WormBase Tree Display for Gene: WBGene00001240
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| WBGene00001240 | SMap | S_parent | Sequence | F11E6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | elo-2 | Person_evidence | WBPerson79 | |||||
| Sequence_name | F11E6.5 | ||||||||
| Molecular_name | F11E6.5 | ||||||||
| F11E6.5.1 | |||||||||
| CE19785 | |||||||||
| Other_name | CELE_F11E6.5 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | elo-2 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | elo | ||||||||
| Allele (25) | |||||||||
| Strain | WBStrain00049341 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Ortholog (55) | |||||||||
| Paralog | WBGene00001239 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00001247 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00001242 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00001245 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00001244 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00001243 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00001246 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00001241 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | elo-2 encodes a palmitic acid elongase, homologous to polyunsaturated fatty acid (PUFA) elongases such as ELO-1, that is required for normally rapid growth, normally large body size, fertility, and for the quantitative regulation of the ultradian defecation rhythm; the joint action of ELO-2 with ELO-1 is strongly required for 20-carbon PUFA production and for general viability; loss of el-2 activity via RNAi also results in decreased intestinal dipeptide transport and increased fat droplet size; elo-2 is most strongly expressed in intestinal cells, as well as other tissues such as the ventral nerve cord, pharyngeal muscles, uterus, and tail. | Paper_evidence | WBPaper00004162 | |||||
| WBPaper00005654 | |||||||||
| WBPaper00005728 | |||||||||
| WBPaper00040287 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable fatty acid elongase activity. Involved in several processes, including determination of adult lifespan; lipid metabolic process; and regulation of gene expression. Predicted to be located in membrane. Expressed in intestine; pharyngeal muscle cell; tail; uterus; and ventral nerve cord. Is an ortholog of human ELOVL3 (ELOVL fatty acid elongase 3) and ELOVL6 (ELOVL fatty acid elongase 6). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F11E6.5 | |||||||
| Corresponding_transcript | F11E6.5.1 | ||||||||
| Other_sequence (67) | |||||||||
| Associated_feature | WBsf652427 | ||||||||
| WBsf655542 | |||||||||
| WBsf978977 | |||||||||
| WBsf999043 | |||||||||
| Experimental_info | RNAi_result (30) | ||||||||
| Expr_pattern | Expr2433 | ||||||||
| Expr1028402 | |||||||||
| Expr1030786 | |||||||||
| Expr1148341 | |||||||||
| Expr2011279 | |||||||||
| Expr2029515 | |||||||||
| Drives_construct | WBCnstr00010825 | ||||||||
| WBCnstr00015807 | |||||||||
| WBCnstr00015808 | |||||||||
| WBCnstr00037019 | |||||||||
| Construct_product | WBCnstr00010825 | ||||||||
| WBCnstr00037019 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (228) | |||||||||
| Interaction (41) | |||||||||
| Map_info | Map | IV | Position | 17.1016 | Error | 0.029226 | |||
| Positive | Positive_clone | F11E6 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4901 | |||||||
| 4433 | |||||||||
| 4778 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (31) | |||||||||
| Picture | WBPicture0000013096 | ||||||||
| Remark | elo-2 was previously incorrectly connected to C40H1.4 [021023 ck1] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
