WormBase Tree Display for Expression_cluster: WBPaper00045257:bar-1(ga80)_upregulated
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| WBPaper00045257:bar-1(ga80)_upregulated | Description | Genes that showed increased expression in bar-1(ga80) animal comparing to in N2. | |
|---|---|---|---|
| Species | Caenorhabditis elegans | ||
| Algorithm | All statistical analyses were performed using the statistical programming language R (version 2.13.1 x 64). A linear model was used to determine the effect and significance of the genotype on the expression levels (probe intensity + genotype + error). Using permutations of the original data in the same linear model, authors determined thresholds adjusted for multiple testing (FDR 0.05: -log10(p) > 2; FDR 0.01: -log10(p) > 3). To correct for the developmental difference between bar-1(ga80) and N2 authors used the developmental gene expression data from Snoek et al. (2014) together with the gene expression data generated for this study (bar-1(ga80) vs. N2) in one linear model (probe intensity, sample age + genotype + error). The intensities were corrected for batch effect and for sample age authors used an age of 44 hours for the bar-1(ga80) samples (as estimated), and 48 hours for the N2 samples. | ||
| Reference | WBPaper00045257 | ||
| Based_on_WB_Release | 220 | ||
| Gene (416) | |||
| Attribute_of | Microarray_experiment | ||
| Regulation | Regulated_by_gene | WBGene00000238 | |
| Associated_with | Life_stage | WBls:0000038 |
