Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in PERK-mediated unfolded protein response. Predicted to be located in cytoplasm and microtubule. Expressed in pharynx. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 1 and congenital fibrosis of the extraocular muscles 3A. Is an ortholog of several human genes including TUBB3 (tubulin beta 3 class III); TUBB6 (tubulin beta 6 class V); and TUBB8B (tubulin beta 8B).
Sequence connection from [Gogonea CB, Siddiqui SS]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.