WormBase Tree Display for Gene: WBGene00007680

WBGene00007680 SMap: S_parent: Sequence: C18D11
  Identity: Version: 2
    Name: CGC_name: maa-1
      Sequence_name: C18D11.2
      Molecular_name: C18D11.2
        C18D11.2.1
        CE18513
      Other_name: CELE_C18D11.2 Accession_evidence: NDB BX284603
      Public_name: maa-1
    DB_info: Database: AceView gene 3M910
        WormQTL gene WBGene00007680
        WormFlux gene WBGene00007680
        NDB locus_tag CELE_C18D11.2
        Panther gene CAEEL|WormBase=WBGene00007680|UniProtKB=Q9XTZ5
          family PTHR23310
        NCBI gene 176612
        RefSeq protein NM_067130.6
        TREEFAM TREEFAM_ID TF319446
        TrEMBL UniProtAcc Q9XTZ5
        UniProt_GCRP UniProtAcc Q9XTZ5
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:48 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 02 Jul 2004 16:55:44 WBPerson1971 Name_change: CGC_name: maa-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: maa
    Allele (57)
    Strain: WBStrain00032337
      WBStrain00035474
    RNASeq_FPKM (74)
    GO_annotation (17)
    Ortholog (38)
    Paralog: WBGene00001153 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00016655 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00044603 Caenorhabditis elegans From_analysis: Panther
      WBGene00018949 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00009818 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00012457 Caenorhabditis elegans From_analysis: Panther
    Structured_description: Concise_description: maa-1 encodes a novel, transmembrane acyl-CoA-binding protein; maa-1 activity, together with that of rme-1, is required for normal rates of endosomal recycling and for proper endosomal shape and morphology; a rescuing MAA-1::GFP fusion protein is expressed in the hypodermis (excluding the seam cells) and the intestine, as well as in an area near the dorsal and ventral nerve cords; within the hypodermis and intestine, MAA-1::GFP localizes to endosomal and Golgi vesicle membranes. Paper_evidence: WBPaper00028338
          Curator_confirmed: WBPerson1843
          Date_last_updated: 20 Feb 2008 00:00:00
      Automated_description: Enables fatty-acyl-CoA binding activity. Involved in endocytic recycling; endosome organization; and multicellular organism reproduction. Located in apical part of cell; basal part of cell; and bounding membrane of organelle. Expressed in hypodermis. Is an ortholog of human ACBD4 (acyl-CoA binding domain containing 4). Paper_evidence: WBPaper00065943
          Curator_confirmed (2)
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C18D11.2
    Corresponding_transcript: C18D11.2.1
    Other_sequence: CRC10935_1
      CBC05789_1
      CJC13489_1
      ACC00514_1
      CR04599
    Associated_feature: WBsf651519
      WBsf227602
  Experimental_info: RNAi_result: WBRNAi00010998 Inferred_automatically: RNAi_primary
      WBRNAi00006289 Inferred_automatically: RNAi_primary
      WBRNAi00029068 Inferred_automatically: RNAi_primary
      WBRNAi00040923 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr8267
      Expr1028301
      Expr1033316
      Expr1144969
      Expr2013321
      Expr2031553
    Drives_construct: WBCnstr00013222
    Construct_product: WBCnstr00013222
    Microarray_results (19)
    Expression_cluster: WBPaper00031040:Cluster_5
      WBPaper00032425:down_in_rde-4
      WBPaper00032425:down_in_zfp-1
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_embryo_enriched
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00044736:flat_dev_expression
      WBPaper00045521:Spermatogenic
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045861:set-2(ok952)_upregulated
      WBPaper00046121:endoderm_unique
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048988:neuron_expressed
      WBPaper00049495:starvation-refeeding_regulated
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
      WBPaper00050468:hlh-30-dependent_Cry5B_regulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_specific
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053289:DREAM-target
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056826:SGP_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057041:spc-1(cas971)_downregulated
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00057162:meg-3_meg-4_upregulated_sRNA
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059471:EGL-43_interacting
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:URA_parent
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061527:C24A3.4_16071-ech-8
      WBPaper00061530:nhr-49(e2144)_downregulated
      WBPaper00061653:alh-4(hj221)_upregulated
      WBPaper00061699:daf-18(ok480)_downregulated
      WBPaper00062606:rotenone_upregulated
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064632:daf-2(e1370)_upregulated_intestine
      WBPaper00064716:paraquat_downregulated
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00025032:cluster_2
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00029437:rde-4_upregulated
      WBPaper00030985:Photorhabdus_luminescens_upregulated
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00034739:N2moreDR1350
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00036286:Pattern_D
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00040184:hcf-1up_sir-2.1up_daf-2up
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HQ_3d_0.2mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_prime
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00042234:xpa-1_upregulated
      WBPaper00044091:Bpseudomallei_induced_8h
      WBPaper00044091:Bpseudomallei_induced_12h
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00053236:daf-16(mgDF50)_regulated_Starved
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:cluster_2
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(83_min)
      [cgc5767]:expression_class_SE
      [cgc5767]:expression_class_SE_pi(83_min)
      [cgc6390]:Cluster_A
    Interaction: WBInteraction000008868
      WBInteraction000336528
  Map_info: Map: III Position: 13.2516 Error: 0.003717
    Positive: Positive_clone: C18D11 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00024788
    WBPaper00025957
    WBPaper00027024
    WBPaper00027392
    WBPaper00028338
    WBPaper00038491
    WBPaper00052849
    WBPaper00055090
    WBPaper00062625
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene