WormBase Tree Display for Gene: WBGene00009818

WBGene00009818 SMap: S_parent: Sequence: F47B10
  Identity: Version: 2
    Name: CGC_name: acbp-3 Person_evidence: WBPerson344
      Sequence_name: F47B10.7
      Molecular_name: F47B10.7
        F47B10.7.1
        CE32423
      Other_name: CELE_F47B10.7 Accession_evidence: NDB BX284606
      Public_name: acbp-3
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:50 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 01 Apr 2005 11:05:24 WBPerson2970 Name_change: CGC_name: acbp-3
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: acbp
    Allele (42)
    Strain: WBStrain00032450
    RNASeq_FPKM (74)
    GO_annotation: 00068338
      00068339
      00068340
      00068341
      00068342
      00117411
    Ortholog (47)
    Paralog: WBGene00001153 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00007680 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00016655 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00018949 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00044603 Caenorhabditis elegans From_analysis: Panther
      WBGene00012457 Caenorhabditis elegans From_analysis: Panther
    Structured_description: Concise_description: acbp-3 encodes a highly conserved protein containing a functional acyl-CoA-binding binding domain required for protein stability and ligand binding; mutant contains approximately 30% fewer lipid droplets and 20% less triglycerides; loss of ACBP-3 results in 35-40% reduction in lipid chain unsaturation; ACBP-3::GFP is predominantly expressed in hypodermis, body wall muscles and pharynx. Paper_evidence: WBPaper00038378
          Curator_confirmed: WBPerson12884
            WBPerson1843
          Date_last_updated: 13 May 2011 00:00:00
      Automated_description: Predicted to enable fatty-acyl-CoA binding activity. Involved in lipid storage. Predicted to be located in cytoplasm. Expressed in body wall musculature and pharynx. Human ortholog(s) of this gene implicated in retinal dystrophy with leukodystrophy. Is an ortholog of human ACBD4 (acyl-CoA binding domain containing 4) and ACBD5 (acyl-CoA binding domain containing 5). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080946 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:23338)
  Molecular_info: Corresponding_CDS: F47B10.7
    Corresponding_CDS_history: F47B10.7:wp90
    Corresponding_transcript: F47B10.7.1
    Other_sequence (40)
    Associated_feature: WBsf648503
      WBsf663282
      WBsf663283
      WBsf663284
      WBsf718697
      WBsf1006846
      WBsf236316
  Experimental_info: RNAi_result: WBRNAi00015151 Inferred_automatically: RNAi_primary
      WBRNAi00047600 Inferred_automatically: RNAi_primary
      WBRNAi00032406 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr13618
      Expr13621
      Expr1026772
      Expr1034289
      Expr1151436
      Expr2009115
      Expr2027352
    Drives_construct: WBCnstr00031895
      WBCnstr00039884
    Construct_product: WBCnstr00031895
      WBCnstr00039884
    Microarray_results (19)
    Expression_cluster (218)
    Interaction: WBInteraction000156685
      WBInteraction000183211
      WBInteraction000202695
      WBInteraction000207604
      WBInteraction000245807
      WBInteraction000252892
      WBInteraction000255592
      WBInteraction000256286
      WBInteraction000259923
      WBInteraction000277827
      WBInteraction000278012
      WBInteraction000279660
      WBInteraction000287908
      WBInteraction000290873
      WBInteraction000300595
      WBInteraction000306261
      WBInteraction000307408
      WBInteraction000312763
      WBInteraction000321069
      WBInteraction000323101
      WBInteraction000323168
      WBInteraction000326114
      WBInteraction000326242
      WBInteraction000326254
      WBInteraction000329719
      WBInteraction000330012
      WBInteraction000344721
      WBInteraction000349386
      WBInteraction000359388
      WBInteraction000364948
      WBInteraction000372459
      WBInteraction000382575
      WBInteraction000382915
      WBInteraction000383380
      WBInteraction000387263
      WBInteraction000390046
      WBInteraction000391615
      WBInteraction000404083
      WBInteraction000406039
      WBInteraction000417653
      WBInteraction000418864
      WBInteraction000429231
      WBInteraction000433938
      WBInteraction000435046
      WBInteraction000441753
      WBInteraction000443047
      WBInteraction000460451
      WBInteraction000460542
      WBInteraction000550227
      WBInteraction000567856
      WBInteraction000576200
      WBInteraction000577894
      WBInteraction000578661
      WBInteraction000583806
      WBInteraction000584228
  Map_info: Map: X Position: 2.68331 Error: 0.005475
    Positive: Positive_clone: F47B10 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00039062
    WBPaper00055090
    WBPaper00065315
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene