WormBase Tree Display for Gene: WBGene00009818
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| WBGene00009818 | SMap | S_parent | Sequence | F47B10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | acbp-3 | Person_evidence | WBPerson344 | |||||
| Sequence_name | F47B10.7 | ||||||||
| Molecular_name | F47B10.7 | ||||||||
| F47B10.7.1 | |||||||||
| CE32423 | |||||||||
| Other_name | CELE_F47B10.7 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | acbp-3 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:50 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 01 Apr 2005 11:05:24 | WBPerson2970 | Name_change | CGC_name | acbp-3 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | acbp | ||||||||
| Allele (42) | |||||||||
| Strain | WBStrain00032450 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00068338 | ||||||||
| 00068339 | |||||||||
| 00068340 | |||||||||
| 00068341 | |||||||||
| 00068342 | |||||||||
| 00117411 | |||||||||
| Ortholog (47) | |||||||||
| Paralog | WBGene00001153 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00007680 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00016655 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00018949 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00044603 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WBGene00012457 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| Structured_description | Concise_description | acbp-3 encodes a highly conserved protein containing a functional acyl-CoA-binding binding domain required for protein stability and ligand binding; mutant contains approximately 30% fewer lipid droplets and 20% less triglycerides; loss of ACBP-3 results in 35-40% reduction in lipid chain unsaturation; ACBP-3::GFP is predominantly expressed in hypodermis, body wall muscles and pharynx. | Paper_evidence | WBPaper00038378 | |||||
| Curator_confirmed | WBPerson12884 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 13 May 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable fatty-acyl-CoA binding activity. Involved in lipid storage. Predicted to be located in cytoplasm. Expressed in body wall musculature and pharynx. Human ortholog(s) of this gene implicated in retinal dystrophy with leukodystrophy. Is an ortholog of human ACBD4 (acyl-CoA binding domain containing 4) and ACBD5 (acyl-CoA binding domain containing 5). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0080946 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:23338) | ||||
| Molecular_info | Corresponding_CDS | F47B10.7 | |||||||
| Corresponding_CDS_history | F47B10.7:wp90 | ||||||||
| Corresponding_transcript | F47B10.7.1 | ||||||||
| Other_sequence (40) | |||||||||
| Associated_feature | WBsf648503 | ||||||||
| WBsf663282 | |||||||||
| WBsf663283 | |||||||||
| WBsf663284 | |||||||||
| WBsf718697 | |||||||||
| WBsf1006846 | |||||||||
| WBsf236316 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00015151 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00047600 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00032406 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr13618 | ||||||||
| Expr13621 | |||||||||
| Expr1026772 | |||||||||
| Expr1034289 | |||||||||
| Expr1151436 | |||||||||
| Expr2009115 | |||||||||
| Expr2027352 | |||||||||
| Drives_construct | WBCnstr00031895 | ||||||||
| WBCnstr00039884 | |||||||||
| Construct_product | WBCnstr00031895 | ||||||||
| WBCnstr00039884 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (218) | |||||||||
| Interaction (55) | |||||||||
| Map_info | Map | X | Position | 2.68331 | Error | 0.005475 | |||
| Positive | Positive_clone | F47B10 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00039062 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00065315 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
