nsy-4 encodes a member of the PMP22/EMP/claudin/calcium channel gamma subunit family; nsy-4 is worm-specific, with obvious homologs only in C. elegans; nsy-4 functions with nsy-5 to induce the AWC chemosensory neuron ON fate by regulating the activity of the UNC-2/UNC-36 calcium channel.
Enables calcium channel inhibitor activity and protein kinase inhibitor activity. Involved in determination of left/right asymmetry in nervous system. Located in plasma membrane and plasma membrane bounded cell projection. Expressed in anterior hypodermis; blast cell; excretory cell; neurons; and tail hypodermis.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.