WormBase Tree Display for Gene: WBGene00001244

WBGene00001244 SMap: S_parent: Sequence: F41H10
  Identity: Version: 1
    Name: CGC_name: elo-6 Person_evidence: WBPerson79
      Sequence_name: F41H10.8
      Molecular_name: F41H10.8
        F41H10.8.1
        CE10286
      Other_name: CELE_F41H10.8 Accession_evidence: NDB BX284604
      Public_name: elo-6
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:23 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: elo
    Allele (29)
    Strain: WBStrain00033919
      WBStrain00035760
    RNASeq_FPKM (74)
    GO_annotation (19)
    Ortholog (50)
    Paralog: WBGene00001239 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001240 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001241 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001242 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001243 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001247 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001245 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00001246 Caenorhabditis elegans From_analysis: Panther
    Structured_description: Concise_description: The elo-6 gene encodes a paralog of elo-1 and elo-2, each of which encodes a polyunsaturated fatty acid (PUFA) elongase; ELO-6 may be required for a normally high growth rate. Paper_evidence: WBPaper00004162
            WBPaper00005654
            WBPaper00005728
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable fatty acid elongase activity. Involved in methyl-branched fatty acid biosynthetic process. Predicted to be located in membrane. Expressed in amphid neurons; intestine; nerve ring; and vulva. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F41H10.8
    Corresponding_transcript: F41H10.8.1
    Other_sequence (98)
    Associated_feature: WBsf651798
      WBsf651799
      WBsf996493
      WBsf1017377
      WBsf230083
  Experimental_info: RNAi_result (13)
    Expr_pattern: Chronogram341
      Expr3073
      Expr3791
      Expr1014772
      Expr1030789
      Expr1150912
      Expr2011283
      Expr2029519
    Drives_construct: WBCnstr00001070
      WBCnstr00011115
      WBCnstr00011662
      WBCnstr00037015
    Construct_product: WBCnstr00011115
      WBCnstr00037015
    Microarray_results (18)
    Expression_cluster: WBPaper00005700:transmembrane_protein
      WBPaper00024505:pharyngeal_enriched
      WBPaper00028802:intestine_unique
      WBPaper00029359_1217
      WBPaper00029359_1280
      WBPaper00029359_1353
      WBPaper00029359_1444
      WBPaper00029359_1504
      WBPaper00029359_1548
      WBPaper00029359_1604
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032528:L3_enriched
      WBPaper00035269:cde-1_regulated
      WBPaper00037086:biotin_regulated
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:pharyngeal-muscle_embryo_enriched
      WBPaper00037950:pharyngeal-muscle_embryo_SelectivelyEnriched
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_larva_enriched
      WBPaper00037950:PVD-OLL-neurons_larva_SelectivelyEnriched
      WBPaper00038104:DATS_upregulated
      WBPaper00038168:lin-35_downregulated
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040209:B.thuringiensis_downregulated_MY15
      WBPaper00040209:B.thuringiensis_downregulated_MY18
      WBPaper00040990:PA14_downregulated
      WBPaper00041370:spg-7(RNAi)_upregulated_atfs-1_dependent
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044316:HgCl2_7.5uM_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00045390:ubc-9(RNAi)_upregulated
      WBPaper00045401:N.parisii_40h_downregulated
      WBPaper00045401:N.parisii_64h_downregulated
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00046121:mesoderm_unique
      WBPaper00046128:ethanol_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046741:Garlic-Extract_upregulated_mRNA
      WBPaper00046795:starvation_downregulated
      WBPaper00047132:skn-1(RNAi)_downregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049018:swsn-2.2(RNAi)_upregulated
      WBPaper00049217:DAF-16_upregulated
      WBPaper00049498:npr-1(ur89)_regulated_8
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049905:Age_variant_expression
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050096:P.aeruginosa_downregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo
      WBPaper00050193:met-2(n4256)set-25(n5021)_downregulated_L1
      WBPaper00050332:daf-16(RNAi)_downregulated
      WBPaper00050332:skn-1(RNAi)_downregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_specific
      WBPaper00051305:vit-2(ac3)_downregulated
      WBPaper00051371:Orsay-virus-infection_downregulated_rde-1(ne219)
      WBPaper00051558:aging_regulated
      WBPaper00052856:Cadmium_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00052987:UV_downregulated_xpc-1;csb-1
      WBPaper00053092:procyanidins_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00054192:cold-shock_downregulated
      WBPaper00055049:S.gordonii_downregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_downregulated
      WBPaper00055971:nhl-2(ok818)_20C_downregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay4
      WBPaper00056617:adr-1(tm668)_downregulated_L4_protein
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057265:metaformin_upregulated_OP50
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00059117:B.subtilis_downregulated
      WBPaper00059191:hsp-16.2p-LIN-29_downregulated
      WBPaper00059253:stearic-acid_upregulated
      WBPaper00059253:sucrose_stearic-acid_upregulated
      WBPaper00059253:sucrose_upregulated
      WBPaper00059537:ngn-1(ok2200)_downregulated
      WBPaper00059739:hira-1(gk835598)_downregulated_adult
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059895:wounding_downregulated
      WBPaper00059987:Wounding_downregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060014:set-2(zr2012)_downregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:CoCl2_6hr_downregulated_N2
      WBPaper00060399:pqm-1(ok485)_downregulated_CoCl2_6hr
      WBPaper00060445:nfki-1(cer1)_upregulated_L1
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060683:hlh-11(overexpression)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060871:M.humicola-extract_24h_regulated
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:Anterior_arcade_cell
      WBPaper00061340:I2_grandparent
      WBPaper00061340:mc1
      WBPaper00061340:mc2
      WBPaper00061340:Parent_of_g1P_I3
      WBPaper00061340:Pharyngeal_marginal_cell
      WBPaper00061340:Pharyngeal_neuron
      WBPaper00061340:pm1_pm2
      WBPaper00061340:pm3_pm4_pm5
      WBPaper00061340:Posterior_arcade_cell
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061479:ubc-9(ne4833)_upregulated
      WBPaper00061527:R10H10.3-T21H3.1
      WBPaper00061530:nhr-49(e2144)_downregulated
      WBPaper00062056:lin-36(we31)_downregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_downregulated_N2
      WBPaper00062345:bortezomib_4h_downregulated_zip-1(jy13)
      WBPaper00062518:atf-4_regulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00063930:BRD-1_interacting
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064055:trl-1(cas1077)_downregulated_non-starved
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064107:lin-35(n745)_downregulated
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064315:mes-4(bn73)_upregulated_EGCs
      WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00064632:daf-2(e1370)_upregulated_intestine
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064728:cpl-1(W32AY35A)_upregulated
      WBPaper00064789:Day6_vs_Day1_downregulated_neuron
      WBPaper00064789:Day9_vs_Day1_downregulated_neuron
      WBPaper00064789:Day12_vs_Day1_downregulated_neuron
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065086:JU1400_N.ausubeli_regulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065086:JU1400_N.ironsii_regulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:AFD_depleted
      WBPaper00065225:nhr-42(tm1375)_downregulated_S.aureus-infected
      WBPaper00065258:anchor-cell_depleted
      WBPaper00065749:Heat-Shock-With-Recovery_downregulated_N2
      WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
      WBPaper00065841:3_5
      WBPaper00065841:9_0
      WBPaper00065841:9_1
      WBPaper00065841:9_2
      WBPaper00065841:15_0
      WBPaper00065841:24_0
      WBPaper00065841:24_1
      WBPaper00065841:27_0
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00065995:M.humicola-extract_upregulated_N2
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      WBPaper00066232:hsf-1(RNAi)_downregulated_WT
      cgc4386_cluster_1_5
      cgc4489_group_2
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00027342:alpha-Synuclein(WT)_upregulated
      WBPaper00028482:PA14_downregulated
      WBPaper00028789:PA14_vs_gacA_downregulated_4hr
      WBPaper00028789:PA14_vs_gacA_downregulated_8hr
      WBPaper00028789:PA14_vs_OP50_downregulated_4hr
      WBPaper00028789:PA14_vs_OP50_downregulated_8hr
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031060:2-deoxy-D-glucose_downregulated
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00032062:age_regulated_genes
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00036286:Pattern_C
      WBPaper00036375:depleted_in_PVD_OLL
      WBPaper00036464:S.aureus-RN6390_regulated
      WBPaper00037695:WC_5-day
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00038231:Cry5B_2-fold_downregulated
      WBPaper00040426:CYD-1_CDK-4_downregulated
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040963:Q50_up
      WBPaper00040985:AIN-2_asynchronous_intestine
      WBPaper00040985:AIN-2_L4_intestine
      WBPaper00041174:environmental
      WBPaper00041174:environmental_prime
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00044091:Bpseudomallei_repressed_2h
      WBPaper00044091:Bpseudomallei_repressed_4h
      WBPaper00044091:Bpseudomallei_repressed_8h
      WBPaper00044091:Bpseudomallei_repressed_12h
      WBPaper00045673:colistin_upregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00048624:hlh-25(ok1710)_upregulated
      WBPaper00053236:daf-16(mgDF50)_regulated_Starved
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00057098:SiO2-nanoparticles_downregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
    Interaction (196)
  Map_info: Map: IV Position: 1.63242 Error: 0.003547
    Positive: Positive_clone: F41H10 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4281
        4282
        4423
    Pseudo_map_position
  Reference (13)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene