WormBase Tree Display for Gene: WBGene00000172
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| WBGene00000172 | Evidence | Person_evidence | WBPerson548 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | CHROMOSOME_V | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | aqp-4 | Person_evidence | WBPerson300 | |||||
| Sequence_name | F40F9.9 | ||||||||
| Molecular_name | F40F9.9 | ||||||||
| F40F9.9.1 | |||||||||
| CE31345 | |||||||||
| Other_name | CELE_F40F9.9 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | aqp-4 | ||||||||
| DB_info | Database | AceView | gene | 5K225 | |||||
| WormQTL | gene | WBGene00000172 | |||||||
| WormFlux | gene | WBGene00000172 | |||||||
| NDB | locus_tag | CELE_F40F9.9 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000172|UniProtKB=G5EEK0 | |||||||
| family | PTHR45665 | ||||||||
| NCBI | gene | 179366 | |||||||
| RefSeq | protein | NM_073111.8 | |||||||
| TrEMBL | UniProtAcc | G5EEK0 | |||||||
| UniProt_GCRP | UniProtAcc | G5EEK0 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | aqp | ||||||||
| Allele (37) | |||||||||
| Strain | WBStrain00032651 | ||||||||
| WBStrain00007586 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Ortholog (40) | |||||||||
| Paralog | WBGene00000174 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| WormBase-Compara | |||||||||
| WBGene00000173 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00000169 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00000170 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00000171 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00000175 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00000176 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | aqp-4 encodes an aquaporin whose expression in Xenopus oocytes increases water permeability 5- to 10-fold; loss of AQP-4 activity via mutation or RNAi results in no obvious defects; however, AQP-4, in conjunction with AQP-2, AQP-3, and AQP-8, is weakly required for recovery from hypotonic stress; AQP-4 is expressed in the apical membrane of intestine; AQP-4 is paralogous to AQP-5 and AQP-6, and orthologous to human AQP8 (OMIM:603750). | Paper_evidence | WBPaper00004488 | |||||
| WBPaper00029039 | |||||||||
| WBPaper00030907 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 12 Aug 2007 00:00:00 | ||||||||
| Automated_description | Enables water channel activity. Involved in water transport. Located in apical plasma membrane. Expressed in intestine. Is an ortholog of human AQP8 (aquaporin 8). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F40F9.9 | |||||||
| Corresponding_CDS_history | F40F9.9:wp82 | ||||||||
| Corresponding_transcript | F40F9.9.1 | ||||||||
| Other_sequence (17) | |||||||||
| Associated_feature | WBsf647105 | ||||||||
| WBsf232292 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00014675 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00046891 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00101341 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00032043 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00101339 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr4774 | ||||||||
| Expr1019243 | |||||||||
| Expr1030097 | |||||||||
| Expr1150757 | |||||||||
| Expr2009381 | |||||||||
| Expr2027617 | |||||||||
| Drives_construct | WBCnstr00012234 | ||||||||
| WBCnstr00017547 | |||||||||
| WBCnstr00037688 | |||||||||
| Construct_product | WBCnstr00012234 | ||||||||
| WBCnstr00017547 | |||||||||
| WBCnstr00037688 | |||||||||
| Microarray_results (16) | |||||||||
| Expression_cluster (165) | |||||||||
| Interaction (31) | |||||||||
| Map_info | Map | V | Position | 2.13466 | Error | 0.004141 | |||
| Positive | Positive_clone | F40F9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00004488 | ||||||||
| WBPaper00010068 | |||||||||
| WBPaper00019560 | |||||||||
| WBPaper00027012 | |||||||||
| WBPaper00029039 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
