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WormBase Tree Display for Gene: WBGene00016067

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Name Class

WBGene00016067SMapS_parentSequenceC24H10
IdentityVersion2
NameCGC_nameclc-7Person_evidenceWBPerson260
Sequence_nameC24H10.1
Molecular_nameC24H10.1a
C24H10.1a.1
CE39564
C24H10.1b
CE54322
C24H10.1b.1
Other_nameCELE_C24H10.1Accession_evidenceNDBBX284606
Public_nameclc-7
DB_infoDatabaseAceViewgeneXF689
WormQTLgeneWBGene00016067
WormFluxgeneWBGene00016067
NDBlocus_tagCELE_C24H10.1
PanthergeneCAEEL|WormBase=WBGene00016067|UniProtKB=Q18135
familyPTHR35574
NCBIgene182855
RefSeqproteinNM_001395348.1
NM_001383572.2
TrEMBLUniProtAccQ18135
A0A8D8EJW4
UniProt_GCRPUniProtAccA0A8D8EJW4
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:56WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
219 Apr 2021 01:27:01WBPerson1983Name_changeCGC_nameclc-7
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classclc
Allele (109)
RNASeq_FPKM (74)
GO_annotation00060267
00121753
Ortholog (29)
ParalogWBGene00000523Caenorhabditis elegansFrom_analysisTreeFam
WBGene00000526Caenorhabditis elegansFrom_analysisTreeFam
WBGene00010742Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
WBGene00011014Caenorhabditis elegansFrom_analysisTreeFam
Panther
WBGene00013458Caenorhabditis elegansFrom_analysisPanther
WBGene00021415Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionC24H10.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; C24H10.1 is worm-specific, with obvious homologs only in C. elegans; C24H10.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.Paper_evidenceWBPaper00004961
WBPaper00005654
WBPaper00005946
WBPaper00005975
WBPaper00012856
WBPaper00018356
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to be located in membrane.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC24H10.1a
C24H10.1b
Corresponding_CDS_historyC24H10.1:wp153
Corresponding_transcriptC24H10.1a.1
C24H10.1b.1
Other_sequence (24)
Associated_featureWBsf648073
WBsf1005170
WBsf235669
WBsf235670
Experimental_infoRNAi_resultWBRNAi00011122Inferred_automaticallyRNAi_primary
WBRNAi00041111Inferred_automaticallyRNAi_primary
Expr_patternExpr1026641
Expr1145144
Expr2001047
Expr2019265
Drives_constructWBCnstr00028347
Construct_productWBCnstr00028347
Microarray_results (19)
Expression_cluster (125)
InteractionWBInteraction000359963
Map_infoPositivePositive_cloneC24H10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionX-6.19645
ReferenceWBPaper00065267
MethodGene