WormBase Tree Display for Gene: WBGene00000175

WBGene00000175 Evidence: Person_evidence: WBPerson548
  SMap: S_parent: Sequence: M02F4
  Identity: Version: 1
    Name: CGC_name: aqp-7 Person_evidence: WBPerson300
      Sequence_name: M02F4.8
      Molecular_name: M02F4.8a
        M02F4.8a.1
        CE34058
        M02F4.8b
        CE04769
        M02F4.8a.2
        M02F4.8b.1
      Other_name: CELE_M02F4.8 Accession_evidence: NDB BX284606
      Public_name: aqp-7
    DB_info: Database: AceView gene XD645
        WormQTL gene WBGene00000175
        WormFlux gene WBGene00000175
        NDB locus_tag CELE_M02F4.8
        Panther gene CAEEL|WormBase=WBGene00000175|UniProtKB=Q21473
          family PTHR43829
        NCBI gene 180589
        RefSeq protein NM_001392739.1
            NM_001383537.2
        TrEMBL UniProtAcc A0A6V7QYI0
            Q21473
        UniProt_GCRP UniProtAcc A0A6V7QYI0
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: aqp
    Allele (24)
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog (29)
    Paralog: WBGene00000169 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000170 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000171 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000176 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00013272 Caenorhabditis elegans From_analysis: Panther
      WBGene00000172 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000173 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00000174 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: aqp-7 encodes an aquaglyceroporin whose expression in Xenopus oocytes increases either water or glycerol permeability five- to seven-fold; AQP-7 has no function in mass RNAi assays, perhaps reflecting genetic redundancy with its several paralogs; AQP-7 is expressed in muscle punctae (perhaps focal adhesions). Paper_evidence: WBPaper00029039
            WBPaper00030907
          Curator_confirmed: WBPerson567
          Date_last_updated: 12 Aug 2007 00:00:00
      Automated_description: Enables water channel activity. Involved in glycerol transmembrane transport and water transport. Predicted to be located in basolateral plasma membrane. Expressed in muscle cell. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS (2)
    Corresponding_CDS_history: M02F4.8:wp100
    Corresponding_transcript: M02F4.8a.1
      M02F4.8a.2
      M02F4.8b.1
    Other_sequence (53)
    Associated_feature (14)
  Experimental_info: RNAi_result (3)
    Expr_pattern: Expr4777
      Expr1023669
      Expr1030099
      Expr1154520
      Expr2009384
      Expr2027620
    Drives_construct: WBCnstr00012237
    Microarray_results (17)
    Expression_cluster: WBPaper00029047:atx-3_upregulated
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032425:down_in_alg-1
      WBPaper00032425:down_in_lin-35
      WBPaper00032528:L3_enriched
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00037946:LIN-39_interacting
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_adult_enriched
      WBPaper00037950:CEP-sheath-cells_adult_SelectivelyEnriched
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:hypodermis_larva_enriched
      WBPaper00037950:hypodermis_larva_SelectivelyEnriched
      WBPaper00038237:age-1_upregulated_intestine_rescue
      WBPaper00038237:age-1_upregulated_neuron_rescue
      WBPaper00038237:age-1_upregulated_nontransgenic
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:oscillating_dev_expression
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045521:Spermatogenic
      WBPaper00045774:clk-1_upregulated
      WBPaper00045934:wrn-1(gk99)_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049217:TCER-1_downregulated
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049626:UNC-75_target
      WBPaper00049736:daf-2(e1370)_downregulated_15deg-then-25deg(12hr)
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050053:muscle_enriched_Day4
      WBPaper00050096:P.aeruginosa_downregulated
      WBPaper00050121:mir-60(n4947)_upregulated
      WBPaper00050332:skn-1(RNAi)_downregulated
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050686:glp-1(e2141)_upregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:ash-2(RNAi)_regulated_germline
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:cytoplasm_specific
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051352:Long-Term-Association-Memory_downregulated
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053318:Aging_downregulated_mRNA_N2
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053599:mitosis_vs_meiosis_downregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053782:daf-2(RNAi)_oocyte_upregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00055049:S.gordonii_downregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055482:Tunicamycin_downregulated
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056139:gut-microbiota_downregulated
      WBPaper00056218:daf-16(mu86)_upregulated_Day3
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056443:DietaryRestriction_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056586:kri-1(ok1251)_upregulated
      WBPaper00056619:CEPsh_enriched
      WBPaper00056826:hmc_biased
      WBPaper00056868:P.aeruginosa_downregulated_smallRNA
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058691:set-2(bn129)_upregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00058942:henn-1(pk2295)_upregulated
      WBPaper00058948:PA14_upregulated
      WBPaper00059253:stearic-acid_upregulated
      WBPaper00059253:sucrose_stearic-acid_upregulated
      WBPaper00059253:sucrose_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059440:LAG-1_activated_4hr-auxin
      WBPaper00059471:EGL-43_interacting
      WBPaper00059566:wdr-23(mac32)_upregulated
      WBPaper00059567:olrn-1(ums9)_regulated
      WBPaper00059728:20ug_cholesterol_upregulated
      WBPaper00059816:crh-1(n3315)_downrgulated
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059895:wounding_downregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060084:cco-1(RNAi)_upregulated_lin-40(yth27)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060703:nas-38(ok3407)_downregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_protein
      WBPaper00061040:FW1256_upregulated
      WBPaper00061045:Y56A3A.22(cck200)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:AIB
      WBPaper00061340:CEPsh
      WBPaper00061340:PVR
      WBPaper00061340:SMB
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061479:hda-1(ne4747)_upregulated
      WBPaper00061479:prg-1(tm872)_upregulated
      WBPaper00061527:gpd-3_977-aldo-1_21168
      WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_downregulated
      WBPaper00061651:CEPsh_enriched
      WBPaper00061651:DB01_enriched
      WBPaper00061651:DB_enriched
      WBPaper00061651:Gonadal_sheath_cell_enriched
      WBPaper00061651:PDB_enriched
      WBPaper00061651:PLN_enriched
      WBPaper00061651:SAB_enriched
      WBPaper00061651:SDQ_enriched
      WBPaper00061651:SIA_enriched
      WBPaper00061651:SIB_enriched
      WBPaper00061651:SMB_enriched
      WBPaper00061651:VB01_enriched
      WBPaper00061651:VB02_enriched
      WBPaper00061651:VB_enriched
      WBPaper00061818:ELKS-1_interacting
      WBPaper00062156:jmjd-5(zr1234)_downregulated_germline
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062354:H.zoospora_12h_regulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064315:mes-3(bn199)_upregulated_EGCs
      WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs
      WBPaper00064637:cox-5B(RNAi)_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064952:Day10_vs_Day1_downregulated_25C
      WBPaper00065032:PAO1_vs_Delt.Pf4-infection_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:AFD_depleted
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065392:Lb.rhamnosus_upregulated
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065623:46
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:22_0
      WBPaper00065841:28_0
      WBPaper00065841:37_0
      WBPaper00065841:46_0
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066085:hda-3(ok1991)_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4489_group_1
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026980:intestine_enriched
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00031003:24hr_muscle_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00031060:2-deoxy-D-glucose_upregulated
      WBPaper00035227:heat_shock_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00038427:lin-54_germline_changed
      WBPaper00040963:Q50_up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HQ_3d_0.2mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041906:I-4317_vs_OP50_10d
      WBPaper00041960:daf-16_fasting_upregulated
      WBPaper00041960:kgb-1_fasting_upregulated
      WBPaper00041960:N2_fasting_upregulated
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00044091:Bpseudomallei_repressed_8h
      WBPaper00044091:Bpseudomallei_repressed_12h
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045960:L1-L4-lethargus_downregulated
      WBPaper00045960:L4-lethargus_downregulated
      WBPaper00048624:hlh-25(ok1710)_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00048989:N2_allantoin_downregulated
      WBPaper00050538:Fasting_upregulated
      WBPaper00050538:Fasting_upregulated_cholesterol-dependent
      WBPaper00057098:SiO2-nanoparticles_downregulated
    Interaction (17)
  Map_info: Map: X Position: -12.6524 Error: 0.00239
    Positive: Positive_clone: M02F4 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5291
    Pseudo_map_position
  Reference: WBPaper00029039
    WBPaper00038491
    WBPaper00055090
    WBPaper00062388
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene