo sapiensPaper_evidenceWBPaper00061805
Curator_confirmedWBPerson324
Date_last_updated25 Apr 2022 00:00:00
Models_disease_in_annotationWBDOannot00001162
Molecular_infoCorresponding_CDSW09B6.1a
W09B6.1b
W09B6.1c
Corresponding_transcriptW09B6.1a.1
W09B6.1a.2
W09B6.1a.3
W09B6.1a.4
W09B6.1b.1
W09B6.1c.1
Other_sequence (71)
Associated_feature (18)
Experimental_infoRNAi_resultWBRNAi00036389Inferred_automaticallyRNAi_primary
WBRNAi00092933Inferred_automaticallyRNAi_primary
WBRNAi00065024Inferred_automaticallyRNAi_primary
WBRNAi00090854Inferred_automaticallyRNAi_primary
WBRNAi00095760Inferred_automaticallyRNAi_primary
WBRNAi00082111Inferred_automaticallyRNAi_primary
WBRNAi00082106Inferred_automaticallyRNAi_primary
WBRNAi00092271Inferred_automaticallyRNAi_primary
WBRNAi00094284Inferred_automaticallyRNAi_primary
WBRNAi00019738Inferred_automaticallyRNAi_primary
WBRNAi00102781Inferred_automaticallyRNAi_primary
WBRNAi00094188Inferred_automaticallyRNAi_primary
WBRNAi00026520Inferred_automaticallyRNAi_primary
WBRNAi00055011Inferred_automaticallyRNAi_primary
WBRNAi00086007Inferred_automaticallyRNAi_primary
WBRNAi00009271Inferred_automaticallyRNAi_primary
WBRNAi00095246Inferred_automaticallyRNAi_primary
WBRNAi00066819Inferred_automaticallyRNAi_primary
WBRNAi00092272Inferred_automaticallyRNAi_primary
WBRNAi00102657Inferred_automaticallyRNAi_primary
WBRNAi00086006Inferred_automaticallyRNAi_primary
WBRNAi00111754Inferred_automaticallyRNAi_primary
WBRNAi00085992Inferred_automaticallyRNAi_primary
WBRNAi00095247Inferred_automaticallyRNAi_primary
Expr_patternChronogram1203
Expr6859
Expr9289
Expr12921
Expr15196
Expr1021344
Expr1031965
Expr1158544
Expr2014988
Expr2033223
Drives_constructWBCnstr00003313
WBCnstr00013878
WBCnstr00023095
Regulate_expr_clusterWBPaper00038215:pod-2(RNAi)_regulated
Microarray_results (29)
Expression_clusterWBPaper00032528:L3_enriched
WBPaper00036375:enriched_in_PVD_OLL
WBPaper00037086:biotin_regulated
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00038118:aak-2(gt33)_upregulated
WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
WBPaper00040412:germline-regulated_daf-16_target
WBPaper00044426:rotenone_24h_downregulated
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044736:oscillating_dev_expression
WBPaper00044746:aging_downregulated_Day5
WBPaper00044746:aging_downregulated_HeatShock
WBPaper00045420:fertilization_downregulated_transcript
WBPaper00045521:Gender_Neutral
WBPaper00045571:germline-ablation_upregulated
WBPaper00045934:wrn-1(gk99)_upregulated
WBPaper00046012:tdp-1(ok803)_downregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00046497:B.thuringiensis_downregulated_protein
WBPaper00046691:P1_enriched
WBPaper00046795:starvation_downregulated
WBPaper00048988:neuron_expressed
WBPaper00049217:DAF-16_upregulated
WBPaper00049545:cco-1(RNAi)_upregulated
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
WBPaper00049905:Age_variant_expression
WBPaper00050182:lmn-1(L535P)_downregulated
WBPaper00050412:cco-1(RNAi)_upregulated_N2
WBPaper00050698:DEP-1_interacting
WBPaper00050726:starvation_regulated_LowSalt
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:body-muscle_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00050990:seam_expressed
WBPaper00051039:intestine_enriched
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00052987:UV_downregulated_xpc-1;csb-1
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053321:embryo-to-L1_upregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
WBPaper00053388:dauer_regulated_Cluster1
WBPaper00053814:15C_downregulated_OP50
WBPaper00053814:15C_downregulated_PY79
WBPaper00055049:S.gordonii_downregulated
WBPaper00055060:flr-1(RNAi)_upregulated
WBPaper00055334:DLC-1_interacting
WBPaper00055354:Rapamycin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
WBPaper00055354:Rapamycin-Rifampicin_upregulated
WBPaper00055354:Rifampicin-Psora_upregulated
WBPaper00055482:pmt-2(RNAi)_upregulated
WBPaper00055482:Tunicamycin_downregulated
WBPaper00055827:daf-2(e1370)_downregulated
WBPaper00055827:pfd-6(gk493446)_downregulated
WBPaper00055971:nhl-2(ok818)_20C_downregulated
WBPaper00055981:fog-2(q71)_downregulated
WBPaper00056034:pals-22(jy3)_upregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_upregulated_N2
WBPaper00056275:P.aeruginosa_downregulated
WBPaper00056275:P.aeruginosa_downregulated_pmk-1(km25)_dependent
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056809:smn-1(ok355)_downregulated
WBPaper00056826:hmc_biased
WBPaper00057154:HeatShock_downregulated_mRNA
WBPaper00057154:HeatShock_upregulated_miRNA-target
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058725:sftb-1(cer6)_downregulated
WBPaper00058725:sftb-1(cer39)_downregulated
WBPaper00058958:100mGy-irradiation-72h_upregulated
WBPaper00059254:CSR-1_interacting
WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
WBPaper00059334:sacy-1(depletion)_regulated
WBPaper00059471:EGL-43_interacting
WBPaper00059605:MUT-16_interacting
WBPaper00059824:rnp-6(dh1127)_regulated_OP50
WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
WBPaper00060100:SiNP_upregulated_mRNA
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060683:hlh-11(ko1)_downregulated
WBPaper00060871:M.humicola-infection_48h_regulated
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
WBPaper00061203:let-418(n3536)_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:G2_and_W_blasts
WBPaper00061340:hyp7_AB_lineage
WBPaper00061340:P_cell
WBPaper00061340:T
WBPaper00061439:unc-30(ok613)_upregulated
WBPaper00061478:SUMO-conjugated_protein
WBPaper00061527:dld-1-skn-1_16701
WBPaper00061572:oleic-acid-specific_mating_downregulated
WBPaper00061651:Gonadal_sheath_cell_enriched
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062345:bortezomib_4h_downregulated_N2
WBPaper00062345:bortezomib_4h_downregulated_zip-1(jy13)
WBPaper00062456:doxycycline_upregulated_CB4856_protein
WBPaper00062498:PPM-1.D_interacting
WBPaper00062554:MAGU-2_interacting
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064005:starvation_upregulated_N2_protein
WBPaper00064055:trl-1(cas1077)_upregulated_non-starved
WBPaper00064055:trl-1(cas1077)_upregulated_starved
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
WBPaper00064315:mes-3(bn199)_downregulated_PGCs
WBPaper00064539:nhr-114(gk849)_upregulated
WBPaper00064637:cox-5B(RNAi)_upregulated
WBPaper00065086:JU1400_N.ausubeli_regulated
WBPaper00065086:JU1400_N.ferruginous_regulated
WBPaper00065086:N2_N.ausubeli_regulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065373:Cisplatin_downregulated_WT
WBPaper00065373:sek-1(km4)_downregulated_cisplatin
WBPaper00065373:sek-1(km4)_downregulated_Ref
WBPaper00065746:eat-2(ad1113)_upregulated
WBPaper00065841:69_0
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066038:mip-1(how5)_upregulated
cgc4386_cluster_1_1
WBPaper00027342:alpha-Synuclein(A53T)_downregulated
WBPaper00031003:hlh_1_enriched
WBPaper00031832:slr-2_regulated
WBPaper00032948:StarveUp3
WBPaper00035227:heat_shock_regulated
WBPaper00036123:Cadmium_regulated
WBPaper00036286:Pattern_C
WBPaper00037695:DD_3-day
WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
WBPaper00040821:Au-NP_regulated
WBPaper00040858:eQTL_regulated_reproductive
WBPaper00041002:HF_11d_0.2mM_Up
WBPaper00041174:environmental
WBPaper00041174:genotypic
WBPaper00041174:genotypic_and_environmental
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00045673:colistin_upregulated
WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
WBPaper00048989:N2_allantoin_downregulated
WBPaper00050650:mBmkTX_downregulated
[cgc5767]:expression_class_E
[cgc5767]:expression_class_E_pi(143_min)
[cgc5767]:expression_class_M
[cgc5767]:expression_class_ME
Interaction (107)
Map_infoMapIIPosition-15.5649
PositivePositive_cloneW09B6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5516
4672
Pseudo_map_position
Reference (45)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene