Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00010742

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00010742SMapS_parentSequenceK10D6
IdentityVersion2
NameCGC_nameclc-6Person_evidenceWBPerson260
Sequence_nameK10D6.2
Molecular_name (16)
Other_nameCELE_K10D6.2Accession_evidenceNDBBX284605
Public_nameclc-6
DB_infoDatabaseAceViewgene5L674
WormQTLgeneWBGene00010742
WormFluxgeneWBGene00010742
NDBlocus_tagCELE_K10D6.2
PanthergeneCAEEL|WormBase=WBGene00010742|UniProtKB=O45669
familyPTHR10671
NCBIgene179548
RefSeqproteinNM_073442.4
NM_001383401.1
NM_001373109.3
NM_001380762.2
TREEFAMTREEFAM_IDTF316179
TrEMBLUniProtAccE9P878
O45669
O45670
Q9NAP4
UniProt_GCRPUniProtAccO45669
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
219 Apr 2021 01:27:01WBPerson1983Name_changeCGC_nameclc-6
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classclc
Allele (33)
StrainWBStrain00037210
RNASeq_FPKM (74)
GO_annotation00008356
00008357
00117860
Ortholog (29)
ParalogWBGene00000522Caenorhabditis elegansFrom_analysisPanther
WBGene00000523Caenorhabditis elegansFrom_analysisTreeFam
Panther
WBGene00000526Caenorhabditis elegansFrom_analysisTreeFam
Panther
WBGene00021415Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00011014Caenorhabditis elegansFrom_analysisTreeFam
WBGene00016706Caenorhabditis elegansFrom_analysisPanther
WBGene00016067Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
Structured_descriptionConcise_descriptionK10D6.2 encodes three isoforms of a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; K10D6.2A-C are worm-specific, with obvious homologs only in C. elegans; K10D6.2A-C are required for embryonic viability in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.Paper_evidenceWBPaper00004651
WBPaper00004961
WBPaper00005946
WBPaper00005975
WBPaper00012856
WBPaper00018356
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to be located in plasma membrane. Expressed in ciliated neurons and hypodermis.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS290 version of WormBase
Date_last_updated11 Sep 2023 00:00:00
Molecular_infoCorresponding_CDSK10D6.2a
K10D6.2b
K10D6.2c
K10D6.2d
Corresponding_CDS_historyK10D6.2a:wp227
K10D6.2c:wp114
K10D6.2d:wp227
Corresponding_transcriptK10D6.2a.1
K10D6.2b.1
K10D6.2b.2
K10D6.2c.1
K10D6.2c.2
K10D6.2c.3
K10D6.2c.4
K10D6.2d.1
Other_sequence (36)
Associated_feature (14)
Experimental_infoRNAi_resultWBRNAi00050542Inferred_automaticallyRNAi_primary
WBRNAi00034262Inferred_automaticallyRNAi_primary
WBRNAi00001132Inferred_automaticallyRNAi_primary
Expr_patternExpr3179
Expr1025973
Expr1034703
Expr1154247
Expr2005037
Expr2023256
Drives_constructWBCnstr00011199
WBCnstr00031180
Construct_productWBCnstr00011199
WBCnstr00031180
Microarray_results (34)
Expression_cluster (218)
InteractionWBInteraction000551579
WBInteraction000581956
Map_infoMapVPosition2.97044
PositivePositive_cloneK10D6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene